4WYB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4wyb by Molmil](/molmil-images/mine/4wyb) | Structure of the Bud6 flank domain in complex with actin | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Eck, M.J, Park, E, Zheng, W. | Deposit date: | 2014-11-17 | Release date: | 2015-08-19 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.493 Å) | Cite: | Structure of a Bud6/Actin Complex Reveals a Novel WH2-like Actin Monomer Recruitment Motif. Structure, 23, 2015
|
|
8DGS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8dgs by Molmil](/molmil-images/mine/8dgs) | Cryo-EM structure of a RAS/RAF complex (state 1) | Descriptor: | 14-3-3 protein zeta, 5-[(2-fluoro-4-iodophenyl)amino]-N-(2-hydroxyethoxy)imidazo[1,5-a]pyridine-6-carboxamide, Dual specificity mitogen-activated protein kinase kinase 1, ... | Authors: | Eck, M.J, Jeon, H, Park, E, Rawson, S. | Deposit date: | 2022-06-24 | Release date: | 2023-07-05 | Last modified: | 2023-08-09 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Cryo-EM structure of a RAS/RAF recruitment complex. Nat Commun, 14, 2023
|
|
8DGT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8dgt by Molmil](/molmil-images/mine/8dgt) | Cryo-EM structure of a RAS/RAF complex (state 2) | Descriptor: | 14-3-3 protein zeta, 5-[(2-fluoro-4-iodophenyl)amino]-N-(2-hydroxyethoxy)imidazo[1,5-a]pyridine-6-carboxamide, Dual specificity mitogen-activated protein kinase kinase 1, ... | Authors: | Eck, M.J, Jeon, H, Park, E, Rawson, S. | Deposit date: | 2022-06-24 | Release date: | 2023-07-05 | Last modified: | 2023-08-09 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Cryo-EM structure of a RAS/RAF recruitment complex. Nat Commun, 14, 2023
|
|
4ZJV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4zjv by Molmil](/molmil-images/mine/4zjv) | |
1TNF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1tnf by Molmil](/molmil-images/mine/1tnf) | |
5U1M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5u1m by Molmil](/molmil-images/mine/5u1m) | |
4K11
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4k11 by Molmil](/molmil-images/mine/4k11) | The structure of 1NA in complex with Src T338G | Descriptor: | 1-tert-butyl-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Proto-oncogene tyrosine-protein kinase Src | Authors: | Eck, M.J, Yun, C.H. | Deposit date: | 2013-04-04 | Release date: | 2014-04-09 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The structure of 1NA in complex with Src T338G To be Published
|
|
3O4X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3o4x by Molmil](/molmil-images/mine/3o4x) | |
1QZY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1qzy by Molmil](/molmil-images/mine/1qzy) | Human Methionine Aminopeptidase in complex with bengamide inhibitor LAF153 and cobalt | Descriptor: | (E)-(2R,3R,4S,5R)-3,4,5-TRIHYDROXY-2-METHOXY-8,8-DIMETHYL-NON-6-ENOIC ACID ((3S,6R)-6-HYDROXY-2-OXO-AZEPAN-3-YL)-AMIDE, COBALT (II) ION, Methionine aminopeptidase 2, ... | Authors: | Eck, M.J, Song, H.K, Morollo, A. | Deposit date: | 2003-09-18 | Release date: | 2003-11-25 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Proteomics-based target identification: bengamides as a new class of methionine aminopeptidase inhibitors. J.Biol.Chem., 278, 2003
|
|
1LCK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1lck by Molmil](/molmil-images/mine/1lck) | |
1LCJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1lcj by Molmil](/molmil-images/mine/1lcj) | |
7M8H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7m8h by Molmil](/molmil-images/mine/7m8h) | Structure of Memo1 C244S metal binding site mutant at 1.75A | Descriptor: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, ... | Authors: | Boniecki, M.T, Uhlemann, E.E, Dmitriev, O.Y. | Deposit date: | 2021-03-29 | Release date: | 2022-04-06 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | MEMO1 binds iron and modulates iron homeostasis in cancer cells. Elife, 13, 2024
|
|
5WKP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5wkp by Molmil](/molmil-images/mine/5wkp) | |
7RTK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7rtk by Molmil](/molmil-images/mine/7rtk) | Structure of the (NIAU)2 complex with N-terminal mutation of ISCU2 Y35D at 2.5 A resolution | Descriptor: | 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL, ... | Authors: | Boniecki, M.T, Cygler, M. | Deposit date: | 2021-08-13 | Release date: | 2021-08-25 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The essential function of ISCU2 and its conserved N-terminus in Fe/S cluster biogenesis To Be Published
|
|
4W4G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4w4g by Molmil](/molmil-images/mine/4w4g) | Postcleavage state of 70S bound to HigB toxin and AAA (lysine) codon | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Schureck, M.A, Maehigashi, T, Dunkle, J.A, Dunham, C.M. | Deposit date: | 2014-08-14 | Release date: | 2015-10-21 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Defining the mRNA recognition signature of a bacterial toxin protein. Proc.Natl.Acad.Sci.USA, 112, 2015
|
|
4U7A
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4u7a by Molmil](/molmil-images/mine/4u7a) | |
5WGB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5wgb by Molmil](/molmil-images/mine/5wgb) | |
5WLW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5wlw by Molmil](/molmil-images/mine/5wlw) | |
6UXE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6uxe by Molmil](/molmil-images/mine/6uxe) | Structure of the human mitochondrial desulfurase complex Nfs1-ISCU2(M140I)-ISD11 with E.coli ACP1 at 1.57 A resolution showing flexibility of N terminal end of ISCU2 | Descriptor: | 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL, ... | Authors: | Boniecki, M.T, Cygler, M. | Deposit date: | 2019-11-07 | Release date: | 2019-11-20 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.57 Å) | Cite: | The essential function of ISCU2 and its conserved N-terminus in Fe/S cluster biogenesis To Be Published
|
|
6WI2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6wi2 by Molmil](/molmil-images/mine/6wi2) | |
6W1D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6w1d by Molmil](/molmil-images/mine/6w1d) | Structure of human mitochondrial complex Nfs1-ISCU2 (WT)-ISD11 with E.coli ACP1 at 1.8 A resolution (NIAU)2 | Descriptor: | 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL, ... | Authors: | Boniecki, M.T, Cygler, M. | Deposit date: | 2020-03-04 | Release date: | 2020-03-18 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.795 Å) | Cite: | The essential function of ISCU2 and its conserved N-terminus in Fe/S cluster biogenesis To Be Published
|
|
6WIH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6wih by Molmil](/molmil-images/mine/6wih) | N-terminal mutation of ISCU2 (L35H36) traps Nfs1 Cys loop in the active site of ISCU2 without metal present. Structure of human mitochondrial complex Nfs1-ISCU2(L35H36)-ISD11 with E.coli ACP1 at 1.9 A resolution (NIAU)2. | Descriptor: | 1,2-ETHANEDIOL, 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL, Acyl carrier protein, ... | Authors: | Boniecki, M.T, Cygler, M. | Deposit date: | 2020-04-09 | Release date: | 2020-05-13 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The essential function of ISCU2 and its conserved N-terminus in Fe/S cluster biogenesis To Be Published
|
|
3KZP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3kzp by Molmil](/molmil-images/mine/3kzp) | Crystal structure of putative diguanylate cyclase/phosphodiesterase from Listaria monocytigenes | Descriptor: | CACODYLATE ION, CALCIUM ION, CHLORIDE ION, ... | Authors: | Klimecka, M.M, Chruszcz, M, Zimmerman, M.D, Kudritska, M, Savchenko, A, Edwards, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2009-12-08 | Release date: | 2009-12-22 | Last modified: | 2022-04-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of putative diguanylate cyclase/phosphodiesterase from Listaria monocytigenes To be Published
|
|
3KZL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3kzl by Molmil](/molmil-images/mine/3kzl) | Crystal structure of BA2930 mutant (H183G) in complex with AcCoA | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETYL COENZYME *A, Aminoglycoside N3-acetyltransferase, ... | Authors: | Klimecka, M.M, Chruszcz, M, Porebski, P.J, Cymborowski, M, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2009-12-08 | Release date: | 2009-12-22 | Last modified: | 2022-04-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural Analysis of a Putative Aminoglycoside N-Acetyltransferase from Bacillus anthracis. J.Mol.Biol., 410, 2011
|
|
7SH4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7sh4 by Molmil](/molmil-images/mine/7sh4) | CD1a-phosphatidylglycerol binary structure | Descriptor: | (21R,24R,27S)-24,27,28-trihydroxy-18,24-dioxo-19,23,25-trioxa-24lambda~5~-phosphaoctacosan-21-yl (9Z)-octadec-9-enoate, 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... | Authors: | Wegrecki, M, Rossjohn, J. | Deposit date: | 2021-10-07 | Release date: | 2022-10-05 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Staphylococcal phosphatidylglycerol antigens activate human T cells via CD1a. Nat.Immunol., 24, 2023
|
|