8BGU

human MDM2-5S RNP

Summary for 8BGU

• Entry DOI: 10.2210/pdb8bgu/pdb
• EMDB information: 16036
• Descriptor: E3 ubiquitin-protein ligase Mdm2, 5S rRNA, 60S ribosomal protein L5, ... (5 entities in total)
• Functional Keywords: 5s rnp, mdm2, rna binding protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 149025.53

Authors

Castillo, N.,Thoms, M.,Flemming, D.,Hammaren, H.M.,Buschauer, R.,Ameismeier, M.,Bassler, J.,Beck, M.,Beckmann, R.,Hurt, E. (deposition date: 2022-10-28, release date: 2023-06-14, Last modification date: 2023-08-30)

• Primary citation: Castillo Duque de Estrada, N.M.,Thoms, M.,Flemming, D.,Hammaren, H.M.,Buschauer, R.,Ameismeier, M.,Bassler, J.,Beck, M.,Beckmann, R.,Hurt, E.; Structure of nascent 5S RNPs at the crossroad between ribosome assembly and MDM2-p53 pathways.; Nat.Struct.Mol.Biol., 30:1119-1131, 2023; PubMed: 37291423; DOI: 10.1038/s41594-023-01006-7

Experimental method

ELECTRON MICROSCOPY (4.1 Å)