Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 79 results

4J2T
DownloadVisualize
BU of 4j2t by Molmil
Inhibitor-bound Ca2+ ATPase
Descriptor: (3S,3aR,4S,6S,6aR,7S,8S,9bS)-6-(acetyloxy)-3a,4-bis(butanoyloxy)-3-hydroxy-3,6,9-trimethyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}-2-oxo-2,3,3a,4,5,6,6a,7,8,9b-decahydroazuleno[4,5-b]furan-7-yl octanoate, PHOSPHATIDYLETHANOLAMINE, POTASSIUM ION, ...
Authors:Paulsen, E.S, Villadsen, J, Tenori, E, Liu, H, Lie, M.A, Bonde, D.F, Bublitz, M, Olesen, C, Autzen, H.E, Dach, I, Sehgal, P, Moller, J.V, Schiott, B, Nissen, P, Christensen, S.B.
Deposit date:2013-02-05
Release date:2013-06-19
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Water-mediated interactions influence the binding of thapsigargin to sarco/endoplasmic reticulum calcium adenosinetriphosphatase.
J.Med.Chem., 56, 2013
5A6I
DownloadVisualize
BU of 5a6i by Molmil
V122I Transthyretin structure in complex with Tolcalpone
Descriptor: TRANSTHYRETIN, Tolcapone
Authors:Reverter, D, Gallego, P, Santana, R, Ventura, S.
Deposit date:2015-06-26
Release date:2016-02-24
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Repositioning Tolcapone as a Potent Inhibitor of Transthyretin Amyloidogenesis and its Associated Cellular Toxicity
Nat.Commun., 7, 2016
2VQW
DownloadVisualize
BU of 2vqw by Molmil
Structure of inhibitor-free HDAC4 catalytic domain (with gain-of- function mutation His332Tyr)
Descriptor: HISTONE DEACETYLASE 4, POTASSIUM ION, ZINC ION
Authors:Bottomley, M.J, Lo Surdo, P, Di Giovine, P, Cirillo, A, Scarpelli, R, Ferrigno, F, Jones, P, Neddermann, P, De Francesco, R, Steinkuhler, C, Gallinari, P, Carfi, A.
Deposit date:2008-03-19
Release date:2008-08-05
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural and Functional Analysis of the Human Hdac4 Catalytic Domain Reveals a Regulatory Structural Zinc-Binding Domain.
J.Biol.Chem., 283, 2008
2VQM
DownloadVisualize
BU of 2vqm by Molmil
Structure of HDAC4 catalytic domain bound to a hydroxamic acid inhbitor
Descriptor: HISTONE DEACETYLASE 4, N-hydroxy-5-[(3-phenyl-5,6-dihydroimidazo[1,2-a]pyrazin-7(8H)-yl)carbonyl]thiophene-2-carboxamide, POTASSIUM ION, ...
Authors:Bottomley, M.J, Lo Surdo, P, Di Giovine, P, Cirillo, A, Scarpelli, R, Ferrigno, F, Jones, P, Neddermann, P, De Francesco, R, Steinkuhler, C, Gallinari, P, Carfi, A.
Deposit date:2008-03-17
Release date:2008-07-08
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and Functional Analysis of the Human Hdac4 Catalytic Domain Reveals a Regulatory Zinc-Binding Domain.
J.Biol.Chem., 283, 2008
5BTQ
DownloadVisualize
BU of 5btq by Molmil
Crystal structure of human heme oxygenase 1 H25R with biliverdin bound
Descriptor: BILIVERDINE IX ALPHA, Heme oxygenase 1, SULFATE ION
Authors:Caaveiro, J.M.M, Morante, K, Sigala, P, Tsumoto, K.
Deposit date:2015-06-03
Release date:2016-06-08
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:In-Cell Enzymology To Probe His-Heme Ligation in Heme Oxygenase Catalysis
Biochemistry, 55, 2016
2V5X
DownloadVisualize
BU of 2v5x by Molmil
Crystal structure of HDAC8-inhibitor complex
Descriptor: (2R)-N~8~-HYDROXY-2-{[(5-METHOXY-2-METHYL-1H-INDOL-3-YL)ACETYL]AMINO}-N~1~-[2-(2-PHENYL-1H-INDOL-3-YL)ETHYL]OCTANEDIAMIDE, HISTONE DEACETYLASE 8, POTASSIUM ION, ...
Authors:Di Marco, S, Vannini, A, Volpari, C, Gallinari, P, Jones, P, Mattu, M, Carfi, A, Defrancesco, R, Steinkuhler, C.
Deposit date:2007-07-10
Release date:2007-09-04
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Substrate Binding to Histone Deacetylases as Revealed by Crystal Structure of Hdac8-Substrate Complex
Embo Rep., 8, 2007
2VQO
DownloadVisualize
BU of 2vqo by Molmil
Structure of HDAC4 catalytic domain with a gain-of-function muation bound to a trifluoromethylketone inhbitor
Descriptor: 2,2,2-TRIFLUORO-1-{5-[(3-PHENYL-5,6-DIHYDROIMIDAZO[1,2-A]PYRAZIN-7(8H)-YL)CARBONYL]THIOPHEN-2-YL}ETHANE-1,1-DIOL, HISTONE DEACETYLASE 4, POTASSIUM ION, ...
Authors:Bottomley, M.J, Lo Surdo, P, Di Giovine, P, Cirillo, A, Scarpelli, R, Ferrigno, F, Jones, P, Neddermann, P, De Francesco, R, Steinkuhler, C, Gallinari, P, Carfi, A.
Deposit date:2008-03-18
Release date:2008-07-08
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural and Functional Analysis of the Human Hdac4 Catalytic Domain Reveals a Regulatory Zinc-Binding Domain.
J.Biol.Chem., 283, 2008
2VQQ
DownloadVisualize
BU of 2vqq by Molmil
Structure of HDAC4 catalytic domain (a double cysteine-to-alanine mutant) bound to a trifluoromethylketone inhbitor
Descriptor: 2,2,2-TRIFLUORO-1-{5-[(3-PHENYL-5,6-DIHYDROIMIDAZO[1,2-A]PYRAZIN-7(8H)-YL)CARBONYL]THIOPHEN-2-YL}ETHANE-1,1-DIOL, HISTONE DEACETYLASE 4, POTASSIUM ION, ...
Authors:Bottomley, M.J, Lo Surdo, P, Di Giovine, P, Cirillo, A, Scarpelli, R, Ferrigno, F, Jones, P, Neddermann, P, De Francesco, R, Steinkuhler, C, Gallinari, P, Carfi, A.
Deposit date:2008-03-18
Release date:2008-07-08
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and Functional Analysis of the Human Hdac4 Catalytic Domain Reveals a Regulatory Zinc-Binding Domain.
J.Biol.Chem., 283, 2008
2VQV
DownloadVisualize
BU of 2vqv by Molmil
Structure of HDAC4 catalytic domain with a gain-of-function mutation bound to a hydroxamic acid inhibitor
Descriptor: HISTONE DEACETYLASE 4, N-hydroxy-5-[(3-phenyl-5,6-dihydroimidazo[1,2-a]pyrazin-7(8H)-yl)carbonyl]thiophene-2-carboxamide, POTASSIUM ION, ...
Authors:Bottomley, M.J, Lo Surdo, P, Di Giovine, P, Cirillo, A, Scarpelli, R, Ferrigno, F, Jones, P, Neddermann, P, De Francesco, R, Steinkuhler, C, Gallinari, P, Carfi, A.
Deposit date:2008-03-19
Release date:2008-07-22
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural and Functional Analysis of the Human Hdac4 Catalytic Domain Reveals a Regulatory Structural Zinc-Binding Domain.
J.Biol.Chem., 283, 2008
2VQJ
DownloadVisualize
BU of 2vqj by Molmil
Structure of HDAC4 catalytic domain bound to a trifluoromethylketone inhbitor
Descriptor: 1,4-DIETHYLENE DIOXIDE, 2,2,2-TRIFLUORO-1-{5-[(3-PHENYL-5,6-DIHYDROIMIDAZO[1,2-A]PYRAZIN-7(8H)-YL)CARBONYL]THIOPHEN-2-YL}ETHANE-1,1-DIOL, HISTONE DEACETYLASE 4, ...
Authors:Bottomley, M.J, Lo Surdo, P, Di Giovine, P, Cirillo, A, Scarpelli, R, Ferrigno, F, Jones, P, Neddermann, P, De Francesco, R, Steinkuhler, C, Gallinari, P, Carfi, A.
Deposit date:2008-03-17
Release date:2008-07-08
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and Functional Analysis of the Human Hdac4 Catalytic Domain Reveals a Regulatory Zinc-Binding Domain.
J.Biol.Chem., 283, 2008
3OKJ
DownloadVisualize
BU of 3okj by Molmil
Alpha-keto-aldehyde binding mechanism reveals a novel lead structure motif for proteasome inhibition
Descriptor: N-[(benzyloxy)carbonyl]-L-leucyl-N-[(2S,3S)-3-hydroxy-1-(4-hydroxyphenyl)-4-oxobutan-2-yl]-L-leucinamide, Proteasome component C1, Proteasome component C11, ...
Authors:Groll, M, Poynor, M, Gallastegui, P, Stein, M, Schmidt, B, Kloetzel, P.M, Huber, R.
Deposit date:2010-08-25
Release date:2011-06-08
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Elucidation of the alpha-keto-aldehyde binding mechanism: a lead structure motif for proteasome inhibition
Angew.Chem.Int.Ed.Engl., 50, 2011
3IPT
DownloadVisualize
BU of 3ipt by Molmil
Crystal Structure of Ketosteroid Isomerase Y16S/D40N from Pseudomonas putida with Bound Equilenin
Descriptor: EQUILENIN, Steroid Delta-isomerase
Authors:Fenn, T.D, Sigala, P.A, Herschlag, D.
Deposit date:2009-08-18
Release date:2010-01-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.632 Å)
Cite:Dissecting the paradoxical effects of hydrogen bond mutations in the ketosteroid isomerase oxyanion hole.
Proc.Natl.Acad.Sci.USA, 107, 2010
5FO2
DownloadVisualize
BU of 5fo2 by Molmil
Structure of human transthyretin mutant A108I
Descriptor: TRANSTHYRETIN
Authors:Varejao, N, Santanna, R, Saraiva, M.J, Gallego, P, Ventura, S, Reverter, D.
Deposit date:2015-11-17
Release date:2016-11-30
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.449 Å)
Cite:Cavity filling mutations at the thyroxine-binding site dramatically increase transthyretin stability and prevent its aggregation.
Sci Rep, 7, 2017
6ZM9
DownloadVisualize
BU of 6zm9 by Molmil
PHAGE SAM LYASE IN COMPLEX WITH S-METHYL-5'-THIOADENOSINE
Descriptor: 5'-DEOXY-5'-METHYLTHIOADENOSINE, Chains: A, PHOSPHATE ION, ...
Authors:Guo, X, Kanchugal P, S, Selmer, M.
Deposit date:2020-07-02
Release date:2021-02-24
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structure and mechanism of a phage-encoded SAM lyase revises catalytic function of enzyme family.
Elife, 10, 2021
6ZMG
DownloadVisualize
BU of 6zmg by Molmil
PHAGE SAM LYASE IN COMPLEX WITH S-ADENOSYL-L-HOMOCYSTEINE
Descriptor: Chains: A, PHOSPHATE ION, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Guo, X, Kanchugal P, S, Selmer, M.
Deposit date:2020-07-02
Release date:2021-02-24
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Structure and mechanism of a phage-encoded SAM lyase revises catalytic function of enzyme family.
Elife, 10, 2021
6ZNB
DownloadVisualize
BU of 6znb by Molmil
PHAGE SAM LYASE IN APO STATE
Descriptor: PHOSPHATE ION, Phage SAM lyase Svi3-3
Authors:Eckhard, U, Kanchugal P, S, Selmer, M.
Deposit date:2020-07-06
Release date:2021-02-24
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure and mechanism of a phage-encoded SAM lyase revises catalytic function of enzyme family.
Elife, 10, 2021
1XD3
DownloadVisualize
BU of 1xd3 by Molmil
Crystal structure of UCHL3-UbVME complex
Descriptor: MAGNESIUM ION, METHYL 4-AMINOBUTANOATE, UBC protein, ...
Authors:Misaghi, S, Galardy, P.J, Meester, W.J.N, Ovaa, H, Ploegh, H.L, Gaudet, R.
Deposit date:2004-09-03
Release date:2004-11-23
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structure of the Ubiquitin Hydrolase UCH-L3 Complexed with a Suicide Substrate
J.Biol.Chem., 280, 2005
2BEQ
DownloadVisualize
BU of 2beq by Molmil
Structure of a Proteolytically Resistant Core from the Severe Acute Respiratory Syndrome Coronavirus S2 Fusion Protein
Descriptor: Spike glycoprotein
Authors:Supekar, V.M, Bruckmann, C, Ingallinella, P, Bianchi, E, Pessi, A, Carfi, A.
Deposit date:2004-11-29
Release date:2004-12-22
Last modified:2020-04-15
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of a Proteolytically Resistant Core from the Severe Acute Respiratory Syndrome Coronavirus S2 Fusion Protein
Proc.Natl.Acad.Sci.USA, 101, 2004
2BEZ
DownloadVisualize
BU of 2bez by Molmil
Structure of a proteolitically resistant core from the severe acute respiratory syndrome coronavirus S2 fusion protein
Descriptor: GLYCEROL, Spike glycoprotein
Authors:Supekar, V.M, Bruckmann, C, Ingallinella, P, Bianchi, E, Pessi, A, Carfi, A.
Deposit date:2004-12-02
Release date:2004-12-22
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of a Proteolytically Resistant Core from the Severe Acute Respiratory Syndrome Coronavirus S2 Fusion Protein
Proc.Natl.Acad.Sci.USA, 101, 2004
2INX
DownloadVisualize
BU of 2inx by Molmil
Crystal Structure of Ketosteroid Isomerase D40N from Pseudomonas putida (pKSI) with bound 2,6-difluorophenol
Descriptor: 2,6-DIFLUOROPHENOL, Steroid delta-isomerase
Authors:Martinez Caaveiro, J.M, Pybus, B, Ringe, D, Petsko, G.A, Sigala, P, Kraut, D, Herschlag, D.
Deposit date:2006-10-09
Release date:2007-10-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Testing geometrical discrimination within an enzyme active site: constrained hydrogen bonding in the ketosteroid isomerase oxyanion hole.
J.Am.Chem.Soc., 130, 2008
1I4U
DownloadVisualize
BU of 1i4u by Molmil
THE C1 SUBUNIT OF ALPHA-CRUSTACYANIN
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CRUSTACYANIN, SULFATE ION
Authors:Gordon, E.J, Leonard, G.A, McSweeney, S, Zagalsky, P.F.
Deposit date:2001-02-23
Release date:2001-09-19
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:The C1 subunit of alpha-crustacyanin: the de novo phasing of the crystal structure of a 40 kDa homodimeric protein using the anomalous scattering from S atoms combined with direct methods.
Acta Crystallogr.,Sect.D, 57, 2001
4E4J
DownloadVisualize
BU of 4e4j by Molmil
Crystal structure of arginine deiminase from Mycoplasma penetrans
Descriptor: Arginine deiminase, CHLORIDE ION
Authors:Benach, J, Gallego, P, Planell, R, Querol, E, Perez Pons, J.A, Reverter, D.
Deposit date:2012-03-13
Release date:2012-10-31
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Characterization of the Enzymes Composing the Arginine Deiminase Pathway in Mycoplasma penetrans.
Plos One, 7, 2012
1GKA
DownloadVisualize
BU of 1gka by Molmil
The molecular basis of the coloration mechanism in lobster shell. beta-crustacyanin at 3.2 A resolution
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ASTAXANTHIN, ...
Authors:Cianci, M, Rizkallah, P.J, Olczak, A, Raftery, J, Chayen, N.E, Zagalsky, P.F, Helliwell, J.R.
Deposit date:2001-08-10
Release date:2002-08-08
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3.23 Å)
Cite:The Molecular Basis of the Coloration Mechanism in Lobster Shell: Beta -Crustacyanin at 3.2-A Resolution
Proc.Natl.Acad.Sci.USA, 99, 2002
1H91
DownloadVisualize
BU of 1h91 by Molmil
The crystal structure of lobster apocrustacyanin A1 using softer X-rays.
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CRUSTACYANIN A1 SUBUNIT
Authors:Cianci, M, Rizkallah, P.J, Olczak, A, Raftery, J, Chayen, N.E, Zagalsky, P.F, Helliwell, J.R.
Deposit date:2001-02-21
Release date:2001-09-06
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structure of Lobster Apocrustacyanin A1 Using Softer X-Rays
Acta Crystallogr.,Sect.D, 57, 2001
1OBQ
DownloadVisualize
BU of 1obq by Molmil
Apocrustacyanin C1 crystals grown in space and earth using vapour diffusion geometry
Descriptor: CRUSTACYANIN C1 SUBUNIT
Authors:Habash, J, Boggon, T.J, Raftery, J, Chayen, N.E, Zagalsky, P.F, Helliwell, J.R.
Deposit date:2003-01-31
Release date:2003-07-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Apocrustacyanin C(1) Crystals Grown in Space and on Earth Using Vapour-Diffusion Geometry: Protein Structure Refinements and Electron-Density Map Comparisons
Acta Crystallogr.,Sect.D, 59, 2003

226707

PDB entries from 2024-10-30

PDB statisticsPDBj update infoContact PDBjnumon