6UXE

Structure of the human mitochondrial desulfurase complex Nfs1-ISCU2(M140I)-ISD11 with E.coli ACP1 at 1.57 A resolution showing flexibility of N terminal end of ISCU2

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0030170	molecular_function	pyridoxal phosphate binding
A	0031071	molecular_function	cysteine desulfurase activity
A	0044571	biological_process	[2Fe-2S] cluster assembly
B	0005198	molecular_function	structural molecule activity
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005739	cellular_component	mitochondrion
B	0005759	cellular_component	mitochondrial matrix
B	0016226	biological_process	iron-sulfur cluster assembly
B	0016604	cellular_component	nuclear body
B	0042803	molecular_function	protein homodimerization activity
B	0044571	biological_process	[2Fe-2S] cluster assembly
B	0044572	biological_process	[4Fe-4S] cluster assembly
B	0060090	molecular_function	molecular adaptor activity
B	0099128	cellular_component	mitochondrial [2Fe-2S] assembly complex
B	1990221	cellular_component	L-cysteine desulfurase complex
B	1990229	cellular_component	iron-sulfur cluster assembly complex
C	0000035	molecular_function	acyl binding
C	0000036	molecular_function	acyl carrier activity
C	0005515	molecular_function	protein binding
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006629	biological_process	lipid metabolic process
C	0006631	biological_process	fatty acid metabolic process
C	0006633	biological_process	fatty acid biosynthetic process
C	0008289	molecular_function	lipid binding
C	0008610	biological_process	lipid biosynthetic process
C	0009245	biological_process	lipid A biosynthetic process
C	0009410	biological_process	response to xenobiotic stimulus
C	0016020	cellular_component	membrane
C	0031177	molecular_function	phosphopantetheine binding
D	0005506	molecular_function	iron ion binding
D	0016226	biological_process	iron-sulfur cluster assembly
D	0051536	molecular_function	iron-sulfur cluster binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	16
Details	binding site for residue PLP A 501

Chain	Residue
A	GLY126
A	SER255
A	HIS257
A	LYS258
A	THR295
A	CYS381
A	HOH636
A	HOH776
A	ALA127
A	THR128
A	HIS156
A	MET203
A	ASN207
A	ASP232
A	ALA234
A	GLN235

---

site_id	AC2
Number of Residues	10
Details	binding site for residue GOL A 502

Chain	Residue
A	PRO58
A	THR92
A	HIS93
A	ALA94
A	LEU367
A	MET368
A	LEU370
A	LYS371
A	EDO509
D	TYR35

---

site_id	AC3
Number of Residues	5
Details	binding site for residue GOL A 503

Chain	Residue
A	ARG321
A	THR415
A	GLU416
A	GLU417
B	ARG34

---

site_id	AC4
Number of Residues	6
Details	binding site for residue GOL A 504

Chain	Residue
A	LYS431
A	ARG434
A	GLU435
A	TRP440
A	HOH678
A	HOH801

---

site_id	AC5
Number of Residues	7
Details	binding site for residue GOL A 505

Chain	Residue
A	GLU190
A	ARG220
A	ILE221
A	SER224
A	ARG225
A	HOH619
A	HOH633

---

site_id	AC6
Number of Residues	7
Details	binding site for residue EDO A 506

Chain	Residue
A	GLN179
A	ASP185
A	LYS371
A	ARG432
A	EDO507
A	EDO530
D	GLU44

---

site_id	AC7
Number of Residues	9
Details	binding site for residue EDO A 507

Chain	Residue
A	MET368
A	ALA369
A	LYS371
A	HIS429
A	EDO506
A	EDO530
D	VAL40
D	TYR43
D	GLU44

---

site_id	AC8
Number of Residues	4
Details	binding site for residue EDO A 508

Chain	Residue
A	MET334
A	LYS335
A	LEU337
A	PRO338

---

site_id	AC9
Number of Residues	5
Details	binding site for residue EDO A 509

Chain	Residue
A	PRO58
A	LYS371
A	GOL502
A	HOH624
A	HOH698

---

site_id	AD1
Number of Residues	4
Details	binding site for residue EDO A 510

Chain	Residue
A	LYS157
A	TYR390
A	PEG527
A	HOH653

---

site_id	AD2
Number of Residues	5
Details	binding site for residue EDO A 511

Chain	Residue
A	ARG105
A	GLN108
A	EDO517
A	HOH617
A	HOH781

---

site_id	AD3
Number of Residues	5
Details	binding site for residue EDO A 512

Chain	Residue
A	GLU100
A	ALA101
A	HOH617
A	HOH671
A	HOH800

---

site_id	AD4
Number of Residues	6
Details	binding site for residue EDO A 513

Chain	Residue
A	SER223
A	LYS248
A	ASP250
A	ARG271
A	GOL551
A	HOH609

---

site_id	AD5
Number of Residues	8
Details	binding site for residue EDO A 514

Chain	Residue
A	SER125
A	ARG292
A	THR295
A	PRO297
A	HOH636
A	HOH675
A	HOH675
A	HOH682

---

site_id	AD6
Number of Residues	4
Details	binding site for residue EDO A 515

Chain	Residue
A	HOH710
B	PEG104
A	GLU316
A	LYS320

---

site_id	AD7
Number of Residues	6
Details	binding site for residue EDO A 516

Chain	Residue
A	GLN179
A	SER181
A	ASP345
A	HOH604
A	HOH610
D	ASN45

---

site_id	AD8
Number of Residues	6
Details	binding site for residue EDO A 517

Chain	Residue
A	GLU104
A	GLN108
A	PRO118
A	EDO511
A	HOH651
A	HOH762

---

site_id	AD9
Number of Residues	8
Details	binding site for residue PEG A 518

Chain	Residue
A	ASP75
A	PRO79
A	HOH841
B	ARG68
B	LEU75
B	TYR76
B	SER77
B	HOH218

---

site_id	AE1
Number of Residues	10
Details	binding site for residue PG4 A 519

Chain	Residue
A	SER112
A	GLY115
A	ALA116
A	GLN312
A	GLN313
A	EDO525
A	PEG550
A	HOH645
A	HOH745
A	HOH753

---

site_id	AE2
Number of Residues	4
Details	binding site for residue PG4 A 520

Chain	Residue
A	ARG328
A	ASN332
A	HOH667
A	HOH670

---

site_id	AE3
Number of Residues	1
Details	binding site for residue PEG A 521

Chain	Residue
A	HIS319

---

site_id	AE4
Number of Residues	6
Details	binding site for residue EDO A 522

Chain	Residue
A	ALA359
A	TYR360
A	ASP400
A	SER404
A	LEU439
A	P15526

---

site_id	AE5
Number of Residues	5
Details	binding site for residue EDO A 523

Chain	Residue
A	ARG220
A	SER224
A	LYS248
D	ARG89
D	EDO202

---

site_id	AE6
Number of Residues	2
Details	binding site for residue EDO A 524

Chain	Residue
A	ARG119
A	ARG272

---

site_id	AE7
Number of Residues	3
Details	binding site for residue EDO A 525

Chain	Residue
A	GLN312
A	GLN313
A	PG4519

---

site_id	AE8
Number of Residues	13
Details	binding site for residue P15 A 526

Chain	Residue
A	LEU337
A	PRO338
A	ASP339
A	VAL340
A	VAL341
A	ALA359
A	ASP400
A	LEU401
A	LEU449
A	EDO522
A	HOH612
A	HOH615
A	HOH729

---

site_id	AE9
Number of Residues	4
Details	binding site for residue PEG A 527

Chain	Residue
A	GLN153
A	TYR175
A	EDO510
A	PEG531

---

site_id	AF1
Number of Residues	4
Details	binding site for residue EDO A 528

Chain	Residue
A	GLN108
A	ASP117
A	PRO118
A	HOH634

---

site_id	AF2
Number of Residues	3
Details	binding site for residue EDO A 529

Chain	Residue
A	GLN313
A	EDO545
B	ARG35

---

site_id	AF3
Number of Residues	7
Details	binding site for residue EDO A 530

Chain	Residue
A	LYS371
A	LYS425
A	GLN428
A	HIS429
A	EDO506
A	EDO507
A	HOH601

---

site_id	AF4
Number of Residues	5
Details	binding site for residue PEG A 531

Chain	Residue
A	GLU167
A	VAL173
A	THR174
A	TYR175
A	PEG527

---

site_id	AF5
Number of Residues	2
Details	binding site for residue PEG A 532

Chain	Residue
A	GLN331
A	PGE534

---

site_id	AF6
Number of Residues	7
Details	binding site for residue DTT A 533

Chain	Residue
A	GLU120
A	VAL244
A	ASN245
A	TYR269
A	ARG271
A	ARG273
A	PEG550

---

site_id	AF7
Number of Residues	11
Details	binding site for residue PGE A 534

Chain	Residue
A	HIS319
A	SER323
A	SER326
A	ILE330
A	PRO346
A	HIS349
A	PRO351
A	PEG532
A	EDO552
A	HOH602
A	HOH607

---

site_id	AF8
Number of Residues	4
Details	binding site for residue EDO A 535

Chain	Residue
A	GLU416
A	GLU417
A	ASP420
A	HOH727

---

site_id	AF9
Number of Residues	6
Details	binding site for residue EDO A 536

Chain	Residue
A	GLU217
A	ARG220
A	HOH659
A	HOH819
D	ARG47
D	ASN48

---

site_id	AG1
Number of Residues	3
Details	binding site for residue EDO A 537

Chain	Residue
A	ASP420
A	TYR421
A	HOH727

---

site_id	AG2
Number of Residues	6
Details	binding site for residue EDO A 538

Chain	Residue
A	LYS212
A	GLN213
A	HOH647
A	HOH649
A	HOH659
A	HOH740

---

site_id	AG3
Number of Residues	4
Details	binding site for residue EDO A 539

Chain	Residue
A	LYS180
A	ARG393
A	ALA394
A	HOH662

---

site_id	AG4
Number of Residues	2
Details	binding site for residue EDO A 540

Chain	Residue
A	PHE141
A	EDO542

---

site_id	AG5
Number of Residues	4
Details	binding site for residue EDO A 541

Chain	Residue
A	GLN428
A	ARG432
A	HOH608
A	HOH771

---

site_id	AG6
Number of Residues	5
Details	binding site for residue EDO A 542

Chain	Residue
A	PHE141
A	TYR142
A	ARG143
A	SER144
A	EDO540

---

site_id	AG7
Number of Residues	11
Details	binding site for residue PGE A 543

Chain	Residue
A	ARG105
A	GLN109
A	ALA306
A	GLU309
A	VAL310
A	GLN313
A	HOH646
A	HOH680
B	ARG61
B	HOH221
B	HOH260

---

site_id	AG8
Number of Residues	2
Details	binding site for residue PGE A 544

Chain	Residue
A	ARG105
A	HOH614

---

site_id	AG9
Number of Residues	4
Details	binding site for residue EDO A 545

Chain	Residue
A	GLU314
A	EDO529
A	HOH742
B	ARG35

---

site_id	AH1
Number of Residues	6
Details	binding site for residue EDO A 546

Chain	Residue
A	ILE270
A	ARG271
A	ARG272
A	ARG275
A	VAL276
A	HOH605

---

site_id	AH2
Number of Residues	4
Details	binding site for residue EDO A 547

Chain	Residue
A	GLY286
A	GLN287
A	EDO553
A	HOH754

---

site_id	AH3
Number of Residues	2
Details	binding site for residue PEG A 548

Chain	Residue
A	GLU441
A	MET442

---

site_id	AH4
Number of Residues	5
Details	binding site for residue PEG A 549

Chain	Residue
A	ASP161
A	SER283
A	GLY284
A	EDO554
A	HOH722

---

site_id	AH5
Number of Residues	8
Details	binding site for residue PEG A 550

Chain	Residue
A	GLY115
A	ALA116
A	ASP117
A	ASP243
A	PG4519
A	DTT533
A	HOH634
A	HOH677

---

site_id	AH6
Number of Residues	7
Details	binding site for residue GOL A 551

Chain	Residue
A	SER223
A	LYS226
A	VAL227
A	ASP250
A	EDO513
A	HOH621
A	HOH637

---

site_id	AH7
Number of Residues	8
Details	binding site for residue EDO A 552

Chain	Residue
A	LYS212
A	PRO346
A	LYS347
A	HIS348
A	HIS349
A	PGE534
A	HOH607
A	HOH740

---

site_id	AH8
Number of Residues	7
Details	binding site for residue EDO A 553

Chain	Residue
A	GLY286
A	GLN287
A	GLU288
A	ARG289
A	EDO547
A	HOH717
A	HOH824

---

site_id	AH9
Number of Residues	9
Details	binding site for residue EDO A 554

Chain	Residue
A	ALA280
A	GLN282
A	GLY284
A	GLY290
A	MET291
A	ARG292
A	SER293
A	PEG549
A	HOH782

---

site_id	AI1
Number of Residues	7
Details	binding site for residue EDO B 101

Chain	Residue
A	VAL63
A	PRO68
A	TYR85
A	PHE413
A	HOH721
B	ASN27
B	HOH202

---

site_id	AI2
Number of Residues	7
Details	binding site for residue EDO B 102

Chain	Residue
A	ASP445
B	ALA11
B	LEU12
B	HOH208
B	HOH220
B	HOH255
B	HOH257

---

site_id	AI3
Number of Residues	4
Details	binding site for residue EDO B 103

Chain	Residue
B	ARG18
B	ARG22
B	HOH224
B	HOH226

---

site_id	AI4
Number of Residues	7
Details	binding site for residue PEG B 104

Chain	Residue
A	TYR317
A	EDO515
B	ARG35
B	ASP38
B	ALA39
B	GLU42
B	HOH245

---

site_id	AI5
Number of Residues	5
Details	binding site for residue EDO B 105

Chain	Residue
A	ASP445
A	GLY446
B	ARG67
B	PEG106
B	EDO107

---

site_id	AI6
Number of Residues	5
Details	binding site for residue PEG B 106

Chain	Residue
B	ARG67
B	ARG68
B	LEU75
B	EDO105
B	EDO107

---

site_id	AI7
Number of Residues	8
Details	binding site for residue EDO B 107

Chain	Residue
A	GLY446
B	GLY64
B	ARG67
B	ARG68
B	EDO105
B	PEG106
B	HOH201
B	HOH242

---

site_id	AI8
Number of Residues	2
Details	binding site for residue EDO B 108

Chain	Residue
B	GLU42
B	ASN43

---

site_id	AI9
Number of Residues	5
Details	binding site for residue EDO B 109

Chain	Residue
B	LYS21
B	ARG22
B	PHE23
B	ARG29
B	EDT110

---

site_id	AJ1
Number of Residues	9
Details	binding site for residue EDT B 110

Chain	Residue
A	GLU417
B	LYS21
B	TYR26
B	ARG29
B	LYS80
B	ILE83
B	GLU84
B	EDO109
B	HOH231

---

site_id	AJ2
Number of Residues	4
Details	binding site for residue EDO B 111

Chain	Residue
A	ILE193
A	ARG225
B	HOH206
B	HOH251

---

site_id	AJ3
Number of Residues	7
Details	binding site for residue EDO B 112

Chain	Residue
A	LYS187
A	GLU190
A	GLU435
A	HOH628
B	ALA2
B	ALA3
B	HOH235

---

site_id	AJ4
Number of Residues	13
Details	binding site for residue 8Q1 C 301

Chain	Residue
B	ARG6
B	VAL9
B	ALA39
B	PHE40
B	ASN43
B	LYS44
B	VAL46
B	ILE52
B	HOH243
C	ASP35
C	SER36
C	EDO303
C	HOH415

---

site_id	AJ5
Number of Residues	6
Details	binding site for residue MES C 302

Chain	Residue
B	ARG41
B	LYS44
C	LEU15
C	GLY33
C	ASP35
C	ASP38

---

site_id	AJ6
Number of Residues	5
Details	binding site for residue EDO C 303

Chain	Residue
C	VAL29
C	ASP35
C	SER36
C	8Q1301
C	HOH401

---

site_id	AJ7
Number of Residues	4
Details	binding site for residue EDO C 304

Chain	Residue
C	GLN14
C	ASP38
C	GLU41
C	LEU42

---

site_id	AJ8
Number of Residues	5
Details	binding site for residue PEG C 305

Chain	Residue
B	LYS21
C	GLN14
C	GLU41
C	MET44
C	GLU48

---

site_id	AJ9
Number of Residues	3
Details	binding site for residue EDO C 306

Chain	Residue
C	TYR71
C	HIS75
D	LYS57

---

site_id	AK1
Number of Residues	7
Details	binding site for residue EDO D 201

Chain	Residue
A	GLU441
A	HOH628
A	HOH633
D	GLY50
D	SER51
D	LYS91
D	EDO202

---

site_id	AK2
Number of Residues	6
Details	binding site for residue EDO D 202

Chain	Residue
A	ARG220
A	EDO523
D	GLY50
D	SER51
D	ARG89
D	EDO201

---

site_id	AK3
Number of Residues	7
Details	binding site for residue 1PE D 203

Chain	Residue
D	TRP108
D	GLY111
D	LYS112
D	GLU116
D	THR119
D	ILE120
D	HOH312

---

site_id	AK4
Number of Residues	2
Details	binding site for residue EDO D 204

Chain	Residue
D	THR61
D	ASP152

---

site_id	AK5
Number of Residues	6
Details	binding site for residue GOL D 205

Chain	Residue
B	ARG14
C	ASP56
D	ASP53
D	THR55
D	HOH305
D	HOH320

---

site_id	AK6
Number of Residues	2
Details	binding site for residue EDO D 206

Chain	Residue
D	ASP80
D	HOH302

---

site_id	AK7
Number of Residues	3
Details	binding site for residue EDO D 207

Chain	Residue
D	GLU107
D	HOH321
D	HOH336

---

Functional Information from PROSITE/UniProt

site_id	PS00012
Number of Residues	16
Details	PHOSPHOPANTETHEINE Phosphopantetheine attachment site. DLGADSLDTVELVMAL

Chain	Residue	Details
C	ASP31-LEU46

---

site_id	PS00595
Number of Residues	20
Details	AA_TRANSFER_CLASS_5 Aminotransferases class-V pyridoxal-phosphate attachment site. IDLMsiSGHKiygpk.GvGaI

Chain	Residue	Details
A	ILE249-ILE268

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"description":"Cysteine persulfide intermediate","evidences":[{"source":"PubMed","id":"18650437","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"23593335","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"29097656","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34824239","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5WKP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WLW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6UXE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6W1D","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6WI2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6WIH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7RTK","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"29097656","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31101807","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34824239","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5WKP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WLW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6NZU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6UXE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6W1D","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6WI2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6WIH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7RTK","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"29097656","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31101807","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5WKP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WLW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6NZU","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"29097656","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5WLW","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	Modified residue: {"description":"N6-(pyridoxal phosphate)lysine","evidences":[{"source":"PubMed","id":"29097656","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31101807","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34824239","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5WKP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WLW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6NZU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6UXE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6W1D","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6WI2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6WIH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7RTK","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	1
Details	Modified residue: {"description":"Cysteine persulfide","evidences":[{"source":"PubMed","id":"18650437","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"23593335","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"31664822","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6ODD","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"Q8K215","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	1
Details	Modified residue: {"description":"O-(pantetheine 4'-phosphoryl)serine","evidences":[{"source":"PROSITE-ProRule","id":"PRU00258","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"4882207","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	1
Details	Active site: {"description":"Cysteine persulfide intermediate","evidences":[{"source":"UniProtKB","id":"Q9D7P6","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	1
Details	Active site: {"description":"Cysteine persulfide intermediate","evidences":[{"source":"UniProtKB","id":"O29689","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PubMed","id":"31101807","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6NZU","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	1
Details	Site: {"description":"Mediates ISCU dimerization and de novo [2Fe-2S] cluster assembly","evidences":[{"source":"PubMed","id":"34824239","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	1
Details	Modified residue: {"description":"Cysteine persulfide","evidences":[{"source":"UniProtKB","id":"Q9D7P6","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI16
Number of Residues	1
Details	Modified residue: {"description":"Cysteine persulfide","evidences":[{"source":"PubMed","id":"24971490","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---