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6HPU

Crystal structure of human Pif1 helicase in complex with ADP-AlF4

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
ATP-dependent DNA helicase PIF1polymer41845483.62UniProt (Q9H611)
Pfam (PF05970)
Pfam (PF21530)
Homo sapiens (Human)DNA repair and recombination helicase PIF1,PIF1/RRM3 DNA helicase-like protein
2C, F
(A, B)
ADENOSINE-5'-DIPHOSPHATEnon-polymer427.22Chemie (ADP)
3D, G
(A, B)
TETRAFLUOROALUMINATE IONnon-polymer103.02Chemie (ALF)
4E, H
(A, B)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
Sequence modifications
A, B: 206 - 620 (UniProt: Q9H611)
PDBExternal DatabaseDetails
Ser 203-expression tag
Arg 204-expression tag
Met 205-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight90967.2
Non-Polymers*Number of molecules6
Total formula weight1109.0
All*Total formula weight92076.1
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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