5E0B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5e0b by Molmil](/molmil-images/mine/5e0b) | Crystal structure of the complex of Peptidoglycan recognition protein PGRP-S with N-Acetyl Muramic acid at 2.6 A resolution | 分子名称: | GLYCEROL, L(+)-TARTARIC ACID, N-acetyl-beta-muramic acid, ... | 著者 | Sharma, P, Yamini, S, Dube, D, Sinha, M, Kaur, P, Sharma, S, Singh, T.P. | 登録日 | 2015-09-28 | 公開日 | 2015-10-14 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal structure of the complex of Peptidoglycan recognition protein PGRP-S with N-Acetyl Muramic acid at 2.6 A resolution To Be Published
|
|
1NOG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1nog by Molmil](/molmil-images/mine/1nog) | Crystal Structure of Conserved Protein 0546 from Thermoplasma Acidophilum | 分子名称: | conserved hypothetical protein TA0546 | 著者 | Saridakis, V, Sanishvili, R, Iakounine, A, Xu, X, Pennycooke, M, Gu, J, Joachimiak, A, Arrowsmith, C.H, Edwards, A.M, Christendat, D, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2003-01-16 | 公開日 | 2003-07-29 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | The structural basis for methylmalonic aciduria. The crystal structure of archaeal ATP:cobalamin adenosyltransferase. J.Biol.Chem., 279, 2004
|
|
5E3O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5e3o by Molmil](/molmil-images/mine/5e3o) | |
5E5X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5e5x by Molmil](/molmil-images/mine/5e5x) | |
6N17
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6n17 by Molmil](/molmil-images/mine/6n17) | Crystal structure of Tdp1 catalytic domain in complex with compound XZ577 | 分子名称: | 1,2-ETHANEDIOL, 4-[(3-carboxypropanoyl)amino]benzene-1,2-dicarboxylic acid, DIMETHYL SULFOXIDE, ... | 著者 | Lountos, G.T, Zhao, X.Z, Kiselev, E, Tropea, J.E, Needle, D, Burke Jr, T.R, Pommier, Y, Waugh, D.S. | 登録日 | 2018-11-08 | 公開日 | 2019-07-03 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.639 Å) | 主引用文献 | Identification of a ligand binding hot spot and structural motifs replicating aspects of tyrosyl-DNA phosphodiesterase I (TDP1) phosphoryl recognition by crystallographic fragment cocktail screening. Nucleic Acids Res., 47, 2019
|
|
6NRC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6nrc by Molmil](/molmil-images/mine/6nrc) | hTRiC-hPFD Class3 | 分子名称: | Prefoldin subunit 1, Prefoldin subunit 2, Prefoldin subunit 3, ... | 著者 | Gestaut, D, Roh, S.H, Ma, B, Pintilie, G, Joachimiak, L.A, Leitner, A, Walzthoeni, T, Aebersold, R, Chiu, W, Frydman, J. | 登録日 | 2019-01-23 | 公開日 | 2019-06-19 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (8.3 Å) | 主引用文献 | The Chaperonin TRiC/CCT Associates with Prefoldin through a Conserved Electrostatic Interface Essential for Cellular Proteostasis. Cell, 177, 2019
|
|
5E7D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5e7d by Molmil](/molmil-images/mine/5e7d) | Crystal Structure of the fifth bromodomain of human PB1 in complex with a hydroxyphenyl ligand | 分子名称: | (2E)-3-(dimethylamino)-1-(2-hydroxyphenyl)prop-2-en-1-one, 1,2-ETHANEDIOL, Protein polybromo-1 | 著者 | Filippakopoulos, P, Picaud, S, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Owen, D, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2015-10-12 | 公開日 | 2016-10-12 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | Crystal Structure of the fifth bromodomain of human PB1 in complex with a hydroxyphenyl ligand To Be Published
|
|
5E2X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5e2x by Molmil](/molmil-images/mine/5e2x) | The crystal structure of the C-terminal domain of Ebola (Tai Forest) nucleoprotein | 分子名称: | NONAETHYLENE GLYCOL, NP | 著者 | Baker, L.E, Handing, K.B, Derewenda, U, Utepbergenov, D, Derewenda, Z.S. | 登録日 | 2015-10-01 | 公開日 | 2015-10-21 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Molecular architecture of the nucleoprotein C-terminal domain from the Ebola and Marburg viruses. Acta Crystallogr D Struct Biol, 72, 2016
|
|
2XTP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2xtp by Molmil](/molmil-images/mine/2xtp) | |
5BWN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5bwn by Molmil](/molmil-images/mine/5bwn) | |
6NM2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6nm2 by Molmil](/molmil-images/mine/6nm2) | NMR Structure of WW291 | 分子名称: | WW291 peptide | 著者 | Wang, G, Zarena, D. | 登録日 | 2019-01-10 | 公開日 | 2020-07-15 | 最終更新日 | 2020-09-09 | 実験手法 | SOLUTION NMR | 主引用文献 | The pi Configuration of the WWW Motif of a Short Trp-Rich Peptide Is Critical for Targeting Bacterial Membranes, Disrupting Preformed Biofilms, and Killing Methicillin-Resistant Staphylococcus aureus. Biochemistry, 56, 2017
|
|
5BYZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5byz by Molmil](/molmil-images/mine/5byz) | ERK5 in complex with small molecule | 分子名称: | 4-({5-fluoro-4-[2-methyl-1-(propan-2-yl)-1H-imidazol-5-yl]pyrimidin-2-yl}amino)-N-[2-(piperidin-1-yl)ethyl]benzamide, GLYCEROL, Mitogen-activated protein kinase 7 | 著者 | Chen, H, Tucker, J, Wang, X, Gavine, P.R, Philips, C, Augustin, M.A, Schreiner, P, Steinbacher, S, Preston, M, Ogg, D. | 登録日 | 2015-06-11 | 公開日 | 2016-05-04 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Discovery of a novel allosteric inhibitor-binding site in ERK5: comparison with the canonical kinase hinge ATP-binding site. Acta Crystallogr D Struct Biol, 72, 2016
|
|
5C2T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5c2t by Molmil](/molmil-images/mine/5c2t) | Crystal structure of Mitochondrial rhodoquinol-fumarate reductase from Ascaris suum with rhodoquinone-2 | 分子名称: | 2-amino-5-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-3-methoxy-6-methylcyclohexa-2,5-diene-1,4-dione, Cytochrome b-large subunit, FE2/S2 (INORGANIC) CLUSTER, ... | 著者 | Harada, S, Shiba, T, Sato, D, Yamamoto, A, Nagahama, M, Yone, A, Inaoka, D.K, Sakamoto, K, Inoue, M, Honma, T, Kita, K. | 登録日 | 2015-06-16 | 公開日 | 2015-08-05 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Structural Insights into the Molecular Design of Flutolanil Derivatives Targeted for Fumarate Respiration of Parasite Mitochondria Int J Mol Sci, 16, 2015
|
|
6NQT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6nqt by Molmil](/molmil-images/mine/6nqt) | GalNac-T2 soaked with UDP-sugar | 分子名称: | MANGANESE (II) ION, Polypeptide N-acetylgalactosaminyltransferase 2, [[(2~{R},3~{S},4~{R},5~{R})-5-[2,4-bis(oxidanylidene)pyrimidin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{R},4~{R},5~{R},6~{R})-3-(hex-5-ynoylamino)-6-(hydroxymethyl)-4,5-bis(oxidanyl)oxan-2-yl] hydrogen phosphate | 著者 | Fernandez, D, Bertozzi, C.R, Schumann, B, Agbay, A. | 登録日 | 2019-01-21 | 公開日 | 2020-01-29 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | Bump-and-Hole Engineering Identifies Specific Substrates of Glycosyltransferases in Living Cells. Mol.Cell, 78, 2020
|
|
5C65
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5c65 by Molmil](/molmil-images/mine/5c65) | Structure of the human glucose transporter GLUT3 / SLC2A3 | 分子名称: | CHOLESTEROL HEMISUCCINATE, Octyl Glucose Neopentyl Glycol, Solute carrier family 2, ... | 著者 | Pike, A.C.W, Quigley, A, Chu, A, Tessitore, A, Xia, X, Mukhopadhyay, S, Wang, D, Kupinska, K, Strain-Damerell, C, Chalk, R, Burgess-Brown, N.A, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC) | 登録日 | 2015-06-22 | 公開日 | 2015-07-08 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Structure of the human glucose transporter GLUT3 / SLC2A3 To Be Published
|
|
5C7D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5c7d by Molmil](/molmil-images/mine/5c7d) | Fragment-Based Drug Discovery Targeting Inhibitor of Apoptosis Proteins: Compound 17 | 分子名称: | (2R)-4-[2-(6-chloro-2,3-dihydro-1H-pyrrolo[3,2-c]pyridin-1-yl)-2-oxoethyl]-2-methylpiperazin-1-ium, E3 ubiquitin-protein ligase XIAP, ZINC ION | 著者 | Chessari, G, Buck, I.M, Day, J.E.H, Day, P.J, Iqbal, A, Johnson, C.N, Lewis, E.J, Martins, V, Miller, D, Reader, M, Rees, D.C, Rich, S.J, Tamanini, E, Vitorino, M, Ward, G.A, Williams, P.A, Williams, G, Wilsher, N.E, Woolford, A.J.-A. | 登録日 | 2015-06-24 | 公開日 | 2015-08-12 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Fragment-Based Drug Discovery Targeting Inhibitor of Apoptosis Proteins: Discovery of a Non-Alanine Lead Series with Dual Activity Against cIAP1 and XIAP. J.Med.Chem., 58, 2015
|
|
6NU5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6nu5 by Molmil](/molmil-images/mine/6nu5) | Pyruvate Kinase M2 Mutant - S437Y in Complex with L-cysteine | 分子名称: | 1,2-ETHANEDIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CYSTEINE, ... | 著者 | Srivastava, D, Nandi, S, Dey, M. | 登録日 | 2019-01-30 | 公開日 | 2019-08-21 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Mechanistic and Structural Insights into Cysteine-Mediated Inhibition of Pyruvate Kinase Muscle Isoform 2. Biochemistry, 58, 2019
|
|
5CCR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ccr by Molmil](/molmil-images/mine/5ccr) | Human Cyclophilin D Complexed with Inhibitor | 分子名称: | DI(HYDROXYETHYL)ETHER, FORMIC ACID, POTASSIUM ION, ... | 著者 | Gibson, R.P, Shore, E, Kershaw, N, Awais, M, Javed, A, Latawiec, D, Pandalaneni, S, Wen, L, Berry, N, O'Neill, P, Sutton, R, Lian, L.Y. | 登録日 | 2015-07-02 | 公開日 | 2016-07-20 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Human Cyclophilin D Complexed with Inhibitor To Be Published
|
|
6O2L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6o2l by Molmil](/molmil-images/mine/6o2l) | |
5CDW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5cdw by Molmil](/molmil-images/mine/5cdw) | Crystal Structure Analysis of a mutant Grb2 SH2 domain (W121G) with a pYVNV peptide | 分子名称: | Growth factor receptor-bound protein 2, SER-PTR-VAL-ASN-VAL-GLN | 著者 | Papaioannou, D, Geibel, S, Kunze, M, Kay, C, Waksman, G. | 登録日 | 2015-07-05 | 公開日 | 2016-05-25 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.602 Å) | 主引用文献 | Structural and biophysical investigation of the interaction of a mutant Grb2 SH2 domain (W121G) with its cognate phosphopeptide. Protein Sci., 25, 2016
|
|
5CMN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5cmn by Molmil](/molmil-images/mine/5cmn) | FLRT3 LRR domain in complex with LPHN3 Olfactomedin domain | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Latrophilin-3, ... | 著者 | Lu, Y, Salzman, G, Arac, D. | 登録日 | 2015-07-17 | 公開日 | 2015-08-12 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.605 Å) | 主引用文献 | Structural Basis of Latrophilin-FLRT-UNC5 Interaction in Cell Adhesion. Structure, 23, 2015
|
|
4NDY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ndy by Molmil](/molmil-images/mine/4ndy) | Human MHF1-MHF2 DNA complex | 分子名称: | Centromere protein S, Centromere protein X, DNA (26-MER) | 著者 | Zhao, Q, Saro, D, Sachpatzidis, A, Sung, P, Xiong, Y. | 登録日 | 2013-10-28 | 公開日 | 2014-01-22 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (6.999 Å) | 主引用文献 | The MHF complex senses branched DNA by binding a pair of crossover DNA duplexes. Nat Commun, 5, 2014
|
|
5COP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5cop by Molmil](/molmil-images/mine/5cop) | X-ray crystal structure of wild type HIV-1 protease in complex with GRL-097 | 分子名称: | (3R,3aS,4S,7aS)-3-hydroxyhexahydro-4H-furo[2,3-b]pyran-4-yl [(2S,3R)-4-{[(4-aminophenyl)sulfonyl](2-methylpropyl)amino}-3-hydroxy-1-(4-methoxyphenyl)butan-2-yl]carbamate, HIV-1 protease | 著者 | Yedidi, R.S, Hayashi, H, Aoki, M, Das, D, Ghosh, A.K, Mitsuya, H. | 登録日 | 2015-07-20 | 公開日 | 2016-01-13 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | C-5-Modified Tetrahydropyrano-Tetrahydofuran-Derived Protease Inhibitors (PIs) Exert Potent Inhibition of the Replication of HIV-1 Variants Highly Resistant to Various PIs, including Darunavir. J.Virol., 90, 2015
|
|
1QP5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1qp5 by Molmil](/molmil-images/mine/1qp5) | |
2XSL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2xsl by Molmil](/molmil-images/mine/2xsl) | The crystal structure of a Thermus thermophilus tRNAGly acceptor stem microhelix at 1.6 Angstroem resolution | 分子名称: | 5'-R(*CP*UP*CP*CP*CP*GP*C)-3', 5'-R(*GP*CP*GP*GP*GP*AP*G)-3' | 著者 | Oberthuer, D, Eichert, A, Erdmann, V.A, Fuerste, J.P, Betzel, C, Foerster, C. | 登録日 | 2010-10-29 | 公開日 | 2011-08-10 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | 主引用文献 | The Crystal Structure of a Thermus Thermophilus tRNA(Gly) Acceptor Stem Microhelix at 1.6 A Resolution. Biochem.Biophys.Res.Commun., 404, 2011
|
|