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PDB: 346 results

4HK6
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Crystal structure of Cordyceps militaris IDCase in complex with 5-nitro-uracil
Descriptor: 5-nitrouracil, Uracil-5-carboxylate decarboxylase, ZINC ION
Authors:Xu, S, Zhu, J, Ding, J.
Deposit date:2012-10-15
Release date:2013-09-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.
Cell Res., 23, 2013
4HK7
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Crystal structure of Cordyceps militaris IDCase in complex with uracil
Descriptor: URACIL, Uracil-5-carboxylate decarboxylase, ZINC ION
Authors:Xu, S, Zhu, J, Ding, J.
Deposit date:2012-10-15
Release date:2013-09-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.189 Å)
Cite:Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.
Cell Res., 23, 2013
4HK5
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Crystal structure of Cordyceps militaris IDCase in apo form
Descriptor: Uracil-5-carboxylate decarboxylase, ZINC ION
Authors:Xu, S, Zhu, J, Ding, J.
Deposit date:2012-10-15
Release date:2013-09-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.
Cell Res., 23, 2013
4QXA
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Crystal structure of the Rab9A-RUTBC2 RBD complex
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Ras-related protein Rab-9A, ...
Authors:Zhang, Z, Wang, S, Ding, J.
Deposit date:2014-07-19
Release date:2014-09-10
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the Rab9A-RUTBC2 RBD complex reveals the molecular basis for the binding specificity of Rab9A with RUTBC2.
Structure, 22, 2014
1T0L
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BU of 1t0l by Molmil
Crystal structure of human cytosolic NADP(+)-dependent isocitrate dehydrogenase in complex with NADP, isocitrate, and calcium(2+)
Descriptor: CALCIUM ION, ISOCITRIC ACID, Isocitrate dehydrogenase [NADP] cytoplasmic, ...
Authors:Xu, X, Zhao, J, Peng, B, Huang, Q, Arnold, E, Ding, J.
Deposit date:2004-04-10
Release date:2004-06-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Structures of human cytosolic NADP-dependent isocitrate dehydrogenase reveal a novel self-regulatory mechanism of activity
J.Biol.Chem., 279, 2004
6JLQ
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BU of 6jlq by Molmil
Crystal structure of human USP46-WDR48-WDR20 complex
Descriptor: GLYCEROL, PHOSPHATE ION, Ubiquitin carboxyl-terminal hydrolase 46, ...
Authors:Zhu, H, Zhang, T, Ding, J.
Deposit date:2019-03-06
Release date:2019-07-10
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.101 Å)
Cite:Structural insights into the activation of USP46 by WDR48 and WDR20.
Cell Discov, 5, 2019
5C74
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Structure of a novel protein arginine methyltransferase
Descriptor: NICKEL (II) ION, Protein arginine N-methyltransferase SFM1, SULFATE ION
Authors:Lv, F, Ding, J.
Deposit date:2015-06-24
Release date:2016-01-13
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for Sfm1 functioning as a protein arginine methyltransferase.
Cell Discov, 1, 2015
8JKN
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BU of 8jkn by Molmil
T95R mutant IRF4 DNA-binding domain bound to an DNA containing GAAA motif
Descriptor: GAAA-Forward, GAAA-Reverse, Interferon regulatory factor 4
Authors:Wang, G, Feng, X, Ding, J.
Deposit date:2023-06-01
Release date:2023-09-20
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.92 Å)
Cite:Molecular basis for the functional roles of the multimorphic T95R mutation of IRF4 causing human autosomal dominant combined immunodeficiency.
Structure, 31, 2023
4RL2
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Structural and mechanistic insights into NDM-1 catalyzed hydrolysis of cephalosporins
Descriptor: (1R)-2-({(R)-carboxy[(2R,5S)-4-carboxy-5-methyl-5,6-dihydro-2H-1,3-thiazin-2-yl]methyl}amino)-2-oxo-1-phenylethanaminium, Beta-lactamase NDM-1, ZINC ION
Authors:Feng, H, Ding, J, Zhu, D, Liu, X, Xu, X, Zhang, Y, Zang, S, Wang, D.-C, Liu, W.
Deposit date:2014-10-15
Release date:2014-11-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.008 Å)
Cite:Structural and Mechanistic Insights into NDM-1 Catalyzed Hydrolysis of Cephalosporins.
J.Am.Chem.Soc., 136, 2014
4RM5
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Structural and mechanistic insights into NDM-1 catalyzed hydrolysis of cephalosporins
Descriptor: Beta-lactamase NDM-1, ZINC ION
Authors:Feng, H, Ding, J, Zhu, D, Liu, X, Xu, X, Zhang, Y, Zang, S, Wang, D.-C, Liu, W.
Deposit date:2014-10-19
Release date:2014-11-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and Mechanistic Insights into NDM-1 Catalyzed Hydrolysis of Cephalosporins.
J.Am.Chem.Soc., 136, 2014
7VKR
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Crystal structure of D. melanogaster SAMTOR in complex with SAM
Descriptor: CITRIC ACID, S-ADENOSYLMETHIONINE, S-adenosylmethionine sensor upstream of mTORC1
Authors:Tang, X, Zhang, T, Ding, J.
Deposit date:2021-09-30
Release date:2022-07-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Molecular mechanism of S -adenosylmethionine sensing by SAMTOR in mTORC1 signaling.
Sci Adv, 8, 2022
7VKQ
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Crystal structure of D. melanogaster SAMTOR in the SAH bound form
Descriptor: S-ADENOSYL-L-HOMOCYSTEINE, S-adenosylmethionine sensor upstream of mTORC1
Authors:Tang, X, Zhang, T, Ding, J.
Deposit date:2021-09-30
Release date:2022-07-20
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.094 Å)
Cite:Molecular mechanism of S -adenosylmethionine sensing by SAMTOR in mTORC1 signaling.
Sci Adv, 8, 2022
4RL0
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BU of 4rl0 by Molmil
Structural and mechanistic insights into NDM-1 catalyzed hydrolysis of cephalosporins
Descriptor: (2R,5S)-5-[(carbamoyloxy)methyl]-2-[(R)-carboxy{[(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetyl]amino}methyl]-5,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, Beta-lactamase NDM-1, ZINC ION
Authors:Feng, H, Ding, J, Zhu, D, Liu, X, Xu, X, Zhang, Y, Zang, S, Wang, D.-C, Liu, W.
Deposit date:2014-10-14
Release date:2014-11-19
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structural and Mechanistic Insights into NDM-1 Catalyzed Hydrolysis of Cephalosporins.
J.Am.Chem.Soc., 136, 2014
3OXL
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BU of 3oxl by Molmil
Human lysine methyltransferase Smyd3 in complex with AdoHcy (Form II)
Descriptor: S-ADENOSYL-L-HOMOCYSTEINE, SET and MYND domain-containing protein 3, ZINC ION
Authors:Xu, S, Wu, J, Sun, B, Zhong, C, Ding, J.
Deposit date:2010-09-21
Release date:2011-02-23
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structural and biochemical studies of human lysine methyltransferase Smyd3 reveal the important functional roles of its post-SET and TPR domains and the regulation of its activity by DNA binding
Nucleic Acids Res., 39, 2011
3DSF
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BU of 3dsf by Molmil
Crystal structure of anti-osteopontin antibody 23C3 in complex with W43A mutated epitope peptide
Descriptor: Fab fragment of anti-osteopontin antibody 23C3, Heavy chain, Light chain, ...
Authors:Du, J, Zhong, C, Yang, H, Ding, J.
Deposit date:2008-07-12
Release date:2008-10-14
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Molecular basis of recognition of human osteopontin by 23C3, a potential therapeutic antibody for treatment of rheumatoid arthritis
J.Mol.Biol., 382, 2008
4JLW
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BU of 4jlw by Molmil
Crystal structure of formaldehyde dehydrogenase from Pseudomonas aeruginosa
Descriptor: Glutathione-independent formaldehyde dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION, ...
Authors:Chen, S, Liao, Y.P, Wang, D.L, Wang, S, Ding, J.F, Wang, Y.M, Cai, L.J, Ran, X.Y, Zhu, H.X.
Deposit date:2013-03-13
Release date:2013-10-30
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of formaldehyde dehydrogenase from Pseudomonas aeruginosa: the binary complex with the cofactor NAD+.
Acta Crystallogr.,Sect.F, 69, 2013
3F6G
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BU of 3f6g by Molmil
Crystal structure of the regulatory domain of LiCMS in complexed with isoleucine - type II
Descriptor: Alpha-isopropylmalate synthase, ISOLEUCINE, SULFATE ION, ...
Authors:Zhang, P, Ma, J, Zhao, G, Ding, J.
Deposit date:2008-11-06
Release date:2009-04-21
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular basis of the inhibitor selectivity and insights into the feedback inhibition mechanism of citramalate synthase from Leptospira interrogans
Biochem.J., 421, 2009
3OXG
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human lysine methyltransferase Smyd3 in complex with AdoHcy (Form III)
Descriptor: S-ADENOSYL-L-HOMOCYSTEINE, SET and MYND domain-containing protein 3, ZINC ION
Authors:Xu, S, Wu, J, Sun, B, Zhong, C, Ding, J.
Deposit date:2010-09-21
Release date:2011-02-23
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.41 Å)
Cite:Structural and biochemical studies of human lysine methyltransferase Smyd3 reveal the important functional roles of its post-SET and TPR domains and the regulation of its activity by DNA binding.
Nucleic Acids Res., 39, 2011
3E9G
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BU of 3e9g by Molmil
Crystal structure long-form (residue1-124) of Eaf3 chromo domain
Descriptor: Chromatin modification-related protein EAF3
Authors:Sun, B, Hong, J, Zhang, P, Lin, D, Ding, J.
Deposit date:2008-08-22
Release date:2008-11-04
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Molecular Basis of the Interaction of Saccharomyces cerevisiae Eaf3 Chromo Domain with Methylated H3K36
J.Biol.Chem., 283, 2008
3VPV
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BU of 3vpv by Molmil
Crystal Structure of Pseudomonas aeruginosa Tsi2
Descriptor: Tse2 specific immunity protein 2
Authors:Wang, W, Ding, J, Wang, D.C.
Deposit date:2012-03-13
Release date:2012-03-28
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of Pseudomonas aeruginosa Tsi2
To be Published
2K3C
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BU of 2k3c by Molmil
Structural and Functional Characterization of TM IX of the NHE1 Isoform of the Na+/H+ Exchanger
Descriptor: TMIX peptide
Authors:Reddy, T, Ding, J, Li, X, Sykes, B.D, Fliegel, L, Rainey, J.K.
Deposit date:2008-05-01
Release date:2008-06-03
Last modified:2020-02-19
Method:SOLUTION NMR
Cite:Structural and Functional Characterization of Transmembrane Segment IX of the NHE1 Isoform of the Na+/H+ Exchanger.
J.Biol.Chem., 283, 2008
7D0P
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BU of 7d0p by Molmil
Crystal structure of human HBO1-BRPF2 in complex with propionyl-coenzyme A
Descriptor: BRD1 protein, CHLORIDE ION, Histone acetyltransferase KAT7, ...
Authors:Li, W, Ding, J.
Deposit date:2020-09-11
Release date:2021-07-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:HBO1 is a versatile histone acyltransferase critical for promoter histone acylations.
Nucleic Acids Res., 49, 2021
7D0Q
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Crystal structure of human HBO1-BRPF2 in complex with butyryl-coenzyme A
Descriptor: 1,2-ETHANEDIOL, BRD1 protein, Butyryl Coenzyme A, ...
Authors:Li, W, Ding, J.
Deposit date:2020-09-11
Release date:2021-07-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:HBO1 is a versatile histone acyltransferase critical for promoter histone acylations.
Nucleic Acids Res., 49, 2021
7D0O
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Crystal structure of human HBO1-BRPF2 in apo form
Descriptor: 1,2-ETHANEDIOL, BRD1 protein, Histone acetyltransferase KAT7, ...
Authors:Li, W, Ding, J.
Deposit date:2020-09-11
Release date:2021-07-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:HBO1 is a versatile histone acyltransferase critical for promoter histone acylations.
Nucleic Acids Res., 49, 2021
7D0S
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BU of 7d0s by Molmil
Crystal structure of human HBO1-BRPF2 in complex with succinyl-coenzyme A
Descriptor: BRD1 protein, Histone acetyltransferase KAT7, SUCCINYL-COENZYME A, ...
Authors:Li, W, Ding, J.
Deposit date:2020-09-11
Release date:2021-07-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:HBO1 is a versatile histone acyltransferase critical for promoter histone acylations.
Nucleic Acids Res., 49, 2021

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