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7RK1

Crystal structure of the human astrovirus serotype 8 capsid spike in complex with scFv 3E8, an astrovirus-neutralizing antibody, at 2.05-A resolution

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C
(A, B)
Capsid polyprotein VP70polymer23025886.12UniProt (Q9IFX1)
Pfam (PF12226)
Human astrovirus-8 (HAstV-8)
2B, D
(C, D)
scFv 3E8polymer24826878.62Mus musculus (mouse)
3E, F, G, H
(A, C, B, D)
waterwater18.0335Chemie (HOH)
Sequence modifications
A, B: 429 - 647 (UniProt: Q9IFX1)
PDBExternal DatabaseDetails
Met 427-initiating methionine
Gly 428-expression tag
Ala 648-expression tag
Ala 649-expression tag
Glu 650-expression tag
Leu 651-expression tag
Ala 652-expression tag
Leu 653-expression tag
Val 654-expression tag
Pro 655-expression tag
Arg 656-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight105529.4
All*Total formula weight105529.4
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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