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4FQY

Crystal structure of broadly neutralizing antibody CR9114 bound to H3 influenza hemagglutinin

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Hemagglutinin HA1polymer32335506.91UniProt (Q91MA7)
Pfam (PF00509)
Influenza A virushemagglutinin receptor binding subunit HA1
2B
(B)
Hemagglutinin HA2polymer17420041.11UniProt (Q91MA7)
Pfam (PF00509)
Influenza A virushemagglutinin membrane fusion subunit HA2
3C
(H)
Antibody CR9114 heavy chainpolymer22423594.31Homo sapiens (human)
4D
(L)
Antibody CR9114 light chainpolymer21622840.21Homo sapiens (human)
Sequence modifications
A: 11 - 329 (UniProt: Q91MA7)
PDBExternal DatabaseDetails
Ala 7-expression tag
Asp 8-expression tag
Pro 9-expression tag
Gly 10-expression tag
B: 1 - 174 (UniProt: Q91MA7)
PDBExternal DatabaseDetails
Gly 123Arg 468SEE REMARK 999
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight101982.6
All*Total formula weight101982.6
*Water molecules are not included.

237735

PDB entries from 2025-06-18

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