6UXE

Structure of the human mitochondrial desulfurase complex Nfs1-ISCU2(M140I)-ISD11 with E.coli ACP1 at 1.57 A resolution showing flexibility of N terminal end of ISCU2

Summary for 6UXE

• Entry DOI: 10.2210/pdb6uxe/pdb
• Descriptor: Cysteine desulfurase, mitochondrial, 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ... (17 entities in total)
• Functional Keywords: human mitochondrial cysteine desulfurase complex, transferase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 87651.82

Authors

Boniecki, M.T.,Cygler, M. (deposition date: 2019-11-07, release date: 2019-11-20, Last modification date: 2023-10-11)

• Primary citation: Freibert, S.A.,Boniecki, M.T.,Shulz, V.,Wilbrecht, C.,Krapoth, N.,Muhlenhoff, U.,Stehling, O.,Cygler, M.,Lill, R.; The essential function of ISCU2 and its conserved N-terminus in Fe/S cluster biogenesis; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.57 Å)