6HPH

Crystal structure of human Pif1 helicase in complex with AMP-PNP

Summary for 6HPH

Entry DOI	10.2210/pdb6hph/pdb
Related	6HPQ 6HPT 6HPV
Descriptor	ATP-dependent DNA helicase PIF1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, MAGNESIUM ION, ... (4 entities in total)
Functional Keywords	pif1, 5'-3' dna helicase, duplex unwinding, telomere maintenance, dna repair, hydrolase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	46014.08
Authors	Levdikov, V.M.,Dehghani-Tafti, S.,Bax, B.D.,Sanders, C.M.,Antson, A.A. (deposition date: 2018-09-20, release date: 2019-01-23, Last modification date: 2024-01-24)
Primary citation	Dehghani-Tafti, S.,Levdikov, V.,Antson, A.A.,Bax, B.,Sanders, C.M. Structural and functional analysis of the nucleotide and DNA binding activities of the human PIF1 helicase. Nucleic Acids Res., 47:3208-3222, 2019 Cited by PubMed: 30698796 DOI: 10.1093/nar/gkz028 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.13 Å)

Structure validation