6HPQ
Crystal structure of human Pif1 helicase in complex with AMP-PNP, brominated crystal form.
Summary for 6HPQ
Entry DOI | 10.2210/pdb6hpq/pdb |
Related | 6HPH 6HPT 6HPV |
Descriptor | ATP-dependent DNA helicase PIF1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | pif1, 5'-3' dna helicase, duplex unwinding, telomere maintenance, dna repair, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 92747.30 |
Authors | Ledikov, V.M.,Dehghani-Tafti, S.,Bax, B.,Sanders, C.M.,Antson, A.A. (deposition date: 2018-09-21, release date: 2019-01-23, Last modification date: 2019-04-17) |
Primary citation | Dehghani-Tafti, S.,Levdikov, V.,Antson, A.A.,Bax, B.,Sanders, C.M. Structural and functional analysis of the nucleotide and DNA binding activities of the human PIF1 helicase. Nucleic Acids Res., 47:3208-3222, 2019 Cited by PubMed: 30698796DOI: 10.1093/nar/gkz028 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.43 Å) |
Structure validation
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