7MI8

Signal subtracted reconstruction of AAA5 and AAA6 domains of dynein in the presence of a pyrazolo-pyrimidinone-based compound, Model 5

Summary for 7MI8

Entry DOI	10.2210/pdb7mi8/pdb
EMDB information	23842
Descriptor	Fusion protein of Dynein and Endolysin (1 entity in total)
Functional Keywords	aaa atpase, atpase inhibitor, motor protein
Biological source	Saccharomyces cerevisiae (Baker's yeast) More
Total number of polymer chains	1
Total formula weight	304889.88
Authors	Santarossa, C.C.,Coudray, N.,Urnavicius, L.,Ekiert, D.C.,Bhabha, G.,Kapoor, T.M. (deposition date: 2021-04-16, release date: 2021-05-26, Last modification date: 2021-11-03)
Primary citation	Santarossa, C.C.,Mickolajczyk, K.J.,Steinman, J.B.,Urnavicius, L.,Chen, N.,Hirata, Y.,Fukase, Y.,Coudray, N.,Ekiert, D.C.,Bhabha, G.,Kapoor, T.M. Targeting allostery in the Dynein motor domain with small molecule inhibitors. Cell Chem Biol, 28:1460-1473.e15, 2021 Cited by PubMed: 34015309 DOI: 10.1016/j.chembiol.2021.04.024 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.7 Å)

Structure validation