8CT6

1F8 mAb in complex with the computationally optimized broadly reactive H1 influenza hemagglutinin P1

Summary for 8CT6

• Entry DOI: 10.2210/pdb8ct6/pdb
• EMDB information: 26983
• Descriptor: COBRA P1 HA, 1F8 light chain, 1F8 heavy chain, ... (7 entities in total)
• Functional Keywords: hemagglutinin, influenza virus, cobra, monoclonal antibody, immune system, viral protein-immune system complex, viral protein/immune system
• Biological source: Influenza A virus; More
• Total number of polymer chains: 7
• Total formula weight: 290152.17

Authors

Dzimianski, J.V.,DuBois, R.M. (deposition date: 2022-05-13, release date: 2023-04-19, Last modification date: 2024-05-01)

• Primary citation: Dzimianski, J.V.,Han, J.,Sautto, G.A.,O'Rourke, S.M.,Cruz, J.M.,Pierce, S.R.,Ecker, J.W.,Carlock, M.A.,Nagashima, K.A.,Mousa, J.J.,Ross, T.M.,Ward, A.B.,DuBois, R.M.; Structural insights into the broad protection against H1 influenza viruses by a computationally optimized hemagglutinin vaccine.; Commun Biol, 6:454-454, 2023; PubMed: 37185989; DOI: 10.1038/s42003-023-04793-3

Experimental method

ELECTRON MICROSCOPY (3.1 Å)