4FNL

Crystal structure of broadly neutralizing antibody C05

Summary for 4FNL

Entry DOI	10.2210/pdb4fnl/pdb
Related	4FNK 4FP8 4FQR
EMDB information	2138 2139 2140
Descriptor	Antibody C05, Heavy Chain, Antibody C05, Light Chain, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (4 entities in total)
Functional Keywords	immunoglobulin, immune recognition, immune system
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	99462.70
Authors	Ekiert, D.C.,Wilson, I.A. (deposition date: 2012-06-19, release date: 2012-09-19, Last modification date: 2023-09-13)
Primary citation	Ekiert, D.C.,Kashyap, A.K.,Steel, J.,Rubrum, A.,Bhabha, G.,Khayat, R.,Lee, J.H.,Dillon, M.A.,O'Neil, R.E.,Faynboym, A.M.,Horowitz, M.,Horowitz, L.,Ward, A.B.,Palese, P.,Webby, R.,Lerner, R.A.,Bhatt, R.R.,Wilson, I.A. Cross-neutralization of influenza A viruses mediated by a single antibody loop. Nature, 489:526-532, 2012 Cited by PubMed: 22982990 DOI: 10.1038/nature11414 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.297 Å)

Structure validation