7ML8

The crystal structure of I38T mutant PA endonuclease (2009/H1N1/CALIFORNIA) in complex with SJ001023038

Summary for 7ML8

• Entry DOI: 10.2210/pdb7ml8/pdb
• Descriptor: Polymerase acidic protein, GLUTAMIC ACID, 5-hydroxy-N-[2-(4-hydroxy-3-methoxyphenyl)ethyl]-6-oxo-2-phenyl-1,6-dihydropyrimidine-4-carboxamide, ... (7 entities in total)
• Functional Keywords: nuclease, influenza, inhibitor resistance, viral protein, viral protein-inhibitor complex, viral protein/inhibitor
• Biological source: Influenza A virus (strain swl A/California/04/2009 H1N1); More
• Total number of polymer chains: 1
• Total formula weight: 24635.67

Authors

Cuypers, M.G.,Slavish, P.J.,Yun, M.K.,Dubois, R.,Rankovic, Z.,White, S.W. (deposition date: 2021-04-27, release date: 2021-10-27, Last modification date: 2023-10-18)

• Primary citation: Cuypers, M.G.,Slavish, P.J.,Yun, M.K.,Dubois, R.,Rankovic, Z.,White, S.W.; The crystal structure of I38T mutant PA endonuclease (2009/H1N1/CALIFORNIA) in complex with St Jude compound AC067-19; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.7 Å)