4FQV

Crystal structure of broadly neutralizing antibody CR9114 bound to H7 influenza hemagglutinin

Summary for 4FQV

Entry DOI	10.2210/pdb4fqv/pdb
Related	4FNK 4FQH 4FQI 4FQJ 4FQK 4FQL 4FQM 4FQY
Descriptor	Hemagglutinin HA1, Hemagglutinin HA2, Antibody CR9114 heavy chain, ... (4 entities in total)
Functional Keywords	viral fusion protein, immunoglobulin, virus attachment and entry, immune recognition, viral protein-immune system complex, viral protein/immune system
Biological source	Influenza A virus More
Cellular location	Host apical cell membrane ; Single-pass type I membrane protein : Q6VMK1 Q6VMK1
Total number of polymer chains	12
Total formula weight	307968.69
Authors	Ekiert, D.C.,Dreyfus, C.,Wilson, I.A. (deposition date: 2012-06-25, release date: 2012-08-22, Last modification date: 2018-01-31)
Primary citation	Dreyfus, C.,Laursen, N.S.,Kwaks, T.,Zuijdgeest, D.,Khayat, R.,Ekiert, D.C.,Lee, J.H.,Metlagel, Z.,Bujny, M.V.,Jongeneelen, M.,van der Vlugt, R.,Lamrani, M.,Korse, H.J.,Geelen, E.,Sahin, O.,Sieuwerts, M.,Brakenhoff, J.P.,Vogels, R.,Li, O.T.,Poon, L.L.,Peiris, M.,Koudstaal, W.,Ward, A.B.,Wilson, I.A.,Goudsmit, J.,Friesen, R.H. Highly conserved protective epitopes on influenza B viruses. Science, 337:1343-1348, 2012 Cited by PubMed: 22878502 DOI: 10.1126/science.1222908 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (5.75 Å)

Structure validation