4GXX

Crystal structure of the "avianized" 1918 influenza virus hemagglutinin

Summary for 4GXX

Entry DOI	10.2210/pdb4gxx/pdb
Related	4GXU 4GXV
Descriptor	Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
Functional Keywords	viral fusion protein, virus attachment and entry, viral protein
Biological source	Influenza A virus More
Cellular location	Virion membrane; Single-pass type I membrane protein (Potential): Q9WFX3 Q9WFX3
Total number of polymer chains	6
Total formula weight	172857.80
Authors	Ekiert, D.C.,Wilson, I.A. (deposition date: 2012-09-04, release date: 2012-12-19, Last modification date: 2023-09-13)
Primary citation	Tsibane, T.,Ekiert, D.C.,Krause, J.C.,Martinez, O.,Crowe, J.E.,Wilson, I.A.,Basler, C.F. Influenza Human Monoclonal Antibody 1F1 Interacts with Three Major Antigenic Sites and Residues Mediating Human Receptor Specificity in H1N1 Viruses. Plos Pathog., 8:e1003067-e1003067, 2012 Cited by PubMed: 23236279 DOI: 10.1371/journal.ppat.1003067 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.799 Å)

Structure validation