5KOV

Crystal structure of the human astrovirus 2 capsid protein spike in complex with a single chain variable fragment of an astrovirus neutralizing antibody at 3.24-A resolution

Summary for 5KOV

Entry DOI	10.2210/pdb5kov/pdb
Descriptor	Capsid polyprotein VP90, PL-2 scFv chain, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
Functional Keywords	viral protein, capsid protein, icosahedral virus, single chain variable fragment.
Biological source	Human astrovirus-2 (HAstV-2) More
Total number of polymer chains	16
Total formula weight	422557.46
Authors	Bogdanoff, W.A.,DuBois, R.M. (deposition date: 2016-07-01, release date: 2016-11-09, Last modification date: 2023-10-04)
Primary citation	Bogdanoff, W.A.,Campos, J.,Perez, E.I.,Yin, L.,Alexander, D.L.,DuBois, R.M. Structure of a Human Astrovirus Capsid-Antibody Complex and Mechanistic Insights into Virus Neutralization. J. Virol., 91:-, 2017 Cited by PubMed: 27807234 DOI: 10.1128/JVI.01859-16 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.245 Å)

Structure validation