4FP8

Crystal structure of broadly neutralizing antibody C05 bound to H3 influenza hemagglutinin, HA1 subunit

Summary for 4FP8

Entry DOI	10.2210/pdb4fp8/pdb
Related	4FNK 4FNL 4FQR
EMDB information	2138 2139 2140
Descriptor	Hemagglutinin HA1 chain, Antibody C05, heavy chain, Antibody C05, light chain, ... (6 entities in total)
Functional Keywords	viral fusion protein, immunoglobulin, virus attachment and entry, immune recognition, viral protein-immune system complex, viral protein/immune system
Biological source	Influenza A virus More
Total number of polymer chains	12
Total formula weight	319681.41
Authors	Ekiert, D.C.,Wilson, I.A. (deposition date: 2012-06-21, release date: 2012-09-19, Last modification date: 2023-09-13)
Primary citation	Ekiert, D.C.,Kashyap, A.K.,Steel, J.,Rubrum, A.,Bhabha, G.,Khayat, R.,Lee, J.H.,Dillon, M.A.,O'Neil, R.E.,Faynboym, A.M.,Horowitz, M.,Horowitz, L.,Ward, A.B.,Palese, P.,Webby, R.,Lerner, R.A.,Bhatt, R.R.,Wilson, I.A. Cross-neutralization of influenza A viruses mediated by a single antibody loop. Nature, 489:526-532, 2012 Cited by PubMed: 22982990 DOI: 10.1038/nature11414 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.947 Å)

Structure validation