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PDB: 40926 件

6XC9
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Immune receptor complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
著者Tran, T.M, Faridi, P, Lim, J.J, Ting, T.Y, Onwukwe, G, Bhattacharjee, P, Tresoldi, M.C.E, Cameron, J.F, La-Gruta, L.N, Purcell, W.A, Mannering, I.S, Rossjohn, J, Reid, H.H.
登録日2020-06-08
公開日2021-07-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献T cell receptor recognition of hybrid insulin peptides bound to HLA-DQ8.
Nat Commun, 12, 2021
4TYI
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Structural analysis of the human Fibroblast Growth Factor Receptor 4
分子名称: 4-amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]quinolin-2(1H)-one, Fibroblast growth factor receptor 4
著者Lesca, E, Lammens, A, Huber, R, Augustin, M.
登録日2014-07-08
公開日2014-09-24
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structural analysis of the human fibroblast growth factor receptor 4 kinase.
J.Mol.Biol., 426, 2014
4U5N
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IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR
分子名称: Importin subunit alpha-1, N~2~-[4-(pyridin-3-yl)benzyl]-L-lysyl-N-[(1R,2S,3R)-1-{[(2R)-1-amino-1-oxo-3-phenylpropan-2-yl]amino}-1,3-dihydroxybutan-2-yl]glycinamide
著者Stewart, M, Valkov, E, Holvey, R.S.
登録日2014-07-25
公開日2015-05-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design.
Chemmedchem, 10, 2015
4U5S
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IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR
分子名称: Importin subunit alpha-1, N-[(2S)-2-[(N~2~-acetyl-D-lysyl)amino]-3-(pyridin-3-ylmethoxy)propyl]-L-allothreonyl-D-phenylalaninamide
著者Stewart, M, Valkov, E, Holvey, R.S.
登録日2014-07-25
公開日2015-05-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design.
Chemmedchem, 10, 2015
5I3U
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STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE N-SITE COMPLEX; CATALYTIC INCORPORATION OF AZTMP to A DNA aptamer in CRYSTAL
分子名称: DNA (39-MER), GLYCEROL, HIV-1 REVERSE TRANSCRIPTASE P51 SUBUNIT, ...
著者Das, K, Arnold, E.
登録日2016-02-11
公開日2016-06-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Conformational States of HIV-1 Reverse Transcriptase for Nucleotide Incorporation vs Pyrophosphorolysis-Binding of Foscarnet.
Acs Chem.Biol., 11, 2016
6XCP
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Immune receptor complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Hybrid insulin peptide, ...
著者Tran, T.M, Faridi, P, Lim, J.J, Ting, T.Y, Onwukwe, G, Bhattacharjee, P, Jones, M.C, Tresoldi, E, Cameron, J.F, La-Gruta, L.N, Purcell, W.A, Mannering, I.S, Rossjohn, J, Reid, H.H.
登録日2020-06-08
公開日2021-07-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献T cell receptor recognition of hybrid insulin peptides bound to HLA-DQ8.
Nat Commun, 12, 2021
5I42
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Structure of HIV-1 Reverse Transcriptase in complex with a DNA aptamer, AZTTP, and CA(2+) ion
分子名称: 3'-AZIDO-3'-DEOXYTHYMIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (38-MER), ...
著者Das, K, Arnold, E.
登録日2016-02-11
公開日2016-06-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Conformational States of HIV-1 Reverse Transcriptase for Nucleotide Incorporation vs Pyrophosphorolysis-Binding of Foscarnet.
Acs Chem.Biol., 11, 2016
4UCU
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Fragment bound to H.influenza NAD dependent DNA ligase
分子名称: 1-(2,4-dimethylbenzyl)-6-oxo-1,6-dihydropyridine-3-carboxamide, 8-hydroxyquinoline-2-carboxylic acid, DNA LIGASE
著者Hale, M, Brassington, C, Carcanague, D, Embrey, K, Eyermann, C.J, Giacobbe, R.A, Gingipali, L, Gowravaram, M, Harang, J, Howard, T, Ioannidis, G, Jahic, H, Kutschke, A, Laganas, V.A, Loch, J, Miller, M.D, Murphy-Benenato, K.E, Oguto, H, Otterbein, L, Patel, S.J, Shapiro, A.B, Boriack-Sjodin, P.A.
登録日2014-12-04
公開日2015-10-14
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献From Fragments to Leads: Novel Bacterial Nad+-Dependent DNA Ligase Inhibitors
Tetrahedron Lett., 56, 2015
4U1O
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GluA2flip sLBD complexed with kainate and (R,R)-2b crystal form C
分子名称: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, Glutamate receptor 2, N,N'-[biphenyl-4,4'-diyldi(2R)propane-2,1-diyl]dipropane-2-sulfonamide
著者Chen, L, Gouaux, E.
登録日2014-07-15
公開日2014-08-20
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.8501 Å)
主引用文献Structure and Dynamics of AMPA Receptor GluA2 in Resting, Pre-Open, and Desensitized States.
Cell, 158, 2014
4U54
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IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR
分子名称: Importin subunit alpha-1, N-methyl-1-[3-(pyridin-3-yl)phenyl]methanamine
著者Stewart, M, Valkov, E, Holvey, R.S.
登録日2014-07-24
公開日2015-05-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design.
Chemmedchem, 10, 2015
4U7Y
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Structure of the complex of VPS4B MIT and IST1 MIM
分子名称: IST1 homolog, Vacuolar protein sorting-associated protein 4B
著者Guo, E.Z, Xu, Z.
登録日2014-07-31
公開日2015-02-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.502 Å)
主引用文献Distinct Mechanisms of Recognizing Endosomal Sorting Complex Required for Transport III (ESCRT-III) Protein IST1 by Different Microtubule Interacting and Trafficking (MIT) Domains.
J.Biol.Chem., 290, 2015
8T2P
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BU of 8t2p by Molmil
5TU-t1 - heterodimeric triplet polymerase ribozyme
分子名称: RNA (135-MER), RNA (152-MER)
著者McRae, E.K.S, Kristoffersen, E, Gallego, I, Hansen, K, Holliger, P, Andersen, E.S.
登録日2023-06-06
公開日2024-01-24
実験手法ELECTRON MICROSCOPY (5 Å)
主引用文献Cryo-EM structure and functional landscape of an RNA polymerase ribozyme.
Proc.Natl.Acad.Sci.USA, 121, 2024
4U2U
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Bak domain swapped dimer induced by BidBH3 with CHAPS
分子名称: Bcl-2 homologous antagonist/killer
著者Brouwer, J.M, Colman, P.M, Czabotar, P.E.
登録日2014-07-18
公開日2014-09-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Bak Core and Latch Domains Separate during Activation, and Freed Core Domains Form Symmetric Homodimers.
Mol.Cell, 55, 2014
8P0V
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BU of 8p0v by Molmil
Structure of the human Commander complex coiled coils, DENND10 and partial Retriever subcomplex
分子名称: Coiled-coil domain-containing protein 22, Coiled-coil domain-containing protein 93, DENN domain-containing protein 10, ...
著者Kumpula, E.P, Laulumaa, S, Huiskonen, J.T.
登録日2023-05-10
公開日2024-03-20
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (6.5 Å)
主引用文献Structure and interactions of the endogenous human Commander complex.
Nat.Struct.Mol.Biol., 31, 2024
4U5U
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IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR
分子名称: Importin subunit alpha-1, N~2~-[3-(pyridin-3-yl)benzyl]-L-lysinamide
著者Stewart, M, Valkov, E, Holvey, R.S.
登録日2014-07-25
公開日2015-05-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design.
Chemmedchem, 10, 2015
7NGU
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Mycobacterium tuberculosis transcriptional regulator EthR with bound inhibitory compound
分子名称: HTH-type transcriptional regulator EthR, SULFATE ION, ~{N}-(4-methoxyphenyl)-4-methyl-piperidine-1-carboxamide
著者Tomlinson, C.W.E, Tatum, N.J, Pohl, E.
登録日2021-02-09
公開日2022-02-23
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.26 Å)
主引用文献Systematic exploration of the hydrophobic capacity of the EthR binding site for lead compound optimization
To Be Published
4U58
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IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR
分子名称: Importin subunit alpha-1, N~2~-[4-(pyridin-3-yl)benzoyl]-L-lysinamide
著者Stewart, M, Valkov, E, Holvey, R.S.
登録日2014-07-24
公開日2015-05-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design.
Chemmedchem, 10, 2015
4U5O
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IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR
分子名称: Importin subunit alpha-1, N~2~-[4-(pyridin-3-yl)benzyl]-D-lysinamide
著者Stewart, M, Valkov, E, Holvey, R.S.
登録日2014-07-25
公開日2015-05-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design.
Chemmedchem, 10, 2015
7NGW
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BU of 7ngw by Molmil
Mycobacterium tuberculosis transcriptional regulator EthR with bound inhibitory compound
分子名称: HTH-type transcriptional regulator EthR, SULFATE ION, ~{N}-(4-hydroxyphenyl)-4-methyl-piperidine-1-carboxamide
著者Tomlinson, C.W.E, Tatum, N.J, Pohl, E.
登録日2021-02-09
公開日2022-02-23
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.26 Å)
主引用文献Systematic exploration of the hydrophobic capacity of the EthR binding site for lead compound optimization
To Be Published
7AJJ
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BU of 7ajj by Molmil
bovine ATP synthase dimer state3:state3
分子名称: 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ATP synthase F(0) complex subunit B1, mitochondrial, ...
著者Spikes, T.E, Montgomery, M.G, Walker, J.E.
登録日2020-09-29
公開日2021-02-03
最終更新日2021-02-24
実験手法ELECTRON MICROSCOPY (13.1 Å)
主引用文献Interface mobility between monomers in dimeric bovine ATP synthase participates in the ultrastructure of inner mitochondrial membranes.
Proc.Natl.Acad.Sci.USA, 118, 2021
7AJH
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BU of 7ajh by Molmil
bovine ATP synthase dimer state3:state1
分子名称: 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ATP synthase F(0) complex subunit B1, mitochondrial, ...
著者Spikes, T.E, Montgomery, M.G, Walker, J.E.
登録日2020-09-29
公開日2021-02-03
最終更新日2021-02-24
実験手法ELECTRON MICROSCOPY (9.7 Å)
主引用文献Interface mobility between monomers in dimeric bovine ATP synthase participates in the ultrastructure of inner mitochondrial membranes.
Proc.Natl.Acad.Sci.USA, 118, 2021
7AJD
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BU of 7ajd by Molmil
bovine ATP synthase dimer state1:state3
分子名称: 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ATP synthase F(0) complex subunit B1, mitochondrial, ...
著者Spikes, T.E, Montgomery, M.G, Walker, J.E.
登録日2020-09-29
公開日2021-02-03
最終更新日2021-02-24
実験手法ELECTRON MICROSCOPY (9 Å)
主引用文献Interface mobility between monomers in dimeric bovine ATP synthase participates in the ultrastructure of inner mitochondrial membranes.
Proc.Natl.Acad.Sci.USA, 118, 2021
7AJC
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BU of 7ajc by Molmil
bovine ATP synthase dimer state1:state2
分子名称: 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ATP synthase F(0) complex subunit B1, mitochondrial, ...
著者Spikes, T.E, Montgomery, M.G, Walker, J.E.
登録日2020-09-29
公開日2021-02-03
最終更新日2021-02-24
実験手法ELECTRON MICROSCOPY (11.9 Å)
主引用文献Interface mobility between monomers in dimeric bovine ATP synthase participates in the ultrastructure of inner mitochondrial membranes.
Proc.Natl.Acad.Sci.USA, 118, 2021
7AJG
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BU of 7ajg by Molmil
bovine ATP synthase dimer state2:state3
分子名称: 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ATP synthase F(0) complex subunit B1, mitochondrial, ...
著者Spikes, T.E, Montgomery, M.G, Walker, J.E.
登録日2020-09-29
公開日2021-02-03
最終更新日2021-02-24
実験手法ELECTRON MICROSCOPY (10.7 Å)
主引用文献Interface mobility between monomers in dimeric bovine ATP synthase participates in the ultrastructure of inner mitochondrial membranes.
Proc.Natl.Acad.Sci.USA, 118, 2021
4U7I
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BU of 4u7i by Molmil
Structure of the complex of Spartin MIT and IST1 MIM
分子名称: IST1 homolog, Spartin
著者Guo, E.Z, Xu, Z.
登録日2014-07-30
公開日2015-02-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.794 Å)
主引用文献Distinct Mechanisms of Recognizing Endosomal Sorting Complex Required for Transport III (ESCRT-III) Protein IST1 by Different Microtubule Interacting and Trafficking (MIT) Domains.
J.Biol.Chem., 290, 2015

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件を2024-09-04に公開中

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