5WKP

Crystal Structure of the Human mitochondrial Cysteine Desulfurase in complex with ISD11 and Iron-Sulfur Cluster Scaffold Protein ISCU1, and E. coli ACP1 protein at 3.15A

Summary for 5WKP

Entry DOI	10.2210/pdb5wkp/pdb
Related	5WLW
Descriptor	Cysteine desulfurase, mitochondrial, LYR motif-containing protein 4, Acyl carrier protein, ... (6 entities in total)
Functional Keywords	human mitochondrial cysteine desulfurse lyr motif containing protein 4 iron-sulfur cluster scaffold protein iscu1 acyl carrier protein 1 (e.coli), transferase
Biological source	Homo sapiens (Human) More
Cellular location	Isoform Mitochondrial: Mitochondrion. Isoform Cytoplasmic: Cytoplasm: Q9Y697 Mitochondrion: Q9HD34 Cytoplasm : B7MJ81 Isoform 1: Mitochondrion . Isoform 2: Cytoplasm: Q9H1K1
Total number of polymer chains	8
Total formula weight	162969.87
Authors	Boniecki, M.T.,Cygler, M. (deposition date: 2017-07-25, release date: 2017-11-15, Last modification date: 2023-10-04)
Primary citation	Boniecki, M.T.,Freibert, S.A.,Muhlenhoff, U.,Lill, R.,Cygler, M. Structure and functional dynamics of the mitochondrial Fe/S cluster synthesis complex. Nat Commun, 8:1287-1287, 2017 Cited by PubMed: 29097656 DOI: 10.1038/s41467-017-01497-1 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.15 Å)

Structure validation