2CA7

Conkunitzin-S1 Is The First Member Of A New Kunitz-Type Neurotoxin Family- Structural and Functional Characterization

Replaces:  1YL2

Summary for 2CA7

• Entry DOI: 10.2210/pdb2ca7/pdb
• NMR Information: BMRB: 6506
• Descriptor: CONKUNITZIN-S1 (1 entity in total)
• Functional Keywords: conkunitzin, neurotoxin, toxin, kunitz-type fold, potassium channel inhibitor, kunitz-domain
• Biological source: CONUS STRIATUS
• Total number of polymer chains: 1
• Total formula weight: 6944.69

Authors

Bayrhuber, M.,Vijayan, V.,Ferber, M.,Graf, R.,Korukottu, J.,Imperial, J.,Garrett, J.E.,Olivera, B.M.,Terlau, H.,Zweckstetter, M.,Becker, S. (deposition date: 2005-12-19, release date: 2006-01-05, Last modification date: 2020-01-15)

• Primary citation: Bayrhuber, M.,Vijayan, V.,Ferber, M.,Graf, R.,Korukottu, J.,Imperial, J.,Garrett, J.E.,Olivera, B.M.,Terlau, H.,Zweckstetter, M.,Becker, S.; Conkunitzin-S1 is the first member of a new Kunitz-type neurotoxin family. Structural and functional characterization.; J. Biol. Chem., 280:23766-23770, 2005; PubMed: 15833744; DOI: 10.1074/jbc.C500064200

Experimental method

SOLUTION NMR