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PDB: 480 件

8A4I
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Crystal structure of SALL4 zinc finger cluster 4 with AT-rich DNA
分子名称: DNA (5'-D(*GP*AP*TP*AP*TP*TP*AP*AP*TP*AP*TP*C)-3'), MAGNESIUM ION, Sal-like protein 4, ...
著者Watson, J.A, Pantier, R, Jayachandran, U, Chhatbar, K, Alexander-Howden, B, Kruusvee, V, Prendecki, M, Bird, A, Cook, A.G.
登録日2022-06-11
公開日2023-01-11
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献Structure of SALL4 zinc finger domain reveals link between AT-rich DNA binding and Okihiro syndrome.
Life Sci Alliance, 6, 2023
4V7E
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Model of the small subunit RNA based on a 5.5 A cryo-EM map of Triticum aestivum translating 80S ribosome
分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S10E, ...
著者Barrio-Garcia, C, Armache, J.-P, Jarasch, A, Anger, A.M, Villa, E, Becker, T, Bhushan, S, Jossinet, F, Habeck, M, Dindar, G, Franckenberg, S, Marquez, V, Mielke, T, Thomm, M, Berninghausen, O, Beatrix, B, Soeding, J, Westhof, E, Wilson, D.N, Beckmann, R.
登録日2013-11-22
公開日2014-07-09
最終更新日2023-02-01
実験手法ELECTRON MICROSCOPY (5.5 Å)
主引用文献Structures of the Sec61 complex engaged in nascent peptide translocation or membrane insertion.
Nature, 506, 2014
7STE
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Rad24-RFC ADP state
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Checkpoint protein RAD24, ...
著者Castaneda, J.C, Schrecker, M, Remus, D, Hite, R.K.
登録日2021-11-12
公開日2022-04-06
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.73 Å)
主引用文献Mechanisms of loading and release of the 9-1-1 checkpoint clamp.
Nat.Struct.Mol.Biol., 29, 2022
4YE0
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Stress-induced protein 1 truncation mutant (43 - 140) from Caenorhabditis elegans
分子名称: SULFATE ION, Stress-induced protein 1
著者Fleckenstein, T, Kastenmueller, A, Stein, M.L, Peters, C, Daake, M, Krause, M, Weinfurtner, D, Haslbeck, M, Weinkauf, S, Groll, M, Buchner, J.
登録日2015-02-23
公開日2015-06-10
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The Chaperone Activity of the Developmental Small Heat Shock Protein Sip1 Is Regulated by pH-Dependent Conformational Changes.
Mol.Cell, 58, 2015
4YDZ
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Stress-induced protein 1 from Caenorhabditis elegans
分子名称: Stress-induced protein 1
著者Fleckenstein, T, Kastenmueller, A, Stein, M.L, Peters, C, Daake, M, Krause, M, Weinfurtner, D, Haslbeck, M, Weinkauf, S, Groll, M, Buchner, J.
登録日2015-02-23
公開日2015-06-10
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献The Chaperone Activity of the Developmental Small Heat Shock Protein Sip1 Is Regulated by pH-Dependent Conformational Changes.
Mol.Cell, 58, 2015
3IZD
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Model of the large subunit RNA expansion segment ES27L-out based on a 6.1 A cryo-EM map of Saccharomyces cerevisiae translating 80S ribosome. 3IZD is a small part (an expansion segment) which is in an alternative conformation to what is in already 3IZF.
分子名称: rRNA expansion segment ES27L in an "out" conformation
著者Armache, J.-P, Jarasch, A, Anger, A.M, Villa, E, Becker, T, Bhushan, S, Jossinet, F, Habeck, M, Dindar, G, Franckenberg, S, Marquez, V, Mielke, T, Thomm, M, Berninghausen, O, Beatrix, B, Soeding, J, Westhof, E, Wilson, D.N, Beckmann, R.
登録日2010-10-13
公開日2010-12-01
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (8.6 Å)
主引用文献Cryo-EM structure and rRNA model of a translating eukaryotic 80S ribosome at 5.5-A resolution.
Proc.Natl.Acad.Sci.USA, 107, 2010
8A6M
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Phosphatidylserine-dependent synaptic vesicle membrane sculpting by synaptogyrin
分子名称: Isoform 1B of Synaptogyrin-1
著者Yu, T.K, Eastep, G.N, Flores, D, Zweckstetter, M.
登録日2022-06-18
公開日2023-05-24
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Phosphatidylserine-dependent structure of synaptogyrin remodels the synaptic vesicle membrane.
Nat.Struct.Mol.Biol., 30, 2023
8S03
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NMR solution structure of the CysD2 domain of MUC2
分子名称: CALCIUM ION, Mucin-2
著者Recktenwald, C, Karlsson, B.G, Garcia-Bonnete, M.-J, Katona, G, Jensen, M, Lymer, R, Baeckstroem, M, Johansson, M.E.V, Hansson, G.C, Trillo-Muyo, S.
登録日2024-02-13
公開日2024-04-17
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The structure of the second CysD domain of MUC2 and role in mucin organization by transglutaminase-based cross-linking.
Cell Rep, 43, 2024
8BGU
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human MDM2-5S RNP
分子名称: 5S rRNA, 60S ribosomal protein L11, 60S ribosomal protein L5, ...
著者Castillo, N, Thoms, M, Flemming, D, Hammaren, H.M, Buschauer, R, Ameismeier, M, Bassler, J, Beck, M, Beckmann, R, Hurt, E.
登録日2022-10-28
公開日2023-06-14
最終更新日2023-08-30
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structure of nascent 5S RNPs at the crossroad between ribosome assembly and MDM2-p53 pathways.
Nat.Struct.Mol.Biol., 30, 2023
5JDP
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E73V mutant of the human voltage-dependent anion channel
分子名称: Voltage-dependent anion-selective channel protein 1
著者Jaremko, M, Jaremko, L, Villinger, S, Schmidt, C, Giller, K, Griesinger, C, Becker, S, Zweckstetter, M.
登録日2016-04-17
公開日2016-08-10
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献High-Resolution NMR Determination of the Dynamic Structure of Membrane Proteins.
Angew.Chem.Int.Ed.Engl., 55, 2016
6P0X
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Structure of the N-terminal domain of effector protein SpvB from Salmonella typhimurium strain LT2
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACRYLIC ACID, GLYCEROL, ...
著者Xu, C, Boniecki, M, Cygler, M.
登録日2019-05-17
公開日2019-06-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of the N-terminal domain of effector protein SpvB from Salmonella typhimurium strain LT2
To Be Published
6MCQ
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L. pneumophila effector kinase LegK7 in complex with human MOB1A
分子名称: DI(HYDROXYETHYL)ETHER, HEXAETHYLENE GLYCOL, LegK7, ...
著者Beyrakhova, K.A, Xu, C, Boniecki, M.T, Cygler, M.
登録日2018-09-01
公開日2019-09-04
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献TheLegionellakinase LegK7 exploits the Hippo pathway scaffold protein MOB1A for allostery and substrate phosphorylation.
Proc.Natl.Acad.Sci.USA, 117, 2020
6MCP
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L. pneumophila effector kinase LegK7 (AMP-PNP bound) in complex with human MOB1A
分子名称: DI(HYDROXYETHYL)ETHER, HEXAETHYLENE GLYCOL, LegK7, ...
著者Beyrakhova, K.A, Xu, C, Boniecki, M.T, Cygler, M.
登録日2018-09-01
公開日2019-09-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献TheLegionellakinase LegK7 exploits the Hippo pathway scaffold protein MOB1A for allostery and substrate phosphorylation.
Proc.Natl.Acad.Sci.USA, 117, 2020
7ABT
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Structure of PPIA in complex with PR dipeptide repeat
分子名称: PRO-ARG-PRO-ARG-PRO-ARG-PRO-ARG, Peptidyl-prolyl cis-trans isomerase A
著者Babu, M, Zweckstetter, M, Becker, S.
登録日2020-09-08
公開日2021-06-23
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.31 Å)
主引用文献Proline/arginine dipeptide repeat polymers derail protein folding in amyotrophic lateral sclerosis.
Nat Commun, 12, 2021
1UTX
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Regulation of Cytolysin Expression by Enterococcus faecalis: Role of CylR2
分子名称: CYLR2, IODIDE ION, SODIUM ION
著者Razeto, A, Rumpel, S, Pillar, C.M, Gilmore, M.S, Becker, S, Zweckstetter, M.
登録日2003-12-12
公開日2004-09-16
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure and DNA-Binding Properties of the Cytolysin Regulator CylR2 from Enterococcus Faecalis
Embo J., 23, 2004
2JK4
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Structure of the human voltage-dependent anion channel
分子名称: VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL PROTEIN 1
著者Bayrhuber, M, Meins, T, Habeck, M, Becker, S, Giller, K, Villinger, S, Vonrhein, C, Griesinger, C, Zweckstetter, M, Zeth, K.
登録日2008-08-15
公開日2008-10-14
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (4.1 Å)
主引用文献Structure of the Human Voltage-Dependent Anion Channel.
Proc.Natl.Acad.Sci.USA, 105, 2008
7PQS
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SRPK1 in complex with MSC2711186
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, CITRIC ACID, ...
著者Schroeder, M, Leiendecker, M, Knapp, S, Structural Genomics Consortium (SGC)
登録日2021-09-20
公開日2021-12-15
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献SRPK1 in complex with MSC2711186
To Be Published
4FBL
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LipS and LipT, two metagenome-derived lipolytic enzymes increase the diversity of known lipase and esterase families
分子名称: CHLORIDE ION, LipS lipolytic enzyme, SPERMIDINE
著者Chow, J, Krauss, U, Dall Antonia, Y, Fersini, F, Schmeisser, C, Schmidt, M, Menyes, I, Bornscheuer, U, Lauinger, B, Bongen, P, Pietruszka, J, Eckstein, M, Thum, O, Liese, A, Mueller-Dieckmann, J, Jaeger, K.-E, Kovacic, F, Streit, W.R, Structural Proteomics in Europe (SPINE)
登録日2012-05-23
公開日2012-10-10
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献The Metagenome-Derived Enzymes LipS and LipT Increase the Diversity of Known Lipases.
Plos One, 7, 2012
6Y32
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Structure of the GTPase heterodimer of human SRP54 and SRalpha
分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, SULFATE ION, ...
著者Juaire, K.D, Becker, M.M.M, Wild, K, Sinning, I.
登録日2020-02-17
公開日2020-09-23
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural and Functional Impact of SRP54 Mutations Causing Severe Congenital Neutropenia.
Structure, 29, 2021
6Y31
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NG domain of human SRP54 T117 deletion mutant
分子名称: Signal recognition particle 54 kDa protein
著者Juaire, K.D, Lapouge, K, Becker, M.M.M, Kotova, I, Haas, M, Carapito, R, Wild, K, Bahram, S, Sinning, I.
登録日2020-02-17
公開日2020-09-23
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (4.001 Å)
主引用文献Structural and Functional Impact of SRP54 Mutations Causing Severe Congenital Neutropenia.
Structure, 29, 2021
2V9A
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Structure of Citrate-free Periplasmic Domain of Sensor Histidine Kinase CitA
分子名称: SENSOR KINASE CITA
著者Sevvana, M, Vijayan, V, Zweckstetter, M, Reinelt, S, Madden, D.R, Sheldrick, G.M, Bott, M, Griesinger, C, Becker, S.
登録日2007-08-23
公開日2008-03-25
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A Ligand-Induced Switch in the Periplasmic Domain of Sensor Histidine Kinase Cita.
J.Mol.Biol., 377, 2008
2CA7
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Conkunitzin-S1 Is The First Member Of A New Kunitz-Type Neurotoxin Family- Structural and Functional Characterization
分子名称: CONKUNITZIN-S1
著者Bayrhuber, M, Vijayan, V, Ferber, M, Graf, R, Korukottu, J, Imperial, J, Garrett, J.E, Olivera, B.M, Terlau, H, Zweckstetter, M, Becker, S.
登録日2005-12-19
公開日2006-01-05
最終更新日2020-01-15
実験手法SOLUTION NMR
主引用文献Conkunitzin-S1 is the first member of a new Kunitz-type neurotoxin family. Structural and functional characterization.
J. Biol. Chem., 280, 2005
1W8K
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Crystal structure of apical membrane antigen 1 from Plasmodium vivax
分子名称: APICAL MEMBRANE ANTIGEN 1, IMIDAZOLE
著者Pizarro, J.C, Vulliez-Le Normand, B, Chesne-Seck, M.-L, Kocken, C.H.M, Thomas, A.W, Bentley, G.A.
登録日2004-09-23
公開日2005-03-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of the Malaria Vaccine Candidate Apical Membrane Antigen 1
Science, 308, 2005
4FBM
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LipS and LipT, two metagenome-derived lipolytic enzymes increase the diversity of known lipase and esterase families
分子名称: BROMIDE ION, LipS lipolytic enzyme
著者Chow, J, Krauss, U, Dall Antonia, Y, Fersini, F, Schmeisser, C, Schmidt, M, Menyes, I, Bornscheuer, U, Lauinger, B, Bongen, P, Pietruszka, J, Eckstein, M, Thum, O, Liese, A, Mueller-Dieckmann, J, Jaeger, K.-E, Kovavic, F, Streit, W.R, Structural Proteomics in Europe (SPINE)
登録日2012-05-23
公開日2012-10-10
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The Metagenome-Derived Enzymes LipS and LipT Increase the Diversity of Known Lipases.
Plos One, 7, 2012
1W81
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Crystal structure of apical membrane antigen 1 from Plasmodium vivax
分子名称: APICAL MEMBRANE ANTIGEN 1, IMIDAZOLE
著者Pizarro, J.C, Vulliez-Le Normand, B, Chesne-Seck, M.-L, Kocken, C.H.M, Thomas, A.W, Bentley, G.A.
登録日2004-09-15
公開日2005-03-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Crystal Structure of the Malaria Vaccine Candidate Apical Membrane Antigen 1
Science, 308, 2005

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