7QYR
 
 | | Crystal structure of RimK from Pseudomonas aeruginosa PAO1 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Probable alpha-L-glutamate ligase, poly-glutamate | | 著者 | Thompson, C.M.A, Little, R.H, Stevenson, C.E.M, Lawson, D.M, Malone, J.G. | | 登録日 | 2022-01-29 | | 公開日 | 2022-10-05 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural insights into the mechanism of adaptive ribosomal modification by Pseudomonas RimK.
Proteins, 91, 2023
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7QYS
 | | Crystal structure of RimK from Pseudomonas syringae DC3000 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Probable alpha-L-glutamate ligase | | 著者 | Thompson, C.M.A, Little, R.H, Stevenson, C.E.M, Lawson, D.M, Malone, J.G. | | 登録日 | 2022-01-29 | | 公開日 | 2022-10-05 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural insights into the mechanism of adaptive ribosomal modification by Pseudomonas RimK.
Proteins, 91, 2023
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3OUV
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3OYO
 | | Crystal structure of hemopexin fold protein CP4 from cow pea | | 分子名称: | CALCIUM ION, CHLORIDE ION, SODIUM ION, ... | | 著者 | Gaur, V, Chanana, V, Salunke, D.M. | | 登録日 | 2010-09-23 | | 公開日 | 2011-02-09 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The structure of a haemopexin-fold protein from cow pea (Vigna unguiculata) suggests functional diversity of haemopexins in plants
Acta Crystallogr.,Sect.F, 67, 2011
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3PSC
 | | Bovine GRK2 in complex with Gbetagamma subunits | | 分子名称: | Beta-adrenergic receptor kinase 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | | 著者 | Thal, D.M, Tesmer, J.J. | | 登録日 | 2010-12-01 | | 公開日 | 2011-06-01 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.67 Å) | | 主引用文献 | Molecular Mechanism of Selectivity among G Protein-Coupled Receptor Kinase 2 Inhibitors.
Mol.Pharmacol., 80, 2011
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3PRV
 | | Nucleoside diphosphate kinase B from Trypanosoma cruzi | | 分子名称: | Nucleoside diphosphate kinase | | 著者 | Souza, T.A.C.B, Trindade, D.M, Tonoli, C.C.C, Santos, C.R, Oliveira, A.H.C, Murakami, M.T. | | 登録日 | 2010-11-30 | | 公開日 | 2011-05-18 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | | 主引用文献 | Molecular adaptability of nucleoside diphosphate kinase b from trypanosomatid parasites: stability, oligomerization and structural determinants of nucleotide binding.
Mol Biosyst, 7, 2011
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3PND
 | | FAD binding by ApbE protein from Salmonella enterica: a new class of FAD binding proteins | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, Thiamine biosynthesis lipoprotein ApbE | | 著者 | Boyd, J.M, Endrizzi, J.A, Hamilton, T.L, Christopherson, M.R, Mulder, D.W, Downs, D.M, Peters, J.W. | | 登録日 | 2010-11-18 | | 公開日 | 2011-01-05 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | FAD binding by ApbE protein from Salmonella enterica: a new class of FAD-binding proteins.
J.Bacteriol., 193, 2011
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3PVU
 | | Bovine GRK2 in complex with Gbetagamma subunits and a selective kinase inhibitor (CMPD101) | | 分子名称: | 3-({[4-methyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]methyl}amino)-N-[2-(trifluoromethyl)benzyl]benzamide, Beta-adrenergic receptor kinase 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Thal, D.M, Tesmer, J.J. | | 登録日 | 2010-12-07 | | 公開日 | 2011-06-01 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | Molecular Mechanism of Selectivity among G Protein-Coupled Receptor Kinase 2 Inhibitors.
Mol.Pharmacol., 80, 2011
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3PWY
 | | Crystal structure of an extender (SPD28345)-modified human PDK1 complex 2 | | 分子名称: | 3-phosphoinositide-dependent protein kinase 1, N-[2-({6-[(2-sulfanylethyl)amino]pyrimidin-4-yl}amino)ethyl]propanamide | | 著者 | Elling, R.A, Penny, D.M, Simmons, R.L, Erlanson, D.A, Romanowski, M.J. | | 登録日 | 2010-12-09 | | 公開日 | 2011-04-20 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Discovery of a potent and highly selective PDK1 inhibitor via fragment-based drug discovery.
Bioorg.Med.Chem.Lett., 21, 2011
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3PE1
 | | Crystal structure of human protein kinase CK2 alpha subunit in complex with the inhibitor CX-4945 | | 分子名称: | 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid, Casein kinase II subunit alpha, SULFATE ION | | 著者 | Battistutta, R, Papinutto, E, Lolli, G, Pierre, F, Haddach, M, Ryckman, D.M. | | 登録日 | 2010-10-25 | | 公開日 | 2011-09-07 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Unprecedented selectivity and structural determinants of a new class of protein kinase CK2 inhibitors in clinical trials for the treatment of cancer.
Biochemistry, 50, 2011
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3PDS
 | | Irreversible Agonist-Beta2 Adrenoceptor Complex | | 分子名称: | 8-hydroxy-5-[(1R)-1-hydroxy-2-({2-[3-methoxy-4-(3-sulfanylpropoxy)phenyl]ethyl}amino)ethyl]quinolin-2(1H)-one, CHOLESTEROL, Fusion protein Beta-2 adrenergic receptor/Lysozyme, ... | | 著者 | Rosenbaum, D.M, Zhang, C, Lyons, J.A, Holl, R, Aragao, D, Arlow, D.H, Rasmussen, S.G.F, Choi, H.-J, DeVree, B.T, Sunahara, R.K, Chae, P.S, Gellman, S.H, Dror, R.O, Shaw, D.E, Weis, W.I, Caffrey, M, Gmeiner, P, Kobilka, B.K. | | 登録日 | 2010-10-24 | | 公開日 | 2011-01-12 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Structure and function of an irreversible agonist-beta(2) adrenoceptor complex
Nature, 469, 2011
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3PE2
 | | Crystal structure of human protein kinase CK2 in complex with the inhibitor CX-5011 | | 分子名称: | 5-[(3-ethynylphenyl)amino]pyrimido[4,5-c]quinoline-8-carboxylic acid, Casein kinase II subunit alpha, SULFATE ION | | 著者 | Battistutta, R, Papinutto, E, Lolli, G, Pierre, F, Haddach, M, Ryckman, D.M. | | 登録日 | 2010-10-25 | | 公開日 | 2011-09-07 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Unprecedented selectivity and structural determinants of a new class of protein kinase CK2 inhibitors in clinical trials for the treatment of cancer.
Biochemistry, 50, 2011
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3R1H
 | | Crystal structure of the Class I ligase ribozyme-substrate preligation complex, C47U mutant, Ca2+ bound | | 分子名称: | 5'-R(*UP*CP*CP*AP*GP*UP*A)-3', CALCIUM ION, Class I ligase ribozyme, ... | | 著者 | Shechner, D.M, Bartel, D.P. | | 登録日 | 2011-03-10 | | 公開日 | 2011-08-31 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | | 主引用文献 | The structural basis of RNA-catalyzed RNA polymerization.
Nat.Struct.Mol.Biol., 18, 2011
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3QUZ
 | | Structure of the mouse CD1d-NU-alpha-GalCer-iNKT TCR complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ... | | 著者 | Li, Y, Girardi, E, Yu, E.D, Zajonc, D.M. | | 登録日 | 2011-02-24 | | 公開日 | 2011-06-29 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Galactose-modified iNKT cell agonists stabilized by an induced fit of CD1d prevent tumour metastasis.
Embo J., 30, 2011
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3QUY
 | | Structure of the mouse CD1d-BnNH-GSL-1'-iNKT TCR complex | | 分子名称: | (2S,3R,4S,5R,6S)-6-[(2S,3S,4R)-2-(hexacosanoylamino)-3,4-dihydroxy-octadecoxy]-3,4,5-trihydroxy-N-(phenylmethyl)oxane-2-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Li, Y, Girardi, E, Yu, E.D, Zajonc, D.M. | | 登録日 | 2011-02-24 | | 公開日 | 2011-06-29 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Galactose-modified iNKT cell agonists stabilized by an induced fit of CD1d prevent tumour metastasis.
Embo J., 30, 2011
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3O78
 | | The structure of Ca2+ Sensor (Case-12) | | 分子名称: | CALCIUM ION, Myosin light chain kinase, smooth muscle,Green fluorescent protein,Green fluorescent protein,Calmodulin-1 | | 著者 | Leder, L, Stark, W, Freuler, F, Marsh, M, Meyerhofer, M, Stettler, T, Mayr, L.M, Britanova, O.V, Strukova, L.A, Chudakov, D.M. | | 登録日 | 2010-07-30 | | 公開日 | 2010-09-29 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | The structure of Ca2+ sensor Case16 reveals the mechanism of reaction to low Ca2+ concentrations
Sensors (Basel), 10, 2010
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7SR8
 | | Molecular mechanism of the the wake-promoting agent TAK-925 | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Hypocretin receptor type 2, ... | | 著者 | Yin, J, Chapman, K, Lian, P, De Brabander, J.K, Rosenbaum, D.M. | | 登録日 | 2021-11-08 | | 公開日 | 2022-06-08 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Molecular mechanism of the wake-promoting agent TAK-925.
Nat Commun, 13, 2022
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3QUX
 | | Structure of the mouse CD1d-alpha-C-GalCer-iNKT TCR complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ... | | 著者 | Li, Y, Girardi, E, Yu, E.D, Zajonc, D.M. | | 登録日 | 2011-02-24 | | 公開日 | 2011-06-29 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | | 主引用文献 | Galactose-modified iNKT cell agonists stabilized by an induced fit of CD1d prevent tumour metastasis.
Embo J., 30, 2011
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3OJD
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3OR7
 | | On the structural basis of modal gating behavior in K+channels - E71I | | 分子名称: | POTASSIUM ION, Voltage-gated potassium channel, antibody fab fragment heavy chain, ... | | 著者 | Chakrapani, S, Cordero-Morales, J.F, Jogini, V, Pan, A.C, Cortes, D.M, Roux, B, Perozo, E. | | 登録日 | 2010-09-06 | | 公開日 | 2011-01-05 | | 最終更新日 | 2018-08-29 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | On the structural basis of modal gating behavior in K(+) channels.
Nat.Struct.Mol.Biol., 18, 2011
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3P0G
 | | Structure of a nanobody-stabilized active state of the beta2 adrenoceptor | | 分子名称: | 8-[(1R)-2-{[1,1-dimethyl-2-(2-methylphenyl)ethyl]amino}-1-hydroxyethyl]-5-hydroxy-2H-1,4-benzoxazin-3(4H)-one, Beta-2 adrenergic receptor, Lysozyme, ... | | 著者 | Rasmussen, S.G.F, Choi, H.-J, Fung, J.J, Pardon, E, Casarosa, P, Chae, P.S, DeVree, B.T, Rosenbaum, D.M, Thian, F.S, Kobilka, T.S, Schnapp, A, Konetzki, I, Sunahara, R.K, Gellman, S.H, Pautsch, A, Steyaert, J, Weis, W.I, Kobilka, B.K. | | 登録日 | 2010-09-28 | | 公開日 | 2011-01-19 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Structure of a nanobody-stabilized active state of the b2 adrenoceptor
Nature, 469, 2011
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7SUB
 | | 3-oxoacyl-ACP reductase FabG | | 分子名称: | 3-oxoacyl-reductase, GLYCEROL | | 著者 | Thomas, L.M, Karr, E.A, Dinh, D.M. | | 登録日 | 2021-11-16 | | 公開日 | 2022-12-07 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Crystal structure of a putative 3-hydroxypimelyl-CoA dehydrogenase, Hcd1, from Syntrophus aciditrophicus strain SB at 1.78 A resolution
Acta Crystallogr.,Sect.F, 79, 2023
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7TH8
 | | Chickpea (Cicer arientinum) nodule-specific cysteine-rich peptide NCR13: Solution NMR structure of the isomer with C4:C10, C15:C30, and C23:C28 disulfide bonds | | 分子名称: | Nodule cysteine-rich protein 13 | | 著者 | Buchko, G.W, Zhou, M, Shah, D.M, Velivelli, S.L.S. | | 登録日 | 2022-01-10 | | 公開日 | 2022-02-02 | | 最終更新日 | 2024-10-30 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Chickpea (Cicer arientinum) nodule-specific cysteine-rich peptide NCR13: Solution NMR structure of the isomer with C4:C10, C15:C30, and C23:C28 disulfide bonds
To Be Published
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3QHR
 | | Structure of a pCDK2/CyclinA transition-state mimic | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CDK2 substrate peptide: PKTPKKAKKL, CHLORIDE ION, ... | | 著者 | Young, M.A, Jacobsen, D.M, Bao, Z.Q. | | 登録日 | 2011-01-26 | | 公開日 | 2011-05-25 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | | 主引用文献 | Briefly Bound to Activate: Transient Binding of a Second Catalytic Magnesium Activates the Structure and Dynamics of CDK2 Kinase for Catalysis.
Structure, 19, 2011
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3RGN
 | | Crystal structure of spin-labeled BtuB W371R1 | | 分子名称: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, MAGNESIUM ION, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate, ... | | 著者 | Freed, D.M, Horanyi, P.S, Wiener, M.C, Cafiso, D.S. | | 登録日 | 2011-04-08 | | 公開日 | 2011-10-26 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Molecular Origin of Electron Paramagnetic Resonance Line Shapes on β-Barrel Membrane Proteins: The Local Solvation Environment Modulates Spin-Label Configuration
Biochemistry, 50, 2011
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