3LZF

Crystal Structure of Fab 2D1 in Complex with the 1918 Influenza Virus Hemagglutinin

Summary for 3LZF

• Entry DOI: 10.2210/pdb3lzf/pdb
• Related: 3LZG
• Descriptor: Hemagglutinin, HA1 Subunit, Hemagglutinin, HA2 Subunit, 2D1 Fab, Heavy Chain, ... (7 entities in total)
• Functional Keywords: hemagglutinin, fab, neutralizing antibodies, antibody, pandemic flu, swine flu, envelope protein, fusion protein, glycoprotein, antigen, virion, viral protein-immune system complex, viral protein/immune system
• Biological source: Influenza A virus (Influenza A virus); More
• Cellular location: Virion membrane; Single-pass type I membrane protein (Potential): Q9WFX3 Q9WFX3
• Total number of polymer chains: 4
• Total formula weight: 106177.88

Authors

Ekiert, D.C.,Wilson, I.A. (deposition date: 2010-03-01, release date: 2010-04-07, Last modification date: 2020-07-29)

• Primary citation: Xu, R.,Ekiert, D.C.,Krause, J.C.,Hai, R.,Crowe, J.E.,Wilson, I.A.; Structural basis of preexisting immunity to the 2009 H1N1 pandemic influenza virus.; Science, 328:357-360, 2010; PubMed: 20339031; DOI: 10.1126/science.1186430

Experimental method

X-RAY DIFFRACTION (2.8 Å)