Crystal structure of UCHL3-UbVME complex

Summary for 1XD3

Related1CMX 1UBQ 1UCH
DescriptorUbiquitin Carboxyl-terminal esterase L3, UBC protein, MAGNESIUM ION, ... (5 entities in total)
Functional Keywordsenzyme-ligand complex, active site crossover loop, hydrolase
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm P15374
Total number of polymer chains4
Total molecular weight69944.05
Misaghi, S.,Galardy, P.J.,Meester, W.J.N.,Ovaa, H.,Ploegh, H.L.,Gaudet, R. (deposition date: 2004-09-03, release date: 2004-11-23, Last modification date: 2011-07-13)
Primary citation
Misaghi, S.,Galardy, P.J.,Meester, W.J.N.,Ovaa, H.,Ploegh, H.L.,Gaudet, R.
Structure of the Ubiquitin Hydrolase UCH-L3 Complexed with a Suicide Substrate
J.Biol.Chem., 280:1512-1520, 2005
PubMed: 15531586 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M410770200
MImport into Mendeley
Experimental method
NMR Information

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.202600.7%1.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report