5I42

Structure of HIV-1 Reverse Transcriptase in complex with a DNA aptamer, AZTTP, and CA(2+) ion

Summary for 5I42

Entry DOI	10.2210/pdb5i42/pdb
Related	5D3G 5HP1 5HRO 5I3U
Descriptor	HIV-1 REVERSE TRANSCRIPTASE P66 SUBUNIT, HIV-1 REVERSE TRANSCRIPTASE P51 SUBUNIT, DNA (38-MER), ... (5 entities in total)
Functional Keywords	rt, dna aptamer, azttp, polymerase, p site complex, 2-o-methylcytidine, transferase-dna complex, transferase/dna
Biological source	Human immunodeficiency virus type 1 group M subtype B (isolate BH10) (HIV-1) More
Total number of polymer chains	6
Total formula weight	256199.06
Authors	Das, K.,Arnold, E. (deposition date: 2016-02-11, release date: 2016-06-01, Last modification date: 2023-09-27)
Primary citation	Das, K.,Balzarini, J.,Miller, M.T.,Maguire, A.R.,DeStefano, J.J.,Arnold, E. Conformational States of HIV-1 Reverse Transcriptase for Nucleotide Incorporation vs Pyrophosphorolysis-Binding of Foscarnet. Acs Chem.Biol., 11:2158-2164, 2016 Cited by PubMed: 27192549 DOI: 10.1021/acschembio.6b00187 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.3 Å)

Structure validation