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6HPH

Crystal structure of human Pif1 helicase in complex with AMP-PNP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
ATP-dependent DNA helicase PIF1polymer41845483.61UniProt (Q9H611)
Pfam (PF05970)
Pfam (PF21530)
Homo sapiens (Human)DNA repair and recombination helicase PIF1,PIF1/RRM3 DNA helicase-like protein
2B
(A)
PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTERnon-polymer506.21Chemie (ANP)
3C
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
4D
(A)
waterwater18.0857Chemie (HOH)
Sequence modifications
A: 206 - 620 (UniProt: Q9H611)
PDBExternal DatabaseDetails
Ser 203-expression tag
Arg 204-expression tag
Met 205-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight45483.6
Non-Polymers*Number of molecules2
Total formula weight530.5
All*Total formula weight46014.1
*Water molecules are not included.

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PDB entries from 2025-06-18

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