6Y32

Structure of the GTPase heterodimer of human SRP54 and SRalpha

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E, G (A, C, E, G)	Signal recognition particle 54 kDa protein	polymer	304	33511.7	4	UniProt (P61011) Pfam (PF02881) Pfam (PF00448)	Homo sapiens (Human)	SRP54
2	B, D, F, H (B, D, F, H)	Signal recognition particle receptor subunit alpha	polymer	315	34484.9	4	UniProt (P08240) Pfam (PF02881) Pfam (PF00448)	Homo sapiens (Human)	SR-alpha,Docking protein alpha,DP-alpha
3	CA, FA, I, K, P... (G, H, A, B, C...)	PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER	non-polymer		522.2	8	Chemie (GNP)
4	DA, GA, J, L, Q... (G, H, A, B, C...)	MAGNESIUM ION	non-polymer		24.3	8	Chemie (MG)
5	AA, BA, EA, HA, IA... (F, G, H, B, C...)	SULFATE ION	non-polymer		96.1	14	Chemie (SO4)
6	MA, NA, OA, PA, QA... (A, B, C, D, E...)	water	water		18.0	466	Chemie (HOH)

Sequence modifications

A, C, E, G: 1 - 296 (UniProt: P61011)

PDB	External Database	Details
Met -7	-	initiating methionine
Gly -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag

B, D, F, H: 332 - 638 (UniProt: P08240)

PDB	External Database	Details
Met 330	-	initiating methionine
Gly 331	-	expression tag
His 639	-	expression tag
His 640	-	expression tag
His 641	-	expression tag
His 642	-	expression tag
His 643	-	expression tag
His 644	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	271986.3
Non-Polymers*	Number of molecules	30
	Total formula weight	5716.9
All*	Total formula weight	277703.2

*Water molecules are not included.