7N41

Crystal structure of TagA with UDP-ManNAc

Summary for 7N41

• Entry DOI: 10.2210/pdb7n41/pdb
• Descriptor: N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase, (2R,3S,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen diphosphate (non-preferred name) (2 entities in total)
• Functional Keywords: glycosyltransferase, wall teichoic acid enzyme, beta-n-2 acetylmannosaminyltransferase, transferase, udp-n-acetylmannosamine
• Biological source: Thermoanaerobacter italicus (strain DSM 9252 / Ab9)
• Total number of polymer chains: 3
• Total formula weight: 85542.46

Authors

Martinez, O.E.,Cascio, D.,Clubb, R.T. (deposition date: 2021-06-03, release date: 2021-12-29, Last modification date: 2023-10-18)

• Primary citation: Martinez, O.E.,Mahoney, B.J.,Goring, A.K.,Yi, S.W.,Tran, D.P.,Cascio, D.,Phillips, M.L.,Muthana, M.M.,Chen, X.,Jung, M.E.,Loo, J.A.,Clubb, R.T.; Insight into the molecular basis of substrate recognition by the wall teichoic acid glycosyltransferase TagA.; J.Biol.Chem., 298:101464-101464, 2021; PubMed: 34864059; DOI: 10.1016/j.jbc.2021.101464

Experimental method

X-RAY DIFFRACTION (3.3 Å)