1LCJ

SH2 (SRC HOMOLOGY-2) DOMAIN OF HUMAN P56-LCK TYROSINE KINASE COMPLEXED WITH THE 11 RESIDUE PHOSPHOTYROSYL PEPTIDE EPQPYEEIPIYL

Summary for 1LCJ

DescriptorP56==LCK== TYROSINE KINASE, PHOSPHOPEPTIDE EPQ(PHOSPHO)YEEIPIYL (3 entities in total)
Functional Keywordscomplex (kinase-peptide), complex (kinase-peptide) complex, complex (kinase/peptide)
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm P06239
Host membrane; Single-pass membrane protein (Potential) P03079
Total number of polymer chains2
Total molecular weight13862.34
Authors
Eck, M.,Harrison, S. (deposition date: 1994-12-12, release date: 1995-10-15, Last modification date: 2011-07-13)
Primary citation
Eck, M.J.,Shoelson, S.E.,Harrison, S.C.
Recognition of a high-affinity phosphotyrosyl peptide by the Src homology-2 domain of p56lck.
Nature, 362:87-91, 1993
PubMed: 7680435 (PDB entries with the same primary citation)
DOI: 10.1038/362087a0
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.8 Å)
NMR Information
?

Structure validation

ClashscoreRamachandran outliersSidechain outliers40.9%6.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload