Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005634 | cellular_component | nucleus |
| A | 0005829 | cellular_component | cytosol |
| A | 0032886 | biological_process | regulation of microtubule-based process |
| B | 0005634 | cellular_component | nucleus |
| B | 0005829 | cellular_component | cytosol |
| B | 0032886 | biological_process | regulation of microtubule-based process |
| C | 0005634 | cellular_component | nucleus |
| C | 0005829 | cellular_component | cytosol |
| C | 0032886 | biological_process | regulation of microtubule-based process |
| D | 0005634 | cellular_component | nucleus |
| D | 0005829 | cellular_component | cytosol |
| D | 0032886 | biological_process | regulation of microtubule-based process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | binding site for residue GSH A 301 |
| Chain | Residue |
| A | SER15 |
| A | TYR289 |
| A | MES304 |
| A | HOH408 |
| A | HOH430 |
| A | HOH460 |
| A | HOH489 |
| A | HOH556 |
| D | SER15 |
| D | TRP16 |
| D | GSH301 |
| A | TRP16 |
| A | HIS49 |
| A | ALA50 |
| A | GLY51 |
| A | TYR54 |
| A | ASP189 |
| A | HIS192 |
| A | VAL287 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 302 |
| Chain | Residue |
| A | GLN167 |
| A | PRO229 |
| A | VAL230 |
| A | ASN254 |
| A | HOH428 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 303 |
| Chain | Residue |
| A | SER37 |
| A | THR38 |
| A | LYS39 |
| A | ARG40 |
| A | HOH645 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | binding site for residue MES A 304 |
| Chain | Residue |
| A | GLY14 |
| A | SER15 |
| A | TRP16 |
| A | TYR17 |
| A | THR18 |
| A | GLY51 |
| A | TYR52 |
| A | THR53 |
| A | TYR54 |
| A | GSH301 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 305 |
| Chain | Residue |
| A | LYS108 |
| A | GLU112 |
| A | LYS175 |
| A | TYR176 |
| A | HOH402 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 306 |
| Chain | Residue |
| A | ASN25 |
| A | GLU29 |
| A | LYS142 |
| A | GLU145 |
| A | HOH451 |
| A | HOH493 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 307 |
| Chain | Residue |
| A | SER277 |
| A | ASP284 |
| A | SER285 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue PEG A 308 |
| Chain | Residue |
| A | LYS218 |
| A | MET221 |
| A | SER222 |
| A | LEU271 |
| A | ASN272 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 309 |
| site_id | AD1 |
| Number of Residues | 1 |
| Details | binding site for residue EDO A 310 |
| site_id | AD2 |
| Number of Residues | 18 |
| Details | binding site for residue GSH B 301 |
| Chain | Residue |
| B | SER15 |
| B | TRP16 |
| B | HIS49 |
| B | ALA50 |
| B | GLY51 |
| B | TYR54 |
| B | ASP189 |
| B | HIS192 |
| B | VAL287 |
| B | TYR289 |
| B | EDO310 |
| B | HOH402 |
| B | HOH559 |
| B | HOH565 |
| B | HOH590 |
| B | HOH633 |
| C | SER15 |
| C | GSH511 |
| site_id | AD3 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 302 |
| Chain | Residue |
| B | GLU112 |
| B | THR116 |
| B | LYS175 |
| B | HOH431 |
| B | HOH445 |
| B | HOH475 |
| B | HOH577 |
| site_id | AD4 |
| Number of Residues | 7 |
| Details | binding site for residue GOL B 303 |
| Chain | Residue |
| B | GLU163 |
| B | GLU166 |
| B | GLN167 |
| B | PRO229 |
| B | SER233 |
| B | ASN254 |
| B | HOH516 |
| site_id | AD5 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 304 |
| Chain | Residue |
| B | ARG211 |
| B | GLU214 |
| B | HIS215 |
| B | HOH523 |
| site_id | AD6 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 305 |
| Chain | Residue |
| B | HOH605 |
| B | PHE270 |
| B | LEU271 |
| site_id | AD7 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 306 |
| Chain | Residue |
| B | LYS218 |
| B | SER222 |
| B | GLU225 |
| B | PHE270 |
| B | HOH543 |
| site_id | AD8 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 307 |
| Chain | Residue |
| B | HIS131 |
| B | HOH427 |
| B | HOH441 |
| C | EDO512 |
| C | HOH701 |
| C | HOH787 |
| site_id | AD9 |
| Number of Residues | 2 |
| Details | binding site for residue EDO B 308 |
| Chain | Residue |
| B | TYR239 |
| B | HIS240 |
| site_id | AE1 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 309 |
| Chain | Residue |
| B | ASN25 |
| B | HOH413 |
| B | HOH570 |
| site_id | AE2 |
| Number of Residues | 8 |
| Details | binding site for residue EDO B 310 |
| Chain | Residue |
| B | SER15 |
| B | TRP16 |
| B | GLY51 |
| B | TYR52 |
| B | THR53 |
| B | TYR54 |
| B | GSH301 |
| B | HOH559 |
| site_id | AE3 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 311 |
| Chain | Residue |
| B | TRP114 |
| B | GLY117 |
| B | PHE119 |
| B | HOH420 |
| site_id | AE4 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 312 |
| Chain | Residue |
| B | TRP114 |
| B | ARG121 |
| B | HOH581 |
| site_id | AE5 |
| Number of Residues | 5 |
| Details | binding site for residue GOL C 501 |
| Chain | Residue |
| C | GLU166 |
| C | GLN167 |
| C | PRO229 |
| C | ASN254 |
| C | HOH706 |
| site_id | AE6 |
| Number of Residues | 5 |
| Details | binding site for residue EDO C 502 |
| Chain | Residue |
| C | ASP284 |
| C | SER285 |
| C | HOH606 |
| C | HOH636 |
| C | HOH660 |
| site_id | AE7 |
| Number of Residues | 7 |
| Details | binding site for residue EDO C 503 |
| Chain | Residue |
| C | SER15 |
| C | TRP16 |
| C | GLY51 |
| C | TYR52 |
| C | THR53 |
| C | GSH511 |
| C | HOH816 |
| site_id | AE8 |
| Number of Residues | 4 |
| Details | binding site for residue PEG C 504 |
| Chain | Residue |
| C | ARG87 |
| C | TRP114 |
| C | GLY117 |
| C | PHE119 |
| site_id | AE9 |
| Number of Residues | 3 |
| Details | binding site for residue EDO C 505 |
| Chain | Residue |
| C | MET221 |
| C | LEU271 |
| C | HOH817 |
| site_id | AF1 |
| Number of Residues | 6 |
| Details | binding site for residue EDO C 506 |
| Chain | Residue |
| C | ARG246 |
| C | HIS247 |
| C | HOH609 |
| C | HOH618 |
| C | HOH775 |
| C | HOH842 |
| site_id | AF2 |
| Number of Residues | 2 |
| Details | binding site for residue EDO C 507 |
| site_id | AF3 |
| Number of Residues | 3 |
| Details | binding site for residue EDO C 508 |
| Chain | Residue |
| C | GLU214 |
| C | HIS215 |
| C | HOH725 |
| site_id | AF4 |
| Number of Residues | 5 |
| Details | binding site for residue EDO C 509 |
| Chain | Residue |
| C | SER37 |
| C | THR38 |
| C | LYS39 |
| C | ARG40 |
| C | HOH751 |
| site_id | AF5 |
| Number of Residues | 3 |
| Details | binding site for residue EDO C 510 |
| Chain | Residue |
| C | ARG4 |
| C | SER92 |
| C | ARG121 |
| site_id | AF6 |
| Number of Residues | 17 |
| Details | binding site for residue GSH C 511 |
| Chain | Residue |
| B | SER15 |
| B | GSH301 |
| B | HOH546 |
| C | SER15 |
| C | TRP16 |
| C | HIS49 |
| C | ALA50 |
| C | GLY51 |
| C | TYR54 |
| C | ASP189 |
| C | HIS192 |
| C | VAL287 |
| C | TYR289 |
| C | EDO503 |
| C | HOH610 |
| C | HOH705 |
| C | HOH843 |
| site_id | AF7 |
| Number of Residues | 6 |
| Details | binding site for residue EDO C 512 |
| Chain | Residue |
| B | EDO307 |
| B | HOH501 |
| B | HOH526 |
| C | HIS131 |
| C | HOH603 |
| C | HOH614 |
| site_id | AF8 |
| Number of Residues | 22 |
| Details | binding site for residue GSH D 301 |
| Chain | Residue |
| A | SER15 |
| A | TRP16 |
| A | GSH301 |
| A | HOH425 |
| A | HOH439 |
| D | SER15 |
| D | TRP16 |
| D | HIS49 |
| D | ALA50 |
| D | GLY51 |
| D | TYR54 |
| D | ASP189 |
| D | HIS192 |
| D | VAL287 |
| D | TYR289 |
| D | MES306 |
| D | HOH406 |
| D | HOH408 |
| D | HOH495 |
| D | HOH497 |
| D | HOH645 |
| D | HOH657 |
| site_id | AF9 |
| Number of Residues | 5 |
| Details | binding site for residue EDO D 302 |
| Chain | Residue |
| D | SER37 |
| D | THR38 |
| D | LYS39 |
| D | ARG40 |
| D | HOH550 |
| site_id | AG1 |
| Number of Residues | 3 |
| Details | binding site for residue PEG D 303 |
| Chain | Residue |
| D | SER222 |
| D | GLU225 |
| D | LEU271 |
| site_id | AG2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO D 304 |
| Chain | Residue |
| D | SER277 |
| D | ASP284 |
| D | SER285 |
| D | HOH424 |
| D | HOH428 |
| D | HOH442 |
| site_id | AG3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO D 305 |
| Chain | Residue |
| D | HIS192 |
| D | THR242 |
| D | SER244 |
| D | ARG246 |
| D | HOH458 |
| site_id | AG4 |
| Number of Residues | 9 |
| Details | binding site for residue MES D 306 |
| Chain | Residue |
| D | GLY14 |
| D | SER15 |
| D | TRP16 |
| D | THR18 |
| D | GLY51 |
| D | TYR52 |
| D | THR53 |
| D | TYR54 |
| D | GSH301 |
| site_id | AG5 |
| Number of Residues | 9 |
| Details | binding site for residue MES D 307 |
| Chain | Residue |
| C | TYR202 |
| C | GLU208 |
| C | ARG280 |
| C | TRP282 |
| D | TRP31 |
| D | GLN34 |
| D | HOH594 |
| D | HOH601 |
| D | HOH642 |
| site_id | AG6 |
| Number of Residues | 2 |
| Details | binding site for residue EDO D 308 |
| Chain | Residue |
| D | ASP94 |
| D | GLN107 |
| site_id | AG7 |
| Number of Residues | 7 |
| Details | binding site for residue GOL D 309 |
| Chain | Residue |
| D | GLU163 |
| D | GLU166 |
| D | GLN167 |
| D | VAL230 |
| D | ASN254 |
| D | HOH402 |
| D | HOH526 |
| site_id | AG8 |
| Number of Residues | 4 |
| Details | binding site for residue EDO D 310 |
| Chain | Residue |
| D | SER37 |
| D | ARG40 |
| D | LYS64 |
| D | HOH623 |
| site_id | AG9 |
| Number of Residues | 3 |
| Details | binding site for residue EDO D 311 |
| Chain | Residue |
| D | ALA19 |
| D | SER20 |
| D | HOH485 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"Q91VH6","evidenceCode":"ECO:0000250"}]} |
