3OXL
Human lysine methyltransferase Smyd3 in complex with AdoHcy (Form II)
Summary for 3OXL
Entry DOI | 10.2210/pdb3oxl/pdb |
Descriptor | SET and MYND domain-containing protein 3, ZINC ION, S-ADENOSYL-L-HOMOCYSTEINE (3 entities in total) |
Functional Keywords | smyd proteins, mynd, set domain, histone lysine methyltransferase, histone methylation, h3k4, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: Q9H7B4 |
Total number of polymer chains | 1 |
Total formula weight | 49758.76 |
Authors | |
Primary citation | Xu, S.,Wu, J.,Sun, B.,Zhong, C.,Ding, J. Structural and biochemical studies of human lysine methyltransferase Smyd3 reveal the important functional roles of its post-SET and TPR domains and the regulation of its activity by DNA binding Nucleic Acids Res., 39:4438-4449, 2011 Cited by PubMed: 21266482DOI: 10.1093/nar/gkr019 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.6 Å) |
Structure validation
Download full validation report