2V9P
| Crystal structure of papillomavirus E1 hexameric helicase DNA-free form | Descriptor: | MAGNESIUM ION, PHOSPHATE ION, REPLICATION PROTEIN E1 | Authors: | Sanders, C.M, Kovalevskiy, O.V, Sizov, D, Lebedev, A.A, Isupov, M.N, Antson, A.A. | Deposit date: | 2007-08-24 | Release date: | 2007-10-02 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Papillomavirus E1 Helicase Assembly Maintains an Asymmetric State in the Absence of DNA and Nucleotide Cofactors. Nucleic Acids Res., 35, 2007
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7MP2
| CRYSTAL STRUCTURE OF NATIVE BOVINE ARRESTIN 1 IN COMPLEX WITH 1D-MYO-INOSITOL 1,5-BISDIPHOSPHATE TETRAKISPHOSPHATE (1,5-PP IP4) | Descriptor: | (1R,3S,4R,5S,6R)-2,4,5,6-tetrakis(phosphonooxy)cyclohexane-1,3-diyl bis[trihydrogen (diphosphate)], S-arrestin | Authors: | Sander, C.L, Palczewski, K, Kiser, P.D. | Deposit date: | 2021-05-04 | Release date: | 2021-10-13 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural evidence for visual arrestin priming via complexation of phosphoinositols. Structure, 30, 2022
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7MOR
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7MP1
| CRYSTAL STRUCTURE OF NATIVE BOVINE ARRESTIN 1 IN COMPLEX WITH 1,5-DI-METHYLENEBISPHOSPHONATE INOSITOL TETRAKISPHOSPHATE (1,5-PCP-IP4) | Descriptor: | S-arrestin, {[(1R,3S,4S,5R,6S)-2,4,5,6-tetrakis(phosphonooxy)cyclohexane-1,3-diyl]bis[oxy(hydroxyphosphoryl)methanediyl]}bis(phosphonic acid) | Authors: | Sander, C.L, Palczewski, K, Kiser, P.D. | Deposit date: | 2021-05-04 | Release date: | 2021-10-13 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.66 Å) | Cite: | Structural evidence for visual arrestin priming via complexation of phosphoinositols. Structure, 30, 2022
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7MP0
| CRYSTAL STRUCTURE OF NATIVE BOVINE ARRESTIN 1 IN COMPLEX WITH 1D-MYO-INOSITOL 5-DIPHOSPHATE PENTAKISPHOSPHATE (5-PP IP5) | Descriptor: | (1r,2R,3S,4s,5R,6S)-2,3,4,5,6-pentakis(phosphonooxy)cyclohexyl trihydrogen diphosphate, 2-ETHOXYETHANOL, S-arrestin | Authors: | Sander, C.L, Palczewski, K, Kiser, P.D. | Deposit date: | 2021-05-04 | Release date: | 2021-10-13 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural evidence for visual arrestin priming via complexation of phosphoinositols. Structure, 30, 2022
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2NDJ
| Structural Basis for KCNE3 and Estrogen Modulation of the KCNQ1 Channel | Descriptor: | Potassium voltage-gated channel subfamily E member 3 | Authors: | Sanders, C.R, Van Horn, W.D, Kroncke, B.M, Sisco, N.J, Meiler, J, Vanoye, C.G, Song, Y, Nannemann, D.P, Welch, R.C, Kang, C, Smith, J, George, A.L. | Deposit date: | 2016-06-09 | Release date: | 2016-09-21 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Structural basis for KCNE3 modulation of potassium recycling in epithelia. Sci Adv, 2, 2016
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2JEX
| Transcription activator structure reveals redox control of a replication initiation reaction | Descriptor: | REGULATORY PROTEIN E2 | Authors: | Sanders, C.M, Sizov, D, Seavers, P.R, Ortiz-Lombardia, M, Antson, A.A. | Deposit date: | 2007-01-24 | Release date: | 2007-05-15 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Transcription Activator Structure Reveals Redox Control of a Replication Initiation Reaction. Nucleic Acids Res., 35, 2007
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2JEU
| Transcription activator structure reveals redox control of a replication initiation reaction | Descriptor: | REGULATORY PROTEIN E2 | Authors: | Sanders, C.M, Sizov, D, Seavers, P.R, Ortiz-Lombardia, M, Antson, A.A. | Deposit date: | 2007-01-23 | Release date: | 2007-05-15 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Transcription Activator Structure Reveals Redox Control of a Replication Initiation Reaction. Nucleic Acids Res., 35, 2007
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7JTB
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7JSM
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7JXA
| CRYSTAL STRUCTURE OF NATIVE BOVINE ARRESTIN 1 IN COMPLEX WITH INOSITOL 1,4,5-TRIPHOSPHATE | Descriptor: | 2-ETHOXYETHANOL, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, S-arrestin, ... | Authors: | Sander, C.L, Palczewski, K, Kiser, P.D. | Deposit date: | 2020-08-26 | Release date: | 2021-10-13 | Last modified: | 2022-02-16 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural evidence for visual arrestin priming via complexation of phosphoinositols. Structure, 30, 2022
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8RQU
| Structure of TEM1 beta-lactamase variant 70.a | Descriptor: | Beta-lactamase TEM-1, MAGNESIUM ION | Authors: | Napie, E, Fram, B.F, Gauthier, N.P, Sander, C, Khan, A.R. | Deposit date: | 2024-01-19 | Release date: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Simultaneous enhancement of multiple functional properties using evolution-informed protein design. Biorxiv, 2023
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5A9K
| Structural basis for DNA strand separation by a hexameric replicative helicase | Descriptor: | MAGNESIUM ION, PHOSPHATE ION, REPLICATION PROTEIN E1 | Authors: | Chaban, Y, Stead, J.A, Ryzhenkova, K, Whelan, F, Lamber, K, Antson, F, Sanders, C.M, Orlova, E.V. | Deposit date: | 2015-07-21 | Release date: | 2015-08-26 | Last modified: | 2017-08-02 | Method: | ELECTRON MICROSCOPY (19 Å) | Cite: | Structural Basis for DNA Strand Separation by a Hexameric Replicative Helicase. Nucleic Acids Res., 43, 2015
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8GII
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8GIJ
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6MIE
| Solution NMR structure of the KCNQ1 voltage-sensing domain | Descriptor: | Potassium voltage-gated channel subfamily KQT member 1 | Authors: | Taylor, K.C, Kuenze, G, Smith, J.A, Meiler, J, McFeeters, R.L, Sanders, C.R. | Deposit date: | 2018-09-19 | Release date: | 2020-03-04 | Last modified: | 2020-03-11 | Method: | SOLUTION NMR | Cite: | Structure and physiological function of the human KCNQ1 channel voltage sensor intermediate state. Elife, 9, 2020
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6HPQ
| Crystal structure of human Pif1 helicase in complex with AMP-PNP, brominated crystal form. | Descriptor: | ATP-dependent DNA helicase PIF1, BROMIDE ION, MAGNESIUM ION, ... | Authors: | Ledikov, V.M, Dehghani-Tafti, S, Bax, B, Sanders, C.M, Antson, A.A. | Deposit date: | 2018-09-21 | Release date: | 2019-01-23 | Last modified: | 2019-04-17 | Method: | X-RAY DIFFRACTION (1.43 Å) | Cite: | Structural and functional analysis of the nucleotide and DNA binding activities of the human PIF1 helicase. Nucleic Acids Res., 47, 2019
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7APD
| Bovine Papillomavirus E1 DNA helicase-replication fork complex | Descriptor: | DNA (36-MER), DNA (40-MER), Replication protein E1 | Authors: | Javed, A, Major, B, Stead, J, Sanders, C.M, Orlova, E.V. | Deposit date: | 2020-10-16 | Release date: | 2021-11-17 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Unwinding of a DNA replication fork by a hexameric viral helicase. Nat Commun, 12, 2021
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6HPH
| Crystal structure of human Pif1 helicase in complex with AMP-PNP | Descriptor: | ATP-dependent DNA helicase PIF1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | Authors: | Levdikov, V.M, Dehghani-Tafti, S, Bax, B.D, Sanders, C.M, Antson, A.A. | Deposit date: | 2018-09-20 | Release date: | 2019-01-23 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.13 Å) | Cite: | Structural and functional analysis of the nucleotide and DNA binding activities of the human PIF1 helicase. Nucleic Acids Res., 47, 2019
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2K21
| NMR structure of human KCNE1 in LMPG micelles at pH 6.0 and 40 degree C | Descriptor: | Potassium voltage-gated channel subfamily E member | Authors: | Kang, C, Tian, C, Sonnichsen, F.D, Smith, J.A, Meiler, J, George, A.L, Vanoye, C.G, Sanders, C.R, Kim, H. | Deposit date: | 2008-03-19 | Release date: | 2008-12-09 | Last modified: | 2021-10-20 | Method: | SOLUTION NMR | Cite: | Structure of KCNE1 and implications for how it modulates the KCNQ1 potassium channel. Biochemistry, 47, 2008
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1YO7
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6HPU
| Crystal structure of human Pif1 helicase in complex with ADP-AlF4 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent DNA helicase PIF1, MAGNESIUM ION, ... | Authors: | Levdikov, V.M, Dehghani-Tafti, S, Bax, B.D, Sanders, C.M, Antson, A.A. | Deposit date: | 2018-09-21 | Release date: | 2019-01-23 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.96 Å) | Cite: | Structural and functional analysis of the nucleotide and DNA binding activities of the human PIF1 helicase. Nucleic Acids Res., 47, 2019
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6HPT
| Crystal structure of human Pif1 helicase, apoform. | Descriptor: | ATP-dependent DNA helicase PIF1, SULFATE ION | Authors: | Levdikov, V.M, Dehghani-Tafti, S, Bax, B.D, Sanders, C.M, Antson, A.A. | Deposit date: | 2018-09-21 | Release date: | 2019-01-23 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.44 Å) | Cite: | Structural and functional analysis of the nucleotide and DNA binding activities of the human PIF1 helicase. Nucleic Acids Res., 47, 2019
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2KDC
| NMR Solution Structure of E. coli diacylglycerol kinase (DAGK) in DPC micelles | Descriptor: | Diacylglycerol kinase | Authors: | Van Horn, W.D, Kim, H, Ellis, C.D, Hadziselimovic, A, Sulistijo, E.S, Karra, M.D, Tian, C, Sonnichsen, F.D, Sanders, C.R. | Deposit date: | 2009-01-06 | Release date: | 2009-07-07 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | Solution nuclear magnetic resonance structure of membrane-integral diacylglycerol kinase Science, 324, 2009
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1DTO
| CRYSTAL STRUCTURE OF THE COMPLETE TRANSACTIVATION DOMAIN OF E2 PROTEIN FROM THE HUMAN PAPILLOMAVIRUS TYPE 16 | Descriptor: | REGULATORY PROTEIN E2 | Authors: | Antson, A.A, Burns, J.E, Moroz, O.V, Scott, D.J, Sanders, C.M, Bronstein, I.B, Dodson, G.G, Wilson, K.S, Maitland, N. | Deposit date: | 2000-01-13 | Release date: | 2000-02-23 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of the intact transactivation domain of the human papillomavirus E2 protein. Nature, 403, 2000
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