7RK2

Crystal structure of the human astrovirus serotype 8 capsid spike in complex with scFv 2D9, an astrovirus-neutralizing antibody, at 2.65-A resolution

Summary for 7RK2

Entry DOI	10.2210/pdb7rk2/pdb
Descriptor	Capsid protein VP25, scFv 2D9 (3 entities in total)
Functional Keywords	viral protein, capsid protein, icosahedral virus, single chain variable fragment
Biological source	Human astrovirus-8 (HAstV-8) More
Total number of polymer chains	4
Total formula weight	104957.46
Authors	Meyer, L.,Cuellar, C.,DuBois, R.M. (deposition date: 2021-07-21, release date: 2021-10-13, Last modification date: 2023-10-18)
Primary citation	Ricemeyer, L.,Aguilar-Hernandez, N.,Lopez, T.,Espinosa, R.,Lanning, S.,Mukherjee, S.,Cuellar, C.,Lopez, S.,Arias, C.F.,DuBois, R.M. Structures of Two Human Astrovirus Capsid/Neutralizing Antibody Complexes Reveal Distinct Epitopes and Inhibition of Virus Attachment to Cells. J.Virol., 96:e0141521-e0141521, 2022 Cited by PubMed: 34613806 DOI: 10.1128/JVI.01415-21 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.65 Å)

Structure validation