NMR structure of human KCNE1 in LMPG micelles at pH 6.0 and 40 degree C

Summary for 2K21

DescriptorPotassium voltage-gated channel subfamily E member (1 entity in total)
Functional Keywordskcne1, membrane protein, potassium channel, mink, auxilliary subunit, micelles, ion transport, ionic channel, potassium transport, transmembrane, transport, voltage-gated channel
Biological sourceHomo sapiens (human)
Cellular locationMembrane; Single-pass type I membrane protein (By similarity) Q6FHJ6
Total number of polymer chains1
Total molecular weight15706.87
Kang, C.,Tian, C.,Sonnichsen, F.D.,Smith, J.A.,Meiler, J.,George, A.L.,Vanoye, C.G.,Sanders, C.R.,Kim, H. (deposition date: 2008-03-19, release date: 2008-12-09, Last modification date: 2011-07-13)
Primary citation
Kang, C.,Tian, C.,Sonnichsen, F.D.,Smith, J.A.,Meiler, J.,George, A.L.,Vanoye, C.G.,Kim, H.J.,Sanders, C.R.
Structure of KCNE1 and implications for how it modulates the KCNQ1 potassium channel.
Biochemistry, 47:7999-8006, 2008
PubMed: 18611041 (PDB entries with the same primary citation)
DOI: 10.1021/bi800875q
MImport into Mendeley
Experimental method
NMR Information

Structure validation

ClashscoreRamachandran outliersSidechain outliers22.3%21.6%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures