4FQY

Crystal structure of broadly neutralizing antibody CR9114 bound to H3 influenza hemagglutinin

Summary for 4FQY

• Entry DOI: 10.2210/pdb4fqy/pdb
• Related: 4FNK 4FQH 4FQI 4FQJ 4FQK 4FQL 4FQM 4FQV
• Descriptor: Hemagglutinin HA1, Hemagglutinin HA2, Antibody CR9114 heavy chain, ... (4 entities in total)
• Functional Keywords: viral fusion protein, immunoglobulin, virus attachment and entry, immune recognition, viral protein-immune system complex, viral protein/immune system
• Biological source: Influenza A virus; More
• Cellular location: Virion membrane ; Single-pass type I membrane protein : Q91MA7 Q91MA7
• Total number of polymer chains: 4
• Total formula weight: 101982.56

Authors

Ekiert, D.C.,Dreyfus, C.,Wilson, I.A. (deposition date: 2012-06-25, release date: 2012-08-22, Last modification date: 2018-01-31)

• Primary citation: Dreyfus, C.,Laursen, N.S.,Kwaks, T.,Zuijdgeest, D.,Khayat, R.,Ekiert, D.C.,Lee, J.H.,Metlagel, Z.,Bujny, M.V.,Jongeneelen, M.,van der Vlugt, R.,Lamrani, M.,Korse, H.J.,Geelen, E.,Sahin, O.,Sieuwerts, M.,Brakenhoff, J.P.,Vogels, R.,Li, O.T.,Poon, L.L.,Peiris, M.,Koudstaal, W.,Ward, A.B.,Wilson, I.A.,Goudsmit, J.,Friesen, R.H.; Highly conserved protective epitopes on influenza B viruses.; Science, 337:1343-1348, 2012; PubMed: 22878502; DOI: 10.1126/science.1222908

Experimental method

X-RAY DIFFRACTION (5.253 Å)