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PDB: 94 results

4W4K
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Crystal structure of a PE25-PPE41 heterodimer from a type VII secretion system of M. tuberculosis
Descriptor: PE family protein PE25, PPE family protein PPE41
Authors:Ekiert, D.C, Cox, J.S.
Deposit date:2014-08-14
Release date:2014-10-01
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure of a PE-PPE-EspG complex from Mycobacterium tuberculosis reveals molecular specificity of ESX protein secretion.
Proc.Natl.Acad.Sci.USA, 111, 2014
3GBN
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BU of 3gbn by Molmil
Crystal Structure of Fab CR6261 in Complex with the 1918 H1N1 influenza virus hemagglutinin
Descriptor: 1,2-ETHANEDIOL, 2-ETHOXYETHANOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Ekiert, D.C, Elsliger, M.A, Wilson, I.A.
Deposit date:2009-02-20
Release date:2009-03-10
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Antibody recognition of a highly conserved influenza virus epitope.
Science, 324, 2009
3GBM
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BU of 3gbm by Molmil
Crystal Structure of Fab CR6261 in Complex with a H5N1 influenza virus hemagglutinin.
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Ekiert, D.C, Elsliger, M.A, Wilson, I.A.
Deposit date:2009-02-20
Release date:2009-03-10
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Antibody recognition of a highly conserved influenza virus epitope.
Science, 324, 2009
4W4I
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BU of 4w4i by Molmil
Crystal structure of EspG3 from the ESX-3 type VII secretion system of M. tuberculosis
Descriptor: ESX-3 secretion-associated protein EspG3, SULFATE ION
Authors:Ekiert, D.C, Cox, J.S.
Deposit date:2014-08-14
Release date:2014-10-01
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structure of a PE-PPE-EspG complex from Mycobacterium tuberculosis reveals molecular specificity of ESX protein secretion.
Proc.Natl.Acad.Sci.USA, 111, 2014
3SDY
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BU of 3sdy by Molmil
Crystal Structure of Broadly Neutralizing Antibody CR8020 Bound to the Influenza A H3 Hemagglutinin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody CR8020, Heavy Chain, ...
Authors:Ekiert, D.C, Wilson, I.A.
Deposit date:2011-06-09
Release date:2011-07-20
Last modified:2021-04-07
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:A highly conserved neutralizing epitope on group 2 influenza A viruses.
Science, 333, 2011
4W4J
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BU of 4w4j by Molmil
Crystal structure of EspG3 from the ESX-3 type VII secretion system of M. smegmatis
Descriptor: EspG3, SULFATE ION
Authors:Ekiert, D.C, Cox, J.S.
Deposit date:2014-08-14
Release date:2014-10-01
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.803 Å)
Cite:Structure of a PE-PPE-EspG complex from Mycobacterium tuberculosis reveals molecular specificity of ESX protein secretion.
Proc.Natl.Acad.Sci.USA, 111, 2014
4W4L
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BU of 4w4l by Molmil
Crystal structure of EspG5 in complex with PE25 and PPE41 from the ESX-5 type VII secretion system of M. tuberculosis
Descriptor: 1,2-ETHANEDIOL, EspG5, PE family protein PE25, ...
Authors:Ekiert, D.C, Cox, J.S.
Deposit date:2014-08-14
Release date:2014-10-01
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structure of a PE-PPE-EspG complex from Mycobacterium tuberculosis reveals molecular specificity of ESX protein secretion.
Proc.Natl.Acad.Sci.USA, 111, 2014
3LZF
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BU of 3lzf by Molmil
Crystal Structure of Fab 2D1 in Complex with the 1918 Influenza Virus Hemagglutinin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2D1 Fab, ...
Authors:Ekiert, D.C, Wilson, I.A.
Deposit date:2010-03-01
Release date:2010-04-07
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis of preexisting immunity to the 2009 H1N1 pandemic influenza virus.
Science, 328, 2010
4K3E
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BU of 4k3e by Molmil
Crystal structure of bovine antibody BLV5B8 with ultralong CDR H3
Descriptor: BOVINE ANTIBODY WITH ULTRALONG CDR H3, HEAVY CHAIN, LIGHT CHAIN, ...
Authors:Ekiert, D.C, Wang, F, Wilson, I.A.
Deposit date:2013-04-10
Release date:2013-06-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Reshaping antibody diversity.
Cell(Cambridge,Mass.), 153, 2013
3QHZ
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BU of 3qhz by Molmil
Crystal Structure of human anti-influenza Fab 2D1
Descriptor: Human monoclonal antibody del2D1, Fab Heavy Chain, Fab Light Chain
Authors:Ekiert, D.C, Wilson, I.A.
Deposit date:2011-01-26
Release date:2011-02-16
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:An insertion mutation that distorts antibody binding site architecture enhances function of a human antibody.
MBio, 2, 2011
4K3D
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BU of 4k3d by Molmil
Crystal structure of bovine antibody BLV1H12 with ultralong CDR H3
Descriptor: BOVINE ANTIBODY WITH ULTRALONG CDR H3, HEAVY CHAIN, LIGHT CHAIN, ...
Authors:Ekiert, D.C, Wang, F, Wilson, I.A.
Deposit date:2013-04-10
Release date:2013-06-19
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Reshaping antibody diversity.
Cell(Cambridge,Mass.), 153, 2013
3QHF
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BU of 3qhf by Molmil
Crystal Structure of Fab del2D1, a deletion variant of anti-influenza antibody 2D1
Descriptor: Human monoclonal antibody del2D1, Fab Heavy Chain, Fab Light Chain
Authors:Ekiert, D.C, Wilson, I.A.
Deposit date:2011-01-25
Release date:2011-02-16
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.655 Å)
Cite:An insertion mutation that distorts antibody binding site architecture enhances function of a human antibody.
MBio, 2, 2011
3R2X
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BU of 3r2x by Molmil
Crystal structure of the de novo designed binding protein HB36.3 in complex the the 1918 influenza virus hemagglutinin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, HB36.3, designed hemagglutinin binding protein, ...
Authors:Ekiert, D.C, Wilson, I.A.
Deposit date:2011-03-14
Release date:2011-05-11
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Computational design of proteins targeting the conserved stem region of influenza hemagglutinin.
Science, 332, 2011
4GXV
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BU of 4gxv by Molmil
Crystal structure of anti-influenza virus antibody 1F1
Descriptor: Antibody 1F1, heavy chain, light chain
Authors:Ekiert, D.C, Wilson, I.A.
Deposit date:2012-09-04
Release date:2012-12-19
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.449 Å)
Cite:Influenza Human Monoclonal Antibody 1F1 Interacts with Three Major Antigenic Sites and Residues Mediating Human Receptor Specificity in H1N1 Viruses.
Plos Pathog., 8, 2012
4FNL
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BU of 4fnl by Molmil
Crystal structure of broadly neutralizing antibody C05
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Antibody C05, Heavy Chain, ...
Authors:Ekiert, D.C, Wilson, I.A.
Deposit date:2012-06-19
Release date:2012-09-19
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.297 Å)
Cite:Cross-neutralization of influenza A viruses mediated by a single antibody loop.
Nature, 489, 2012
4FQY
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BU of 4fqy by Molmil
Crystal structure of broadly neutralizing antibody CR9114 bound to H3 influenza hemagglutinin
Descriptor: Antibody CR9114 heavy chain, Antibody CR9114 light chain, Hemagglutinin HA1, ...
Authors:Ekiert, D.C, Dreyfus, C, Wilson, I.A.
Deposit date:2012-06-25
Release date:2012-08-22
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (5.253 Å)
Cite:Highly conserved protective epitopes on influenza B viruses.
Science, 337, 2012
4FQV
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BU of 4fqv by Molmil
Crystal structure of broadly neutralizing antibody CR9114 bound to H7 influenza hemagglutinin
Descriptor: Antibody CR9114 heavy chain, Antibody CR9114 light chain, Hemagglutinin HA1, ...
Authors:Ekiert, D.C, Dreyfus, C, Wilson, I.A.
Deposit date:2012-06-25
Release date:2012-08-22
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (5.75 Å)
Cite:Highly conserved protective epitopes on influenza B viruses.
Science, 337, 2012
4FP8
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BU of 4fp8 by Molmil
Crystal structure of broadly neutralizing antibody C05 bound to H3 influenza hemagglutinin, HA1 subunit
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody C05, ...
Authors:Ekiert, D.C, Wilson, I.A.
Deposit date:2012-06-21
Release date:2012-09-19
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.947 Å)
Cite:Cross-neutralization of influenza A viruses mediated by a single antibody loop.
Nature, 489, 2012
4GXU
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BU of 4gxu by Molmil
Crystal structure of antibody 1F1 bound to the 1918 influenza hemagglutinin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 1F1, heavy chain, ...
Authors:Ekiert, D.C, Wilson, I.A.
Deposit date:2012-09-04
Release date:2012-12-19
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3.294 Å)
Cite:Influenza Human Monoclonal Antibody 1F1 Interacts with Three Major Antigenic Sites and Residues Mediating Human Receptor Specificity in H1N1 Viruses.
Plos Pathog., 8, 2012
4FNK
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BU of 4fnk by Molmil
Crystal structure of the A/Hong Kong/1/1968 (H3N2) influenza virus hemagglutinin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
Authors:Ekiert, D.C, Wilson, I.A.
Deposit date:2012-06-19
Release date:2012-09-19
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.901 Å)
Cite:Cross-neutralization of influenza A viruses mediated by a single antibody loop.
Nature, 489, 2012
4FQR
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BU of 4fqr by Molmil
Crystal structure of broadly neutralizing antibody C05 bound to H3 influenza hemagglutinin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Broadly neutralizing antibody C05, ...
Authors:Ekiert, D.C, Wilson, I.A.
Deposit date:2012-06-25
Release date:2012-09-19
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:Cross-neutralization of influenza A viruses mediated by a single antibody loop.
Nature, 489, 2012
4GXX
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BU of 4gxx by Molmil
Crystal structure of the "avianized" 1918 influenza virus hemagglutinin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, ...
Authors:Ekiert, D.C, Wilson, I.A.
Deposit date:2012-09-04
Release date:2012-12-19
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.799 Å)
Cite:Influenza Human Monoclonal Antibody 1F1 Interacts with Three Major Antigenic Sites and Residues Mediating Human Receptor Specificity in H1N1 Viruses.
Plos Pathog., 8, 2012
7SEE
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BU of 7see by Molmil
Structure of E. coli LetB delta (Ring6) mutant, Ring1 in the closed state (Model 1)
Descriptor: MCE family protein, Intermembrane transport protein YebT chimera, UNKNOWN ATOM OR ION
Authors:Vieni, C, Coudray, N, Bhabha, G, Ekiert, D.
Deposit date:2021-09-30
Release date:2022-02-09
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Role of Ring6 in the Function of the E. coli MCE Protein LetB.
J.Mol.Biol., 434, 2022
7SEF
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BU of 7sef by Molmil
Structure of E. coli LetB delta (Ring6) mutant, Ring 1 in the open state (Model 2, Rings 1-3 only)
Descriptor: MCE family protein, Intermembrane transport protein YebT chimera
Authors:Vieni, C, Coudray, N, Bhabha, G, Ekiert, D.
Deposit date:2021-09-30
Release date:2022-02-09
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.55 Å)
Cite:Role of Ring6 in the Function of the E. coli MCE Protein LetB.
J.Mol.Biol., 434, 2022
7MI8
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BU of 7mi8 by Molmil
Signal subtracted reconstruction of AAA5 and AAA6 domains of dynein in the presence of a pyrazolo-pyrimidinone-based compound, Model 5
Descriptor: Fusion protein of Dynein and Endolysin
Authors:Santarossa, C.C, Coudray, N, Urnavicius, L, Ekiert, D.C, Bhabha, G, Kapoor, T.M.
Deposit date:2021-04-16
Release date:2021-05-26
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Targeting allostery in the Dynein motor domain with small molecule inhibitors.
Cell Chem Biol, 28, 2021

 

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