7RK1
Crystal structure of the human astrovirus serotype 8 capsid spike in complex with scFv 3E8, an astrovirus-neutralizing antibody, at 2.05-A resolution
Summary for 7RK1
Entry DOI | 10.2210/pdb7rk1/pdb |
Descriptor | Capsid polyprotein VP70, scFv 3E8 (3 entities in total) |
Functional Keywords | viral protein, capsid protein, icosahedral virus, single chain variable fragment |
Biological source | Human astrovirus-8 (HAstV-8) More |
Total number of polymer chains | 4 |
Total formula weight | 105529.38 |
Authors | Meyer, L.,DuBois, R.M. (deposition date: 2021-07-21, release date: 2021-10-13, Last modification date: 2023-10-18) |
Primary citation | Ricemeyer, L.,Aguilar-Hernandez, N.,Lopez, T.,Espinosa, R.,Lanning, S.,Mukherjee, S.,Cuellar, C.,Lopez, S.,Arias, C.F.,DuBois, R.M. Structures of Two Human Astrovirus Capsid/Neutralizing Antibody Complexes Reveal Distinct Epitopes and Inhibition of Virus Attachment to Cells. J.Virol., 96:e0141521-e0141521, 2022 Cited by PubMed: 34613806DOI: 10.1128/JVI.01415-21 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
Download full validation report