3LZF
Crystal Structure of Fab 2D1 in Complex with the 1918 Influenza Virus Hemagglutinin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Hemagglutinin, HA1 Subunit | polymer | 331 | 36452.8 | 1 | UniProt (Q9WFX3) Pfam (PF00509) | Influenza A virus (Influenza A virus) | Hemagglutinin HA1 chain, Hemagglutinin HA2 chain |
| 2 | B (B) | Hemagglutinin, HA2 Subunit | polymer | 179 | 20394.4 | 1 | UniProt (Q9WFX3) Pfam (PF00509) | Influenza A virus (Influenza A virus) | Hemagglutinin HA1 chain, Hemagglutinin HA2 chain |
| 3 | C (H) | 2D1 Fab, Heavy Chain | polymer | 230 | 24699.8 | 1 | Homo sapiens | ||
| 4 | D (L) | 2D1 Fab, Light Chain | polymer | 217 | 22812.1 | 1 | Homo sapiens | ||
| 5 | E, G (C, E) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 6 | F (D) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G81315DD) | |||
| 7 | H (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) |
Sequence modifications
A: 11 - 329 (UniProt: Q9WFX3)
B: 1 - 176 (UniProt: Q9WFX3)
| PDB | External Database | Details |
|---|---|---|
| Ala 7 | - | expression tag |
| Asp 8 | - | expression tag |
| Pro 9 | - | expression tag |
| Gly 10 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser 177 | - | expression tag |
| Gly 178 | - | expression tag |
| Arg 179 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 104359.2 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 1597.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 221.2 | |
| All* | Total formula weight | 106177.9 |
