7MYO
| Cryo-EM structure of p110alpha in complex with p85alpha inhibited by BYL-719 | 分子名称: | (2S)-N~1~-{4-methyl-5-[2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl]-1,3-thiazol-2-yl}pyrrolidine-1,2-dicarboxamide, Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | 著者 | Liu, X, Yang, S, Hart, J.R, Xu, Y, Zou, X, Zhang, H, Zhou, Q, Xia, T, Zhang, Y, Yang, D, Wang, M.-W, Vogt, P.K. | 登録日 | 2021-05-21 | 公開日 | 2021-11-10 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.92 Å) | 主引用文献 | Cryo-EM structures of PI3K alpha reveal conformational changes during inhibition and activation. Proc.Natl.Acad.Sci.USA, 118, 2021
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2MW5
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7MYN
| Cryo-EM Structure of p110alpha in complex with p85alpha | 分子名称: | Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | 著者 | Liu, X, Yang, S, Hart, J.R, Xu, Y, Zou, X, Zhang, H, Zhou, Q, Xia, T, Zhang, Y, Yang, D, Wang, M.-W, Vogt, P.K. | 登録日 | 2021-05-21 | 公開日 | 2021-11-10 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.79 Å) | 主引用文献 | Cryo-EM structures of PI3K alpha reveal conformational changes during inhibition and activation. Proc.Natl.Acad.Sci.USA, 118, 2021
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1B4A
| STRUCTURE OF THE ARGININE REPRESSOR FROM BACILLUS STEAROTHERMOPHILUS | 分子名称: | ARGININE REPRESSOR | 著者 | Ni, J, Sakanyan, V, Charlier, D, Glansdorff, N, Van Duyne, G.D. | 登録日 | 1998-12-18 | 公開日 | 1999-06-15 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure of the arginine repressor from Bacillus stearothermophilus. Nat.Struct.Biol., 6, 1999
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2N42
| EC-NMR Structure of Human H-RasT35S mutant protein Determined by Combining Evolutionary Couplings (EC) and Sparse NMR Data | 分子名称: | GTPase HRas | 著者 | Tang, Y, Huang, Y.J, Hopf, T.A, Sander, C, Marks, D, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2015-06-16 | 公開日 | 2015-07-01 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Protein structure determination by combining sparse NMR data with evolutionary couplings. Nat.Methods, 12, 2015
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2MWE
| NMR structure of FBP28 WW2 mutant Y438R, L453A DNDC | 分子名称: | Transcription elongation regulator 1 | 著者 | Macias, M.J, Scheraga, H, Sunol, D, Todorovski, T. | 登録日 | 2014-11-04 | 公開日 | 2014-12-03 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Folding kinetics of WW domains with the united residue force field for bridging microscopic motions and experimental measurements. Proc.Natl.Acad.Sci.USA, 111, 2014
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1B6Y
| 3,N4-ETHENO-2'-DEOXYCYTIDINE OPPOSITE ADENINE IN AN 11-MER DUPLEX, SOLUTION STRUCTURE FROM NMR AND MOLECULAR DYNAMICS, 2 STRUCTURES | 分子名称: | 5'-D(*CP*GP*TP*AP*CP*(EDC)P*CP*AP*TP*GP*C)-3', 5'-D(*GP*CP*AP*TP*GP*AP*GP*TP*AP*CP*G)-3' | 著者 | Korobka, A, Cullinan, D, Cosman, M, Grollman, A.P, Patel, D.J, Eisenberg, M, De Los Santos, C. | 登録日 | 1999-01-19 | 公開日 | 1999-01-27 | 最終更新日 | 2024-04-10 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of an oligodeoxynucleotide duplex containing the exocyclic lesion 3,N4-etheno-2'-deoxycytidine opposite 2'-deoxyadenosine, determined by NMR spectroscopy and restrained molecular dynamics. Biochemistry, 35, 1996
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2MOT
| Backbone Structure of Actin Depolymerizing Factor (ADF) of Toxoplasma gondii Based on Prot3DNMR Approach | 分子名称: | Actin depolymerizing factor ADF | 著者 | Kumar, D, Raikwal, N, Raval, I, Jaiswal, N, Shukla, V, Arora, A. | 登録日 | 2014-05-05 | 公開日 | 2015-05-27 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Prot3DNMR: A Simple and Swift Strategy for Backbone Structure Determination of Proteins by NMR To be Published
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2N7O
| NMR Structure of Peptide PG-990 in DPC micelles | 分子名称: | Peptide PG-990 | 著者 | Carotenuto, A, Merlino, F, Chai, M, Brancaccio, D, Yousif, A, Novellino, E, Hruby, V, Grieco, P. | 登録日 | 2015-09-16 | 公開日 | 2015-12-16 | 最終更新日 | 2017-10-11 | 実験手法 | SOLUTION NMR | 主引用文献 | Discovery of Novel Potent and Selective Agonists at the Melanocortin-3 Receptor. J.Med.Chem., 58, 2015
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7NAU
| Bacterial 30S ribosomal subunit assembly complex state C (Consensus Refinement) | 分子名称: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Kaminishi, T, Capuni, R, Astigarraga, E, Gil-Carton, D, Fucini, P, Connell, S. | 登録日 | 2021-01-25 | 公開日 | 2021-12-08 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.78 Å) | 主引用文献 | A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit. Sci Adv, 7, 2021
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7NAT
| Bacterial 30S ribosomal subunit assembly complex state A (Consensus refinement) | 分子名称: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Kaminishi, T, Capuni, R, Astigarraga, E, Gil-Carton, D, Fucini, P, Connell, S. | 登録日 | 2021-01-25 | 公開日 | 2021-12-08 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.59 Å) | 主引用文献 | A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit. Sci Adv, 7, 2021
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7NAV
| Bacterial 30S ribosomal subunit assembly complex state D (Consensus refinement) | 分子名称: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Kaminishi, T, Capuni, R, Astigarraga, E, Gil-Carton, D, Fucini, P, Connell, S. | 登録日 | 2021-01-25 | 公開日 | 2021-12-08 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | 主引用文献 | A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit. Sci Adv, 7, 2021
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7NA8
| Structures of human ghrelin receptor-Gi complexes with ghrelin and a synthetic agonist | 分子名称: | 1-(methanesulfonyl)-1'-(2-methyl-L-alanyl-O-benzyl-D-seryl)-1,2-dihydrospiro[indole-3,4'-piperidine], Antibody fragment, CHOLESTEROL, ... | 著者 | Liu, H, Sun, D, Sun, J, Zhang, C. | 登録日 | 2021-06-20 | 公開日 | 2021-12-15 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Structural basis of human ghrelin receptor signaling by ghrelin and the synthetic agonist ibutamoren Nat Commun, 12, 2021
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7NA7
| Structures of human ghrelin receptor-Gi complexes with ghrelin and a synthetic agonist | 分子名称: | Antibody fragment, CHOLESTEROL, Ghrelin-27, ... | 著者 | Liu, H, Sun, D, Sun, J, Zhang, C. | 登録日 | 2021-06-20 | 公開日 | 2021-12-15 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Structural basis of human ghrelin receptor signaling by ghrelin and the synthetic agonist ibutamoren Nat Commun, 12, 2021
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2MR6
| Solution NMR Structure of De novo designed protein, Northeast Structural Genomics Consortium (NESG) Target OR462 | 分子名称: | De novo designed Protein OR462 | 著者 | Xu, X, Nivon, L, Federizon, J.F, Maglaqui, M, Janjua, H, Mao, L, Xiao, R, Kornhaber, G, Baker, D, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2014-07-01 | 公開日 | 2014-08-06 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR Structure of De novo designed protein, Northeast Structural Genomics Consortium (NESG) Target OR462 To be Published
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7NAX
| Complete Bacterial 30S ribosomal subunit assembly complex state I (Consensus Refinement) | 分子名称: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Lopez-Alonso, J, Kaminishi, T, Capuni, R, Astigarraga, E, Gil-Carton, D, Fucini, P, Connell, S. | 登録日 | 2021-01-25 | 公開日 | 2021-12-08 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.96 Å) | 主引用文献 | A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit. Sci Adv, 7, 2021
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1BJT
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7NAR
| Complete Bacterial 30S ribosomal subunit assembly complex state F (+RsgA)(Consensus Refinement) | 分子名称: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Kaminishi, T, Capuni, R, Astigarraga, E, Gil-Carton, D, Fucini, P, Connell, S. | 登録日 | 2021-01-25 | 公開日 | 2021-12-08 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit. Sci Adv, 7, 2021
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7N41
| Crystal structure of TagA with UDP-ManNAc | 分子名称: | (2R,3S,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen diphosphate (non-preferred name), N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase | 著者 | Martinez, O.E, Cascio, D, Clubb, R.T. | 登録日 | 2021-06-03 | 公開日 | 2021-12-29 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Insight into the molecular basis of substrate recognition by the wall teichoic acid glycosyltransferase TagA. J.Biol.Chem., 298, 2021
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2ND2
| Solution structure of the de novo mini protein gHHH_06 | 分子名称: | De novo mini protein HHH_06 | 著者 | Pulavarti, S.V, Eletsky, A, Bahl, C.D, Buchko, G.W, Baker, D, Szyperski, T. | 登録日 | 2016-04-22 | 公開日 | 2016-09-21 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Accurate de novo design of hyperstable constrained peptides. Nature, 538, 2016
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1BK4
| CRYSTAL STRUCTURE OF RABBIT LIVER FRUCTOSE-1,6-BISPHOSPHATASE AT 2.3 ANGSTROM RESOLUTION | 分子名称: | MAGNESIUM ION, PROTEIN (FRUCTOSE-1,6-BISPHOSPHATASE), SULFATE ION | 著者 | Ghosh, D, Weeks, C.M, Erman, M, Roszak, A.W, Kaiser, R, Jornvall, H. | 登録日 | 1998-07-14 | 公開日 | 1998-07-22 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of rabbit liver fructose 1,6-bisphosphatase at 2.3 A resolution. Acta Crystallogr.,Sect.D, 55, 1999
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1BQU
| CYTOKYNE-BINDING REGION OF GP130 | 分子名称: | GLYCEROL, PROTEIN (GP130), SULFATE ION | 著者 | Bravo, J, Staunton, D, Heath, J.K, Jones, E.Y. | 登録日 | 1998-08-18 | 公開日 | 1998-08-26 | 最終更新日 | 2022-12-21 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of a cytokine-binding region of gp130. EMBO J., 17, 1998
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2N41
| Solution NMR Structure of DE NOVO DESIGNED PROTEIN Top7NNSTYCC, Northeast Structural Genomics Consortium (NESG) Target OR34 | 分子名称: | OR34 | 著者 | Liu, G, Chan, K, Basanta, B, Xiao, R, Janjua, H, Kogan, S, Maglaqui, M, Ciccosanti, C, Acton, T.B, Kornhaber, G, Everett, J.K, Baker, D, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2015-06-16 | 公開日 | 2016-03-02 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR Structure of DE NOVO DESIGNED PROTEIN Top7NNSTYCC, Northeast Structural Genomics Consortium (NESG) Target OR34 To be Published
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1BVQ
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1BY3
| FHUA FROM E. COLI | 分子名称: | N-OCTYL-2-HYDROXYETHYL SULFOXIDE, PROTEIN (FERRICHROME-IRON RECEPTOR PRECURSOR (FHUA)) | 著者 | Locher, K.P, Rees, B, Koebnik, R, Mitschler, A, Moulinier, L, Rosenbusch, J.P, Moras, D. | 登録日 | 1998-10-22 | 公開日 | 1999-01-13 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.74 Å) | 主引用文献 | Transmembrane signaling across the ligand-gated FhuA receptor: crystal structures of free and ferrichrome-bound states reveal allosteric changes. Cell(Cambridge,Mass.), 95, 1998
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