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PDB: 346 件
8GTK
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BU of 8gtk by Molmil
Crystal structure of IpaH7.8-LRR and GSDMB isoform-1 complex
分子名称: GSDMB isoform-1, Probable E3 ubiquitin-protein ligase ipaH7.8
著者Zhong, X, Hou, Y.J, Ding, J.
登録日2022-09-08
公開日2023-04-12
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural mechanisms for regulation of GSDMB pore-forming activity.
Nature, 616, 2023
8GTJ
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BU of 8gtj by Molmil
Crystal structure of IpaH7.8-LRR and GSDMB isoform-4 complex
分子名称: Isoform 4 of Gasdermin-B, Probable E3 ubiquitin-protein ligase ipaH7.8
著者Zhong, X, Hou, Y.J, Ding, J.
登録日2022-09-08
公開日2023-04-12
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural mechanisms for regulation of GSDMB pore-forming activity.
Nature, 616, 2023
3W8I
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BU of 3w8i by Molmil
Crystal structure of CCM3 in complex with the C-terminal regulatory domain of MST4
分子名称: Programmed cell death protein 10, Serine/threonine-protein kinase MST4
著者Xu, X, Wang, D.C, Ding, J.
登録日2013-03-13
公開日2013-07-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural Basis for the Unique Heterodimeric Assembly between Cerebral Cavernous Malformation 3 and Germinal Center Kinase III.
Structure, 21, 2013
1T03
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BU of 1t03 by Molmil
HIV-1 reverse transcriptase crosslinked to tenofovir terminated template-primer (complex P)
分子名称: MAGNESIUM ION, POL polyprotein, Synthetic oligonucleotide primer, ...
著者Tuske, S, Sarafianos, S.G, Ding, J, Arnold, E.
登録日2004-04-07
公開日2004-05-11
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structure of HIV-1 RT-DNA complexes before and after incorporation of the anti-AIDS drug tenofovir
Nat.Struct.Mol.Biol., 11, 2004
3QAH
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BU of 3qah by Molmil
Crystal structure of apo-form human MOF catalytic domain
分子名称: Probable histone acetyltransferase MYST1, ZINC ION
著者Sun, B, Tang, Q, Zhong, C, Ding, J.
登録日2011-01-11
公開日2011-07-06
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Regulation of the histone acetyltransferase activity of hMOF via autoacetylation of Lys274
Cell Res., 21, 2011
5GRF
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BU of 5grf by Molmil
Crystal structure of the alpha gamma mutant (gamma-K151A) of human IDH3 in complex with Mg(2+), citrate and ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, CITRIC ACID, Isocitrate dehydrogenase [NAD] subunit alpha, ...
著者Ma, T, Ding, J.
登録日2016-08-11
公開日2017-02-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Molecular mechanism of the allosteric regulation of the alpha gamma heterodimer of human NAD-dependent isocitrate dehydrogenase.
Sci Rep, 7, 2017
8GRU
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BU of 8gru by Molmil
Crystal structure of a constitutively active mutant of the alpha beta heterodimer of human IDH3 in complex with ICT, NAD and Ca
分子名称: CALCIUM ION, Human IDH3 alpha subunit, ISOCITRIC ACID, ...
著者Sun, P, Chen, X, Ding, J.
登録日2022-09-02
公開日2022-11-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.847 Å)
主引用文献Structures of a constitutively active mutant of human IDH3 reveal new insights into the mechanisms of allosteric activation and the catalytic reaction.
J.Biol.Chem., 298, 2022
5GRE
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BU of 5gre by Molmil
Crystal structure of the alpha gamma heterodimer of human IDH3 in complex with Mg(2+), citrate and ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, CITRIC ACID, Isocitrate dehydrogenase [NAD] subunit alpha, ...
著者Ma, T, Peng, Y, Ding, J.
登録日2016-08-11
公開日2017-02-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Molecular mechanism of the allosteric regulation of the alpha gamma heterodimer of human NAD-dependent isocitrate dehydrogenase.
Sci Rep, 7, 2017
4ZB3
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BU of 4zb3 by Molmil
Crystal structure of the apo AtNUDT7
分子名称: Nudix hydrolase 7, SULFATE ION
著者Tang, Q, Liu, C, Zhong, C, Ding, J.
登録日2015-04-14
公開日2015-09-09
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structures of Arabidopsis thaliana Nudix Hydrolase NUDT7 Reveal a Previously Unobserved Conformation.
Mol Plant, 8, 2015
5GRI
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BU of 5gri by Molmil
Crystal structure of the alpha gamma heterodimer of human IDH3 in complex with Mg(2+) and citrate
分子名称: CITRIC ACID, Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, ...
著者Ma, T, Peng, Y, Ding, J.
登録日2016-08-11
公開日2017-02-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Molecular mechanism of the allosteric regulation of the alpha gamma heterodimer of human NAD-dependent isocitrate dehydrogenase.
Sci Rep, 7, 2017
5GRL
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BU of 5grl by Molmil
Crystal structure of the alpha gamma heterodimer of human IDH3 in complex with Mg(2+), isocitrate and ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, ISOCITRIC ACID, Isocitrate dehydrogenase [NAD] subunit alpha, ...
著者Ma, T, Ding, J.
登録日2016-08-11
公開日2017-02-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献Molecular mechanism of the allosteric regulation of the alpha gamma heterodimer of human NAD-dependent isocitrate dehydrogenase.
Sci Rep, 7, 2017
3SP4
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BU of 3sp4 by Molmil
Crystal structure of aprataxin ortholog Hnt3 from Schizosaccharomyces pombe
分子名称: Aprataxin-like protein, SULFATE ION, ZINC ION
著者Gong, Y, Zhu, D, Ding, J, Dou, C, Ren, X, Jiang, T, Wang, D.
登録日2011-07-01
公開日2011-10-12
最終更新日2013-07-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structures of aprataxin ortholog Hnt3 reveal the mechanism for reversal of 5'-adenylated DNA
Nat.Struct.Mol.Biol., 18, 2011
3EO9
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BU of 3eo9 by Molmil
Crystal structure the Fab fragment of Efalizumab
分子名称: Efalizumab Fab fragment, heavy chain, light chain
著者Li, S, Ding, J.
登録日2008-09-26
公開日2009-04-14
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Efalizumab binding to the LFA-1 alphaL I domain blocks ICAM-1 binding via steric hindrance.
Proc.Natl.Acad.Sci.USA, 106, 2009
6L57
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BU of 6l57 by Molmil
Crystal structure of the alpha gamma heterodimer of human IDH3 in complex with CIT , Mg and ATP binding at allosteric site.
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CITRIC ACID, Isocitrate dehydrogenase [NAD] subunit alpha, ...
著者Sun, P, Ding, J.
登録日2019-10-22
公開日2020-04-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.302 Å)
主引用文献Molecular mechanism of the dual regulatory roles of ATP on the alpha gamma heterodimer of human NAD-dependent isocitrate dehydrogenase.
Sci Rep, 10, 2020
6L59
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BU of 6l59 by Molmil
Crystal structure of the alpha gamma heterodimer of human IDH3 in complex with CIT, Mg and ATP binding at allosteric site and Mg, ATP binding at active site.
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CITRIC ACID, Isocitrate dehydrogenase [NAD] subunit alpha, ...
著者Sun, P, Ding, J.
登録日2019-10-22
公開日2020-04-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.254 Å)
主引用文献Molecular mechanism of the dual regulatory roles of ATP on the alpha gamma heterodimer of human NAD-dependent isocitrate dehydrogenase.
Sci Rep, 10, 2020
1TVR
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BU of 1tvr by Molmil
HIV-1 RT/9-CL TIBO
分子名称: 4-CHLORO-8-METHYL-7-(3-METHYL-BUT-2-ENYL)-6,7,8,9-TETRAHYDRO-2H-2,7,9A-TRIAZA-BENZO[CD]AZULENE-1-THIONE, REVERSE TRANSCRIPTASE
著者Das, K, Ding, J, Hsiou, Y, Arnold, E.
登録日1996-04-16
公開日1997-03-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structures of 8-Cl and 9-Cl TIBO complexed with wild-type HIV-1 RT and 8-Cl TIBO complexed with the Tyr181Cys HIV-1 RT drug-resistant mutant.
J.Mol.Biol., 264, 1996
1L3K
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BU of 1l3k by Molmil
UP1, THE TWO RNA-RECOGNITION MOTIF DOMAIN OF HNRNP A1
分子名称: HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A1
著者Vitali, J, Ding, J, Jiang, J, Zhang, Y, Krainer, A.R, Xu, R.-M.
登録日2002-02-27
公開日2002-04-17
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Correlated alternative side chain conformations in the RNA-recognition motif of heterogeneous nuclear ribonucleoprotein A1.
Nucleic Acids Res., 30, 2002
8GS5
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BU of 8gs5 by Molmil
Crystal structure of a constitutively active mutant of human IDH3 holoenzyme in apo form
分子名称: Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, Isocitrate dehydrogenase [NAD] subunit gamma, ...
著者Sun, P, Chen, X, Ding, J.
登録日2022-09-04
公開日2022-11-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (4.486 Å)
主引用文献Structures of a constitutively active mutant of human IDH3 reveal new insights into the mechanisms of allosteric activation and the catalytic reaction.
J.Biol.Chem., 298, 2022
8GRB
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BU of 8grb by Molmil
Crystal structure of a constitutively active mutant of the alpha beta heterodimer of human IDH3
分子名称: Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, Isoform A of Isocitrate dehydrogenase [NAD] subunit beta
著者Sun, P, Chen, X, Ding, J.
登録日2022-09-01
公開日2022-12-07
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.848 Å)
主引用文献Structures of a constitutively active mutant of human IDH3 reveal new insights into the mechanisms of allosteric activation and the catalytic reaction.
J.Biol.Chem., 298, 2022
6V97
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BU of 6v97 by Molmil
Kindlin-3 double deletion mutant short form
分子名称: Fermitin family homolog 3
著者Xu, Z, Zhang, T.L, Xu, Z, Sun, J.J, Ding, J.P, Ma, Y.Q.
登録日2019-12-13
公開日2020-07-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.381 Å)
主引用文献Structure basis of the FERM domain of kindlin-3 in supporting integrin alpha IIb beta 3 activation in platelets.
Blood Adv, 4, 2020
6V9G
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BU of 6v9g by Molmil
Kindlin-3 double deletion mutant long form
分子名称: Fermitin family homolog 3
著者Xu, Z, Zhang, T.L, Xu, Z, Sun, J.J, Ding, J.P, Ma, Y.Q.
登録日2019-12-13
公開日2020-07-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structure basis of the FERM domain of kindlin-3 in supporting integrin alpha IIb beta 3 activation in platelets.
Blood Adv, 4, 2020
8GTN
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BU of 8gtn by Molmil
Cryo-EM structure of the gasdermin B pore
分子名称: Isoform 4 of Gasdermin-B
著者Hou, Y.J, Cheng, H, Ding, J.
登録日2022-09-08
公開日2023-04-12
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.17 Å)
主引用文献Structural mechanisms for regulation of GSDMB pore-forming activity.
Nature, 616, 2023
1UWB
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BU of 1uwb by Molmil
TYR 181 CYS HIV-1 RT/8-CL TIBO
分子名称: 5-CHLORO-8-METHYL-7-(3-METHYL-BUT-2-ENYL)-6,7,8,9-TETRAHYDRO-2H-2,7,9A-TRIAZA-BENZO[CD]AZULENE-1-THIONE, REVERSE TRANSCRIPTASE
著者Das, K, Ding, J, Hsiou, Y, Arnold, E.
登録日1996-11-21
公開日1997-05-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structures of 8-Cl and 9-Cl TIBO complexed with wild-type HIV-1 RT and 8-Cl TIBO complexed with the Tyr181Cys HIV-1 RT drug-resistant mutant.
J.Mol.Biol., 264, 1996
8W75
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BU of 8w75 by Molmil
Structure of Drosophila melanogaster L-2-hydroxyglutarate dehydrogenase
分子名称: DODECYL-BETA-D-MALTOSIDE, FI05204p, FLAVIN-ADENINE DINUCLEOTIDE
著者Yang, J, Chen, X, Jin, S, Ding, J.
登録日2023-08-30
公開日2023-11-29
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structure and biochemical characterization of l-2-hydroxyglutarate dehydrogenase and its role in the pathogenesis of l-2-hydroxyglutaric aciduria.
J.Biol.Chem., 300, 2023
8W7F
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BU of 8w7f by Molmil
Structure of Drosophila melanogaster L-2-hydroxyglutarate dehydrogenase bound with FAD and a sulfate ion
分子名称: DODECYL-BETA-D-MALTOSIDE, FI05204p, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Yang, J, Chen, X, Jin, S, Ding, J.
登録日2023-08-30
公開日2023-11-29
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.299 Å)
主引用文献Structure and biochemical characterization of l-2-hydroxyglutarate dehydrogenase and its role in the pathogenesis of l-2-hydroxyglutaric aciduria.
J.Biol.Chem., 300, 2023

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