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4TYI

Structural analysis of the human Fibroblast Growth Factor Receptor 4

Summary for 4TYI
Entry DOI10.2210/pdb4tyi/pdb
Related4TYE 4TYG 4TYJ
DescriptorFibroblast growth factor receptor 4, 4-amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]quinolin-2(1H)-one (2 entities in total)
Functional Keywordsfibroblast growth factor receptor, kinase, transferase, dovitinib, ponatinb, proteros biostructures gmbh
Biological sourceHomo sapiens (Human)
Cellular locationCell membrane; Single-pass type I membrane protein. Isoform 2: Secreted. Isoform 3: Cytoplasm : P22455
Total number of polymer chains1
Total formula weight35081.49
Authors
Lesca, E.,Lammens, A.,Huber, R.,Augustin, M. (deposition date: 2014-07-08, release date: 2014-09-24, Last modification date: 2014-12-10)
Primary citationLesca, E.,Lammens, A.,Huber, R.,Augustin, M.
Structural analysis of the human fibroblast growth factor receptor 4 kinase.
J.Mol.Biol., 426:3744-3756, 2014
Cited by
PubMed: 25219510
DOI: 10.1016/j.jmb.2014.09.004
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.4 Å)
Structure validation

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