6Y32

Structure of the GTPase heterodimer of human SRP54 and SRalpha

Summary for 6Y32

• Entry DOI: 10.2210/pdb6y32/pdb
• Related: 5L3Q
• Descriptor: Signal recognition particle 54 kDa protein, Signal recognition particle receptor subunit alpha, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... (6 entities in total)
• Functional Keywords: srp54 ng domain, sr alpha ng domain, targeting complex protein translocation, rna binding protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 8
• Total formula weight: 277703.15

Authors

Juaire, K.D.,Becker, M.M.M.,Wild, K.,Sinning, I. (deposition date: 2020-02-17, release date: 2020-09-23, Last modification date: 2024-01-24)

• Primary citation: Juaire, K.D.,Lapouge, K.,Becker, M.M.M.,Kotova, I.,Michelhans, M.,Carapito, R.,Wild, K.,Bahram, S.,Sinning, I.; Structural and Functional Impact of SRP54 Mutations Causing Severe Congenital Neutropenia.; Structure, 29:15-, 2021; PubMed: 33053321; DOI: 10.1016/j.str.2020.09.008

Experimental method

X-RAY DIFFRACTION (2.6 Å)