8JYZ
 
 | | Cryo-EM structure of RCD-1 pore from Neurospora crassa | | 分子名称: | Gasdermin-like protein rcd-1-1, Gasdermin-like protein rcd-1-2 | | 著者 | Hou, Y.J, Sun, Q, Li, Y, Ding, J. | | 登録日 | 2023-07-04 | | 公開日 | 2024-05-01 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.63 Å) | | 主引用文献 | Cleavage-independent activation of ancient eukaryotic gasdermins and structural mechanisms.
Science, 384, 2024
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2H08
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4RL0
 | | Structural and mechanistic insights into NDM-1 catalyzed hydrolysis of cephalosporins | | 分子名称: | (2R,5S)-5-[(carbamoyloxy)methyl]-2-[(R)-carboxy{[(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetyl]amino}methyl]-5,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, Beta-lactamase NDM-1, ZINC ION | | 著者 | Feng, H, Ding, J, Zhu, D, Liu, X, Xu, X, Zhang, Y, Zang, S, Wang, D.-C, Liu, W. | | 登録日 | 2014-10-14 | | 公開日 | 2014-11-19 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Structural and Mechanistic Insights into NDM-1 Catalyzed Hydrolysis of Cephalosporins.
J.Am.Chem.Soc., 136, 2014
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3F6H
 | | Crystal structure of the regulatory domain of LiCMS in complexed with isoleucine - type III | | 分子名称: | Alpha-isopropylmalate synthase, ISOLEUCINE, ZINC ION | | 著者 | Zhang, P, Ma, J, Zhao, G, Ding, J. | | 登録日 | 2008-11-06 | | 公開日 | 2009-04-21 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Molecular basis of the inhibitor selectivity and insights into the feedback inhibition mechanism of citramalate synthase from Leptospira interrogans
Biochem.J., 421, 2009
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6LPX
 | | Crystal structure of human D-2-hydroxyglutarate dehydrogenase in complex with 2-oxoglutarate (2-OG) | | 分子名称: | 2-OXOGLUTARIC ACID, D-2-hydroxyglutarate dehydrogenase, mitochondrial, ... | | 著者 | Yang, J, Zhu, H, Ding, J. | | 登録日 | 2020-01-12 | | 公開日 | 2021-01-13 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure, substrate specificity, and catalytic mechanism of human D-2-HGDH and insights into pathogenicity of disease-associated mutations.
Cell Discov, 7, 2021
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3E9F
 | | Crystal structure short-form (residue1-113) of Eaf3 chromo domain | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Chromatin modification-related protein EAF3 | | 著者 | Sun, B, Hong, J, Zhang, P, Lin, D, Ding, J. | | 登録日 | 2008-08-22 | | 公開日 | 2008-11-04 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Molecular Basis of the Interaction of Saccharomyces cerevisiae Eaf3 Chromo Domain with Methylated H3K36
J.Biol.Chem., 283, 2008
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4HJW
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3CXD
 | | Crystal structure of anti-osteopontin antibody 23C3 in complex with its epitope peptide | | 分子名称: | Fab fragment of anti-osteopontin antibody 23C3, Heavy chain, Light chain, ... | | 著者 | Du, J, Yang, H, Zhong, C, Ding, J. | | 登録日 | 2008-04-24 | | 公開日 | 2008-10-14 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Molecular basis of recognition of human osteopontin by 23C3, a potential therapeutic antibody for treatment of rheumatoid arthritis
J.Mol.Biol., 382, 2008
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6KE3
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6KDF
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8HVI
 | | Activation mechanism of GPR132 by compound NOX-6-7 | | 分子名称: | 3-methyl-5-[(4-oxidanylidene-4-phenyl-butanoyl)amino]-1-benzofuran-2-carboxylic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Wang, J.L, Ding, J.H, Sun, J.P, Yu, X. | | 登録日 | 2022-12-26 | | 公開日 | 2023-10-11 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (3.04 Å) | | 主引用文献 | Functional screening and rational design of compounds targeting GPR132 to treat diabetes.
Nat Metab, 5, 2023
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4HK7
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4HK5
 | | Crystal structure of Cordyceps militaris IDCase in apo form | | 分子名称: | Uracil-5-carboxylate decarboxylase, ZINC ION | | 著者 | Xu, S, Zhu, J, Ding, J. | | 登録日 | 2012-10-15 | | 公開日 | 2013-09-11 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.
Cell Res., 23, 2013
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5XYN
 | | The crystal structure of Csm2-Psy3-Shu1-Shu2 complex from budding yeast | | 分子名称: | Chromosome segregation in meiosis protein 2, Platinum sensitivity protein 3, Suppressor of HU sensitivity involved in recombination protein 1, ... | | 著者 | Zhang, S, Zhang, T, Ding, J. | | 登録日 | 2017-07-09 | | 公開日 | 2017-11-08 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structural basis for the functional role of the Shu complex in homologous recombination.
Nucleic Acids Res., 45, 2017
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7CY7
 | | Crystal Structure of CMD1 in complex with DNA | | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(P*CP*GP*CP*GP*CP*GP*GP*GP*A)-3'), FE (II) ION, ... | | 著者 | Li, W, Zhang, T, Sun, M, Ding, J. | | 登録日 | 2020-09-03 | | 公開日 | 2020-12-30 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Molecular mechanism for vitamin C-derived C 5 -glyceryl-methylcytosine DNA modification catalyzed by algal TET homologue CMD1.
Nat Commun, 12, 2021
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7CY6
 | | Crystal Structure of CMD1 in complex with 5mC-DNA | | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(P*(5CM)P*GP*CP*GP*CP*GP*GP*GP*A)-3'), FE (II) ION, ... | | 著者 | Li, W, Zhang, T, Sun, M, Ding, J. | | 登録日 | 2020-09-03 | | 公開日 | 2020-12-30 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Molecular mechanism for vitamin C-derived C 5 -glyceryl-methylcytosine DNA modification catalyzed by algal TET homologue CMD1.
Nat Commun, 12, 2021
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7CY8
 | | Crystal Structure of CMD1 in complex with 5mC-DNA and vitamin C | | 分子名称: | 1,2-ETHANEDIOL, ASCORBIC ACID, DNA (5'-D(P*(5CM)P*GP*CP*GP*CP*GP*GP*GP*A)-3'), ... | | 著者 | Li, W, Zhang, T, Sun, M, Ding, J. | | 登録日 | 2020-09-03 | | 公開日 | 2020-12-30 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Molecular mechanism for vitamin C-derived C 5 -glyceryl-methylcytosine DNA modification catalyzed by algal TET homologue CMD1.
Nat Commun, 12, 2021
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7WR3
 | | Crystal structure of MBP-fused OspC3 in complex with calmodulin | | 分子名称: | Calmodulin-1, MBP-fused OspC3, NICOTINAMIDE, ... | | 著者 | Hou, Y.J, Zeng, H, Shao, F, Ding, J. | | 登録日 | 2022-01-26 | | 公開日 | 2023-01-25 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | | 主引用文献 | Structural mechanisms of calmodulin activation of Shigella effector OspC3 to ADP-riboxanate caspase-4/11 and block pyroptosis.
Nat.Struct.Mol.Biol., 30, 2023
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5Y7L
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2HCR
 | | crystal structure of human phosphoribosyl pyrophosphate synthetase 1 in complex with AMP(ATP), cadmium and sulfate ion | | 分子名称: | ADENOSINE MONOPHOSPHATE, CADMIUM ION, Ribose-phosphate pyrophosphokinase I, ... | | 著者 | Li, S, Peng, B, Ding, J. | | 登録日 | 2006-06-18 | | 公開日 | 2006-10-24 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of human phosphoribosylpyrophosphate synthetase 1 reveals a novel allosteric site
Biochem.J., 401, 2007
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2QFY
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4HK6
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4JLW
 | | Crystal structure of formaldehyde dehydrogenase from Pseudomonas aeruginosa | | 分子名称: | Glutathione-independent formaldehyde dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION, ... | | 著者 | Chen, S, Liao, Y.P, Wang, D.L, Wang, S, Ding, J.F, Wang, Y.M, Cai, L.J, Ran, X.Y, Zhu, H.X. | | 登録日 | 2013-03-13 | | 公開日 | 2013-10-30 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structure of formaldehyde dehydrogenase from Pseudomonas aeruginosa: the binary complex with the cofactor NAD+.
Acta Crystallogr.,Sect.F, 69, 2013
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7BTC
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5YVT
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