6HPU

Crystal structure of human Pif1 helicase in complex with ADP-AlF4

Summary for 6HPU

• Entry DOI: 10.2210/pdb6hpu/pdb
• Related: 6HPH 6HPQ 6HPT
• Descriptor: ATP-dependent DNA helicase PIF1, ADENOSINE-5'-DIPHOSPHATE, TETRAFLUOROALUMINATE ION, ... (4 entities in total)
• Functional Keywords: pif1, 5'-3' dna helicase, duplex unwinding, telomere maintenance, dna repair, hydrolase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 92076.13

Authors

Levdikov, V.M.,Dehghani-Tafti, S.,Bax, B.D.,Sanders, C.M.,Antson, A.A. (deposition date: 2018-09-21, release date: 2019-01-23, Last modification date: 2024-01-24)

• Primary citation: Dehghani-Tafti, S.,Levdikov, V.,Antson, A.A.,Bax, B.,Sanders, C.M.; Structural and functional analysis of the nucleotide and DNA binding activities of the human PIF1 helicase.; Nucleic Acids Res., 47:3208-3222, 2019; PubMed: 30698796; DOI: 10.1093/nar/gkz028

Experimental method

X-RAY DIFFRACTION (3.96 Å)