4FQV
Crystal structure of broadly neutralizing antibody CR9114 bound to H7 influenza hemagglutinin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E (A, C, E) | Hemagglutinin HA1 | polymer | 327 | 35894.4 | 3 | UniProt (Q6VMK1) Pfam (PF00509) | Influenza A virus | hemagglutinin receptor binding subunit HA1 |
| 2 | B, D, F (B, D, F) | Hemagglutinin HA2 | polymer | 176 | 20327.3 | 3 | UniProt (Q6VMK1) Pfam (PF00509) | Influenza A virus | hemagglutinin membrane fusion subunit HA2 |
| 3 | G, I, K (H, I, J) | Antibody CR9114 heavy chain | polymer | 224 | 23594.3 | 3 | Homo sapiens (human) | ||
| 4 | H, J, L (L, M, N) | Antibody CR9114 light chain | polymer | 216 | 22840.2 | 3 | Homo sapiens (human) |
Sequence modifications
A, C, E: 11 - 332 (UniProt: Q6VMK1)
| PDB | External Database | Details |
|---|---|---|
| Ala 7 | - | expression tag |
| Asp 8 | - | expression tag |
| Pro 9 | - | expression tag |
| Gly 10 | - | expression tag |
| Leu 254 | Pro 270 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 307968.7 | |
| All* | Total formula weight | 307968.7 |
