7M8H

Structure of Memo1 C244S metal binding site mutant at 1.75A

Summary for 7M8H

Entry DOI	10.2210/pdb7m8h/pdb
Related	7KQ8 7L5C
Descriptor	Protein MEMO1, GLUTATHIONE, 1,2-ETHANEDIOL, ... (7 entities in total)
Functional Keywords	metal binding protein, breast cancer, iron binding protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	4
Total formula weight	138098.65
Authors	Boniecki, M.T.,Uhlemann, E.E.,Dmitriev, O.Y. (deposition date: 2021-03-29, release date: 2022-04-06, Last modification date: 2024-05-22)
Primary citation	Dolgova, N.,Uhlemann, E.E.,Boniecki, M.T.,Vizeacoumar, F.S.,Ara, A.,Nouri, P.,Ralle, M.,Tonelli, M.,Abbas, S.A.,Patry, J.,Elhasasna, H.,Freywald, A.,Vizeacoumar, F.J.,Dmitriev, O.Y. MEMO1 binds iron and modulates iron homeostasis in cancer cells. Elife, 13:-, 2024 Cited by PubMed: 38640016 DOI: 10.7554/eLife.86354 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.75 Å)

Structure validation