6UVO
| Structure of antibody 3G12 bound to the central conserved domain of RSV G | Descriptor: | 3G12 Fab Heavy chain, 3G12 Fab light chain, Major surface glycoprotein G | Authors: | Fedechkin, S.O, George, N.L, Nunez Castrejon, A.M, Dillen, J, Kauvar, L.M, DuBois, R.M. | Deposit date: | 2019-11-03 | Release date: | 2019-12-18 | Last modified: | 2024-10-30 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Conformational Flexibility in Respiratory Syncytial Virus G Neutralizing Epitopes. J.Virol., 94, 2020
|
|
7M0N
| The crystal structure of wild type PA endonuclease (A/Vietnam/1203/2004) in complex with Raltegravir | Descriptor: | GLYCEROL, MANGANESE (II) ION, N-(4-fluorobenzyl)-5-hydroxy-1-methyl-2-(1-methyl-1-{[(5-methyl-1,3,4-oxadiazol-2-yl)carbonyl]amino}ethyl)-6-oxo-1,6-di hydropyrimidine-4-carboxamide, ... | Authors: | Cuypers, M.G, Slavish, P.J, Yun, M.K, Dubois, R, Rankovic, Z, White, S.W. | Deposit date: | 2021-03-11 | Release date: | 2022-03-02 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Chemical scaffold recycling: Structure-guided conversion of an HIV integrase inhibitor into a potent influenza virus RNA-dependent RNA polymerase inhibitor designed to minimize resistance potential. Eur.J.Med.Chem., 247, 2023
|
|
5I30
| |
8CT6
| |
8UFN
| |
8UFO
| |
7UZT
| |
8SJ9
| Crystal structure of the H1 hemagglutinin COBRA X6 | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Dzimianski, J.V, DuBois, R.M. | Deposit date: | 2023-04-17 | Release date: | 2024-05-01 | Last modified: | 2024-10-30 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | Structural basis for the broad antigenicity of the computationally optimized influenza hemagglutinin X6. Structure, 32, 2024
|
|
7UYI
| |
5EWO
| Crystal structure of the human astrovirus 1 capsid protein spike domain at 0.95-A resolution | Descriptor: | SULFATE ION, Structural protein | Authors: | Bogdanoff, W, York, R.L, Yousefi, P.A, Haile, S, Tripathi, S, DuBois, R.M. | Deposit date: | 2015-11-20 | Release date: | 2015-12-23 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (0.95 Å) | Cite: | Structural, Mechanistic, and Antigenic Characterization of the Human Astrovirus Capsid. J.Virol., 90, 2015
|
|
5EWN
| Crystal structure of the human astrovirus 1 capsid protein core domain at 2.6 A resolution | Descriptor: | CHLORIDE ION, Structural protein | Authors: | York, R.L, Yousefi, P.A, Bogdanoff, W, Haile, S, Tripathi, S, DuBois, R.M. | Deposit date: | 2015-11-20 | Release date: | 2015-12-23 | Last modified: | 2024-11-13 | Method: | X-RAY DIFFRACTION (2.602 Å) | Cite: | Structural, Mechanistic, and Antigenic Characterization of the Human Astrovirus Capsid. J.Virol., 90, 2015
|
|
5KOV
| |
5KOU
| |
4B3V
| Crystal structure of the Rubella virus glycoprotein E1 in its post-fusion form crystallized in presence of 20mM of Calcium Acetate | Descriptor: | 2-acetamido-2-deoxy-beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... | Authors: | Vaney, M.C, DuBois, R.M, Tortorici, M.A, Rey, F.A. | Deposit date: | 2012-07-26 | Release date: | 2013-01-09 | Last modified: | 2024-10-23 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Functional and Evolutionary Insight from the Crystal Structure of Rubella Virus Protein E1. Nature, 493, 2013
|
|
5WNB
| Structure of antibody 3D3 bound to the linear epitope of RSV G | Descriptor: | ACETIC ACID, Major surface glycoprotein G, ZINC ION, ... | Authors: | Fedechkin, S.O, George, N.L, Wolff, J.T, Kauvar, L.M, DuBois, R.M. | Deposit date: | 2017-07-31 | Release date: | 2018-03-14 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structures of respiratory syncytial virus G antigen bound to broadly neutralizing antibodies. Sci Immunol, 3, 2018
|
|
5WNA
| Structure of antibody 3D3 bound to the central conserved region of RSV G | Descriptor: | Major surface glycoprotein G, mAb 3D3 Fab heavy chain, mAb 3D3 Fab light chain | Authors: | Fedechkin, S.O, George, N.L, Wolff, J.T, Kauvar, L.M, DuBois, R.M. | Deposit date: | 2017-07-31 | Release date: | 2018-03-14 | Last modified: | 2024-10-23 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structures of respiratory syncytial virus G antigen bound to broadly neutralizing antibodies. Sci Immunol, 3, 2018
|
|
5W1N
| |
5WN9
| Structure of antibody 2D10 bound to the central conserved region of RSV G | Descriptor: | Major surface glycoprotein G, scFv 2D10 | Authors: | Fedechkin, S.O, George, N.L, Wolff, J.T, Kauvar, L.M, DuBois, R.M. | Deposit date: | 2017-07-31 | Release date: | 2018-03-14 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (1.551 Å) | Cite: | Structures of respiratory syncytial virus G antigen bound to broadly neutralizing antibodies. Sci Immunol, 3, 2018
|
|
7RK1
| |
7RK2
| Crystal structure of the human astrovirus serotype 8 capsid spike in complex with scFv 2D9, an astrovirus-neutralizing antibody, at 2.65-A resolution | Descriptor: | Capsid protein VP25, scFv 2D9 | Authors: | Meyer, L, Cuellar, C, DuBois, R.M. | Deposit date: | 2021-07-21 | Release date: | 2021-10-13 | Last modified: | 2024-10-30 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Structures of Two Human Astrovirus Capsid/Neutralizing Antibody Complexes Reveal Distinct Epitopes and Inhibition of Virus Attachment to Cells. J.Virol., 96, 2022
|
|